-
1
-
-
0032982174
-
Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes
-
Albrecht JH, Hansen LK. Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes. Cell Growth Differ 10: 397-404, 1999.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 397-404
-
-
Albrecht, J.H.1
Hansen, L.K.2
-
2
-
-
0035555650
-
Activation and activities of the p53 tumour suppressor protein
-
Balint EE, Vousden KH. Activation and activities of the p53 tumour suppressor protein. Br J Cancer 85: 1813-1823, 2001.
-
(2001)
Br J Cancer
, vol.85
, pp. 1813-1823
-
-
Balint, E.E.1
Vousden, K.H.2
-
3
-
-
0028816461
-
Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: A mechanism of UDCA cytoprotection
-
Botla R, Spivey JR, Aguilar H, Bronk SF, Gores GJ. Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection. J Pharmacol Exp Ther 272: 930-938, 1995.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 930-938
-
-
Botla, R.1
Spivey, J.R.2
Aguilar, H.3
Bronk, S.F.4
Gores, G.J.5
-
4
-
-
18844397275
-
A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid
-
Castro RE, Solá S, Ma X, Ramalho RM, Kren BT, Steer CJ, Rodrigues CMP. A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid. J Hepatol 42: 897-906, 2005.
-
(2005)
J Hepatol
, vol.42
, pp. 897-906
-
-
Castro, R.E.1
Solá, S.2
Ma, X.3
Ramalho, R.M.4
Kren, B.T.5
Steer, C.J.6
Rodrigues, C.M.P.7
-
5
-
-
6344279913
-
The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons
-
Castro RE, Solá S, Ramalho RM, Steer CJ, Rodrigues CMP. The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons. J Pharmacol Exp Ther 311: 845-852, 2004.
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 845-852
-
-
Castro, R.E.1
Solá, S.2
Ramalho, R.M.3
Steer, C.J.4
Rodrigues, C.M.P.5
-
6
-
-
0029033333
-
p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis
-
Chen X, Bargonetti J, Prives C. p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis. Cancer Res 55: 4257-4263, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 4257-4263
-
-
Chen, X.1
Bargonetti, J.2
Prives, C.3
-
7
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014, 2004.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
8
-
-
0033774569
-
Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells
-
Conus S, Rosse T, Borner C. Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells. Cell Death Differ 7: 947-954, 2000.
-
(2000)
Cell Death Differ
, vol.7
, pp. 947-954
-
-
Conus, S.1
Rosse, T.2
Borner, C.3
-
9
-
-
0035138069
-
Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line
-
Duquesne F, Florent M, Roue G, Troussard X, Sola B. Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line. Cell Death Differ 8: 51-62, 2001.
-
(2001)
Cell Death Differ
, vol.8
, pp. 51-62
-
-
Duquesne, F.1
Florent, M.2
Roue, G.3
Troussard, X.4
Sola, B.5
-
10
-
-
0028072163
-
Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid
-
Earnest DL, Holubec H, Wali RK, Jolley CS, Bissonette M, Bhattacharyya AK, Roy H, Khare S, Brasitus TA. Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid. Cancer Res 54: 5071-5074, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 5071-5074
-
-
Earnest, D.L.1
Holubec, H.2
Wali, R.K.3
Jolley, C.S.4
Bissonette, M.5
Bhattacharyya, A.K.6
Roy, H.7
Khare, S.8
Brasitus, T.A.9
-
11
-
-
0035870123
-
Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis
-
Gao CF, Ren S, Zhang L, Nakajima T, Ichinose S, Hara T, Koike K, Tsuchida N. Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis. Exp Cell Res 265: 145-151, 2001.
-
(2001)
Exp Cell Res
, vol.265
, pp. 145-151
-
-
Gao, C.F.1
Ren, S.2
Zhang, L.3
Nakajima, T.4
Ichinose, S.5
Hara, T.6
Koike, K.7
Tsuchida, N.8
-
12
-
-
10244227982
-
Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis
-
Han EK, Begemann M, Sgambato A, Soh JW, Doki Y, Xing WQ, Liu W, Weinstein IB. Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis. Cell Growth Differ 7: 699-710, 1996.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 699-710
-
-
Han, E.K.1
Begemann, M.2
Sgambato, A.3
Soh, J.W.4
Doki, Y.5
Xing, W.Q.6
Liu, W.7
Weinstein, I.B.8
-
13
-
-
0032806092
-
Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis
-
Han EK, Ng SC, Arber N, Begemann M, Weinstein IB. Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis. Apoptosis 4: 213-219, 1999.
