Acute Radiation Injury: Contingency Planning for Triage, Supportive Care, and Transplantation

Biology of Blood and Marrow Transplantation

Volumn 12, Issue 6, 2006, Pages 672-682

  Weisdorf, Daniel ^a   Chao, Nelson ^b   Waselenko, Jamie K ^c   Dainiak, Nicholas ^d   Armitage, James O ^e   McNiece, Ian ^f   Confer, Dennis ^g  

^a UNIVERSITY OF MINNESOTA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c SARAH CANNON RESEARCH INSTITUTE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^f Johns Hopkins Singapore   (Singapore)

^g NATIONAL MARROW DONOR PROGRAM   (United States)

Author keywords

Contingency planning; Radiation injury; Transplantation

Indexed keywords

ACICLOVIR; AMPHOTERICIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CASPOFUNGIN; CYTOKINE; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 1; INTERLEUKIN 11; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR; THROMBOPOIETIN; VORICONAZOLE;

ACUTE DISEASE; AMBLYOPIA; ARTICLE; BONE MARROW SUPPRESSION; BONE PAIN; CHILL; CLINICAL FEATURE; CLINICAL TRIAL; DATA ANALYSIS; DEHYDRATION; DOSIMETRY; EMERGENCY HEALTH SERVICE; ERYTHEMA; EXFOLIATIVE DERMATITIS; FEVER; HEALTH CARE PLANNING; HEMATOLOGIC DISEASE; HEMATOLOGY; HUMAN; HYPOTENSION; INTRAOCULAR HEMORRHAGE; MEDICAL SPECIALIST; NONHUMAN; ONCOLOGY; OPPORTUNISTIC INFECTION; PANCYTOPENIA; PARESTHESIA; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION SICKNESS; SKIN DISCOLORATION; STEM CELL TRANSPLANTATION; TREATMENT PLANNING; VICTIM;

ANEMIA, APLASTIC; BIOTERRORISM; BLOOD CELL COUNT; EMERGENCIES; ENVIRONMENTAL EXPOSURE; GROWTH SUBSTANCES; HUMANS; MODELS, BIOLOGICAL; MYELODYSPLASTIC SYNDROMES; NUCLEAR WARFARE; RADIATION INJURIES; RADIOACTIVE FALLOUT; STEM CELL TRANSPLANTATION; TRIAGE;

EID: 33646805739     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2006.02.006     Document Type: Article

References (40)

