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Of course, proteins can attach to both electrodes. So, two configurations are possible
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Of course, proteins can attach to both electrodes. So, two configurations are possible.
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We fabricated 20 devices and observed the NDR in 30% of them.
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We fabricated 20 devices and observed the NDR in 30% of them.
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In the pathway model suggested by Beratan and Onuchic, specific electron tunneling pathways exist in which chemical bonds are predominant, hydrogen bonds are subsidiary, and throughspace routes are rare
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In the pathway model suggested by Beratan and Onuchic, specific electron tunneling pathways exist in which chemical bonds are predominant, hydrogen bonds are subsidiary, and throughspace routes are rare.
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∥ and it is known that the reduction of a disulfide is dissociative and leads to the cleavage of the S-S bond. As a consequence, our analogy with the Farver et al. case is still valid and we can continue to refer to their electron-tunneling pathway (we believe that a localized redox state located in the region of RSSR exists under the described experimental conditions).
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∥ and it is known that the reduction of a disulfide is dissociative and leads to the cleavage of the S-S bond. As a consequence, our analogy with the Farver et al. case is still valid and we can continue to refer to their electron-tunneling pathway (we believe that a localized redox state located in the region of RSSR exists under the described experimental conditions).
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For the sake of completeness, despite the many similarities we should mention also the differences in the experimental conditions between our work and that of the group at Oxford University concerning the applied forces that can result in difficulties in interconnecting a single protein at low forces, while higher forces can destroy this fragile molecule. This would explain also why NDR is visible only in a narrow window in the Oxford experiments
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For the sake of completeness, despite the many similarities we should mention also the differences in the experimental conditions between our work and that of the group at Oxford University concerning the applied forces that can result in difficulties in interconnecting a single protein at low forces, while higher forces can destroy this fragile molecule. This would explain also why NDR is visible only in a narrow window in the Oxford experiments.
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