-
(1999)
Apoptosis
, vol.4
, pp. 213-219
-
-
Han, E.K.1
Ng, S.C.2
Arber, N.3
Begemann, M.4
Weinstein, I.B.5
-
14
-
-
0037404039
-
Bile acid regulation of hepatic physiology. IV. Bile acids and death receptors
-
Higuchi H, Gores GJ. Bile acid regulation of hepatic physiology. IV. Bile acids and death receptors. Am J Physiol Gastrointest Liver Physiol 284: G734-G738, 2003.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Higuchi, H.1
Gores, G.J.2
-
15
-
-
0027938209
-
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
-
Hunter T, Pines J. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 79: 573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
16
-
-
0030913556
-
Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide
-
Kren BT, Cole-Strauss A, Kmiec EB, Steer CJ. Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide. Hepatology 25: 1462-1468, 1997.
-
(1997)
Hepatology
, vol.25
, pp. 1462-1468
-
-
Kren, B.T.1
Cole-Strauss, A.2
Kmiec, E.B.3
Steer, C.J.4
-
18
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 275: 16202-16212, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
19
-
-
0022970827
-
Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction
-
Mariash CN, Seelig S, Schwartz HL, Oppenheimer JH. Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction. J Biol Chem 261: 9583-9586, 1986.
-
(1986)
J Biol Chem
, vol.261
, pp. 9583-9586
-
-
Mariash, C.N.1
Seelig, S.2
Schwartz, H.L.3
Oppenheimer, J.H.4
-
21
-
-
0036998107
-
Effects of deoxycholate on human colon cancer cells: Apoptosis or proliferation
-
Milovic V, Teller IC, Faust D, Caspary WF, Stein J. Effects of deoxycholate on human colon cancer cells: apoptosis or proliferation. Eur J Clin Invest 32: 29-34, 2002.
-
(2002)
Eur J Clin Invest
, vol.32
, pp. 29-34
-
-
Milovic, V.1
Teller, I.C.2
Faust, D.3
Caspary, W.F.4
Stein, J.5
-
22
-
-
0035859008
-
Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathway in breast cancer cells
-
Niu MY, Menard M, Reed JC, Krajewski S, Pratt MA. Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathway in breast cancer cells. Oncogene 20: 3506-3518, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 3506-3518
-
-
Niu, M.Y.1
Menard, M.2
Reed, J.C.3
Krajewski, S.4
Pratt, M.A.5
-
23
-
-
2342475205
-
Deoxycholic acid activates β-catenin signaling pathway and increases colon cell cancer growth and invasiveness
-
Pai R, Tarnawski AS, Tran T. Deoxycholic acid activates β-catenin signaling pathway and increases colon cell cancer growth and invasiveness. Mol Biol Cell 15: 2156-2163, 2004.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2156-2163
-
-
Pai, R.1
Tarnawski, A.S.2
Tran, T.3
-
24
-
-
0036725044
-
Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited
-
Paumgartner G, Beuers U. Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited. Hepatology 36: 525-531, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 525-531
-
-
Paumgartner, G.1
Beuers, U.2
-
25
-
-
0029094171
-
Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter
-
Pestell RG, Albanese C, Watanabe G, Johnson J, Eklund N, Lastowiecki P, Jameson JL. Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter. J Biol Chem 270: 18301-18308, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 18301-18308
-
-
Pestell, R.G.1
Albanese, C.2
Watanabe, G.3
Johnson, J.4
Eklund, N.5
Lastowiecki, P.6
Jameson, J.L.7
-
26
-
-
0038529807
-
Bcl-2 controls caspase activation following a p53-dependent cyclin D1-induced death signal
-
Pratt MA, Niu MY. Bcl-2 controls caspase activation following a p53-dependent cyclin D1-induced death signal. J Biol Chem 278: 14219-14229, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 14219-14229
-
-
Pratt, M.A.1
Niu, M.Y.2
-
27
-
-
0036288670
-
Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53
-
Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53. Hepatology 36: 39-48, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 39-48
-
-
Qiao, L.1
McKinstry, R.2
Gupta, S.3
Gilfor, D.4
Windle, J.J.5
Hylemon, P.B.6
Grant, S.7
Fisher, P.B.8
Dent, P.9
-
28
-
-
0032525819
-
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
-
Rodrigues CMP, Fan G, Ma X, Kren BT, Steer CJ. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Invest 101: 2790-2799, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 2790-2799
-
-
Rodrigues, C.M.P.1
Fan, G.2
Ma, X.3
Kren, B.T.4
Steer, C.J.5
-
29
-
-
0031950282
-
Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
-
Rodrigues CMP, Fan G, Wong PY, Kren BT, Steer CJ. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol Med 4: 165-178, 1998.
-
(1998)
Mol Med
, vol.4
, pp. 165-178
-
-
Rodrigues, C.M.P.1
Fan, G.2
Wong, P.Y.3
Kren, B.T.4
Steer, C.J.5
-
30
-
-
0032846812
-
Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation
-
Rodrigues CMP, Ma X, Linehan-Stieers C, Fan G, Kren BT, Steer CJ. Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation. Cell Death Differ 6: 842-854, 1999.
