Antiapoptotic cytokines in combination with pegfilgrastim soon after irradiation mitigates myelosuppression in nonhuman primates exposed to high irradiation dose

Experimental Hematology

Volumn 35, Issue 8, 2007, Pages 1172-1181

  Hérodin, Francis ^a   Roy, Laurence ^b   Grenier, Nancy ^a   Delaunay, Christophe ^a   Baugé, Stéphane ^a   Vaurijoux, Aurélie ^b   Grégoire, Eric ^b   Martin, Cécile ^b   Alonso, Antonia ^a   Mayol, Jean François ^a   Drouet, Michel ^a  

^a CENTRE DE RECHERCHES   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; C REACTIVE PROTEIN; CEFALEXIN; FIBRINOGEN; FLT3 LIGAND; GENTAMICIN; INTERLEUKIN 3; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR; THROMBOPOIETIN;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD TRANSFUSION; BONE MARROW BIOPSY; BONE MARROW SUPPRESSION; BURST FORMING UNIT E; CHROMOSOME PAINTING; CHROMOSOME TRANSLOCATION; CLONOGENESIS; COLONY FORMING UNIT GEMM; COLONY FORMING UNIT GM; CONTROLLED STUDY; DOSIMETRY; DRUG EFFICACY; DRUG SAFETY; EMERGENCY ANTIAPOPTOTIC CYTOKINE THERAPY; EXPERIMENTAL THERAPY; FLUORESCENCE IN SITU HYBRIDIZATION; INFLAMMATION; LYMPHOCYTE CULTURE; LYMPHOCYTOPENIA; MACACA; MALE; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; STATISTICAL ANALYSIS; THROMBOCYTOPENIA; WHOLE BODY RADIATION;

ANIMALS; APOPTOSIS; BLOOD PLATELETS; BONE MARROW; CHROMOSOME ABERRATIONS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, RADIATION; FILGRASTIM; HEMATOPOIESIS; HUMANS; INFLAMMATION; LEUKOCYTES; LYMPHOCYTES; MACACA FASCICULARIS; MALE; RECOMBINANT PROTEINS;

PRIMATES;

EID: 34447641786     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.04.017     Document Type: Article

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