Cholesterol secoaldehyde, an ozonation product of cholesterol, induces amyloid aggregation and apoptosis in murine GT1-7 hypothalamic neurons

Journal of Alzheimer's Disease

Volumn 11, Issue 3, 2007, Pages 261-274

  Sathishkumar, K ^a   Xi, Xiaochun ^b   Martin, Roy ^b   Uppu, Rao M ^a  

^a SOUTHERN UNIVERSITY   (United States)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Amyloid aggregation; Cholesterol secoaldehyde; Neuronal apoptosis; Oxysterols; Ozone; Reactive oxygen species

Indexed keywords

3BETA HYDROXY 5 OXO 5,6 SECOCHOLESTAN 6 AL; ACETYLCYSTEINE; AMYLOID BETA PROTEIN; CASPASE 3; CASPASE 7; DNA FRAGMENT; FIBRILLOGENESIS INHIBITOR; GLUTATHIONE; OXYSTEROL; PHOSPHATIDYLSERINE; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE; TROLOX C; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVITY; HYPOTHALAMUS; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OZONATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; WESTERN BLOTTING;

EID: 34447651132     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2007-11302     Document Type: Article

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