-
(1999)
Cell Death Differ
, vol.6
, pp. 842-854
-
-
Rodrigues, C.M.P.1
Ma, X.2
Linehan-Stieers, C.3
Fan, G.4
Kren, B.T.5
Steer, C.J.6
-
31
-
-
0034629291
-
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release
-
Schuler M, Bossy-Wetzel E, Goldstein JC, Fitzgerald P, Green DR. p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J Biol Chem 275: 7337-7342, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 7337-7342
-
-
Schuler, M.1
Bossy-Wetzel, E.2
Goldstein, J.C.3
Fitzgerald, P.4
Green, D.R.5
-
32
-
-
0032539673
-
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
-
Shimizu S, Eguchi Y, Kamiike W, Funahashi Y, Mignon A, Lacronique V, Matsuda H, Tsujimoto Y. Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Natl Acad Sci USA 95: 1455-1459, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1455-1459
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
Funahashi, Y.4
Mignon, A.5
Lacronique, V.6
Matsuda, H.7
Tsujimoto, Y.8
-
33
-
-
0030444208
-
Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E
-
Sofer-Levi Y, Resnitzky D. Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E. Oncogene 13: 2431-2437, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 2431-2437
-
-
Sofer-Levi, Y.1
Resnitzky, D.2
-
34
-
-
25844516609
-
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-β1-induced apoptosis in rat hepatocytes
-
Solá S, Amaral JD, Castro RE, Ramalho RM, Borralho PM, Kren BT, Tanaka H, Steer CJ, Rodrigues CMP. Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-β1-induced apoptosis in rat hepatocytes. Hepatology 42: 925-934, 2005.
-
(2005)
Hepatology
, vol.42
, pp. 925-934
-
-
Solá, S.1
Amaral, J.D.2
Castro, R.E.3
Ramalho, R.M.4
Borralho, P.M.5
Kren, B.T.6
Tanaka, H.7
Steer, C.J.8
Rodrigues, C.M.P.9
-
35
-
-
3142580336
-
Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-β1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes
-
Solá S, Castro RE, Kren BT, Steer CJ, Rodrigues CMP. Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-β1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes. Biochemistry 43: 8429-8438, 2004.
-
(2004)
Biochemistry
, vol.43
, pp. 8429-8438
-
-
Solá, S.1
Castro, R.E.2
Kren, B.T.3
Steer, C.J.4
Rodrigues, C.M.P.5
-
36
-
-
1542467261
-
Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor β1-induced apoptosis of rat hepatocytes
-
Solá S, Ma X, Castro RE, Kren BT, Steer CJ, Rodrigues CMP. Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor β1-induced apoptosis of rat hepatocytes. J Biol Chem 278: 48831-48838, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 48831-48838
-
-
Solá, S.1
Ma, X.2
Castro, R.E.3
Kren, B.T.4
Steer, C.J.5
Rodrigues, C.M.P.6
-
37
-
-
0346363603
-
Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons
-
Sumrejkanchanakij P, Tamamori-Adachi M, Matsunaga Y, Eto K, Ikeda MA. Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons. Oncogene 22: 8723-8730, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 8723-8730
-
-
Sumrejkanchanakij, P.1
Tamamori-Adachi, M.2
Matsunaga, Y.3
Eto, K.4
Ikeda, M.A.5
-
38
-
-
0035895263
-
Ursodiol use is associated with lower prevalence of colonic neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis
-
Tung BY, Emond MJ, Haggitt RC, Bronner MP, Kimmey MB, Kowdley KV, Brentnall TA. Ursodiol use is associated with lower prevalence of colonic neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis. Ann Intern Med 134: 89-95, 2001.
-
(2001)
Ann Intern Med
, vol.134
, pp. 89-95
-
-
Tung, B.Y.1
Emond, M.J.2
Haggitt, R.C.3
Bronner, M.P.4
Kimmey, M.B.5
Kowdley, K.V.6
Brentnall, T.A.7
-
39
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2: 594-604, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
40
-
-
0036917814
-
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: Roles of cyclin D1 and E-cadherin
-
Wali RK, Khare S, Tretiakova M, Cohen G, Nguyen L, Hart J, Wang J, Wen M, Ramaswamy A, Joseph L, Sitrin M, Brasitus T, Bissonnette M. Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. Cancer Epidemiol Biomarkers Prev 11: 1653-1662, 2002.
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 1653-1662
-
-
Wali, R.K.1
Khare, S.2
Tretiakova, M.3
Cohen, G.4
Nguyen, L.5
Hart, J.6
Wang, J.7
Wen, M.8
Ramaswamy, A.9
Joseph, L.10
Sitrin, M.11
Brasitus, T.12
Bissonnette, M.13
-
41
-
-
18144416611
-
The transcriptional targets of p53 in apoptosis control
-
Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 331: 851-858, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 851-858
-
-
Yu, J.1
Zhang, L.2
|