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Volumn 17, Issue 7, 2005, Pages 816-822

Towards protein field-effect transistors: Report and model of a prototype

Author keywords

[No Author keywords available]

Indexed keywords

ADSORPTION; CHARGE TRANSFER; CHEMICAL BONDS; CHEMISORPTION; CONFORMATIONS; CURRENT VOLTAGE CHARACTERISTICS; ELECTRON BEAM LITHOGRAPHY; FLUORESCENCE; METALLORGANIC POLYMERS; MONOLAYERS; PROTEINS; REDOX REACTIONS; SELF ASSEMBLY; SEMICONDUCTOR JUNCTIONS; SPECTROSCOPIC ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 20244371491     PISSN: 09359648     EISSN: None     Source Type: Journal    
DOI: 10.1002/adma.200400628     Document Type: Article
Times cited : (85)

References (38)
  • 11
    • 17244372594 scopus 로고    scopus 로고
    • note
    • Self-assembly is a very interesting tool for the implementation of molecular devices and can be defined as the recognition and the sub-sequent self-organization of different elements, without any external source of information about the structure to be formed, as the total free energy of the system is minimized to result in a more stable state.
  • 16
    • 17244361968 scopus 로고    scopus 로고
    • note
    • The unfolding process results in a large solvent exposure of hydro-phobic residues that were shielded in the core of the protein in its native state.
  • 17
    • 17244365437 scopus 로고    scopus 로고
    • note
    • We call our protein device a field-effect transistor since we exploit a field effect to modulate the resistance of the protein monolayer and change the I-V characteristics of the device.
  • 18
    • 17244379287 scopus 로고    scopus 로고
    • note
    • -1 in about 40% of the space. Thus, it seems reasonable that the fold pattern of the biased proteins is also unperturbed by the electric field in the device, which is lower.
  • 19
    • 17244361845 scopus 로고    scopus 로고
    • note
    • More than 10 devices fabricated in different times and measured in different conditions exhibited ET. The shape of the characteristics remained the same when the integrations and the delay times were changed.
  • 28
    • 17244379286 scopus 로고    scopus 로고
    • note
    • For example, with 50 chains the maximum current is 35 pA. We remark that the number of active chains actually present in the experimental device is difficult to determine, but 50 chains (corresponding to approx. 2500 proteins, which is already computationally very demanding) is actually a conservative estimate.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.