1. Dainiak N. The evolving role of hematopoietic cell transplantation in radiation injury. potentials and limitations. Br J Radiol 27 (2005) 169-174
2. Nagayama H., Ooi J., Tomonari A., et al. Severe immune dysfunction after lethal neutron irradiation in a JCO nuclear facility accident victim. Int J Hematol 76 (2002) 157-164
3. Waselenko J.K., MacVittie T.J., Blakely W.F., et al. Medical management of the acute radiation syndrome. recommendations of the Strategic National Stockpile Radiation Working Group. Ann Intern Med 140 (2004) 1037-1051
4. Baranov A., Gale R.P., Guskova A., et al. Bone marrow transplantation after the Chernobyl nuclear accident. N Eng J Med 321 (1989) 205-212
5. Fliedner T.M., Dorr H.D., and Meineke V. Multi-organ involvement as a pathogenetic principle of the radiation syndromes. a study involving 110 case histories documented in SEARCH and classified as the bases of haematopoietic indicators of effect. Br J Radiol 78 (2005) 1-8
6. Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 30; (2002) 513-528
7. Cerveny T.J., MacVittie T.J., and Young R.W. Acute radiation syndrome in humans. In: Cerveny T.J. (Ed). Medical Consequences of Nuclear Warfare (1989), Armed Forces Radiobiology Research Institute, Bethesda, MD Alexandria, VA: Defense Nuclear Agency/Falls Church, VA: TMM Publications, Office of the Surgeon General
8. Hall E.J. Acute effects of total-body irradiation. In: Hall E.J. (Ed). Radiobiology for the Radiologist (2000), Lippincott Williams & Wilkins, Philadelphia 124-135
9. Vorobiev A.I. Acute radiation disease and biological dosimetry in 1993. Stem Cells 15 (1997) 269-274
10. Hughes W.T., Armstrong D., Bodey G.P., et al. 2002 Guidelines for the use of antimicrobial agents in neutropenic patients with cancer. Clin Infect Dis 34 (2002) 730-751
11. Barabanova A.V. Acute radiation syndrome with cutaneous syndrome. In: Ricks R.C., Berger M.E., and O'Hara F. (Eds). The Medical Basis for Radiation Accident Preparedness. The Clinical Care of Victims (2002), Parthenon Publishing Group, Boca Raton, FL 217-224
12. van Bekkum D. Radiation sensitivity of the hematopoietic stem cell. Radiat Res 128 (1991) 4-9
13. Inoue T., Hirabayashai Y., Mitsui H., et al. Survival of spleen colony-forming units (CFU-S) of irradiated bone marrow cells in mice. evidence for the existence of a radiosensitive subfraction. Exp Hematol 23 (1995) 1296-1300
14. Dainiak N., Waselenko J.K., Armitage J.O., MacVittie T.J., and Farese A.M. The hematologist and radiation casualties. Hematology (Am Soc Hematol Educ Program) (2003) 473-496
15. Waselenko J.K., Armitage J.O., and Dainiak N. Treatment of radiation injury in the adult. UpToDate (2005)
16. Elliott T.B., Brook I., and Stiefel S.M. Quantitative study of wound infection in irradiated mice. Int J Radiat Biol 58 (1990) 341-350
17. Kaplan H.S., Speck R.S., and Jawetz E. Impairment of antimicrobial defense following total body irradiation of mice. J Lab Clin Med 40 (1952) 682-691
18. Brook I., and Ledney G.E. Quinolone therapy in the prevention of endogenous and exogenous infection after irradiation. J Antimicrob Chemother 33 (1994) 777-784
19. Brook I., Elliott T.B., and Ledney G.D. Quinolone therapy of Klebsiella pneumoniae sepsis following irradiation. comparison of pefloxacin, ciprofloxacin, and ofloxacin. Radiat Res 122 (1990) 215-217
20. Brook I., Elliott T.B., Ledney G.D., and Knudson G.B. Management of postirradiation sepsis. Mil Med 167 (2002) 105-106
21. Cruciani M., Malena M., Bosco O., Nardi S., Serpelloni G., and Mengoli C. Reappraisal with meta-analysis of the addition of Gram-positive prophylaxis to fluoroquinolone in neutropenic patients. J Clin Oncol 21 (2003) 4127-4137
22. Engels E.A., Lau J., and Barza M. Efficacy of quinolone prophylaxis in neutropenic cancer patients. a meta-analysis. J Clin Oncol 16 (1998) 1179-1187
23. Slavin M.A., Osborne B., Adams R., et al. Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation-a prospective, randomized, double-blind study. J Infect Dis 171 (1995) 1545-1552
24. Goodman J.L., Winston D.J., Greenfield R.A., et al. A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation. N Engl J Med 326 (1992) 845-851
25. Hughes W.T. Use of antimicrobial agents for treatment of infection in the neutropenic immunocompromised patient. In: Ricks R.C., Berger M.E., and O'Hara F. (Eds). The Medical Basis for Radiation Accident Preparedness. The Clinical Care of Victims (2002), Parthenon Publishing Group, Boca Raton, FL 117-129
26. Densow D., Kindler H., Baranov A.E., Tibken B., Hofer E.P., and Fliedner T.M. Criteria for the selection of radiation accident victims for stem cell transplantation. Stem Cells 15 (1997) 287-297
27. Maekawa K. Overview of medical care for highly exposed victims in the Tokaimura Accident. In: Ricks R.C., Berger M.E., and O'Hara F. (Eds). The Medical Basis for Radiation Accident Preparedness. The Clinical Care of Victims (2002), Parthenon Publishing Group, Boca Raton, FL 313-318
28. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Biol Blood Marrow Transplant. 2000;6:659-733.
29. Tanikawa S., Nose M., Aoki Y., Tsuneoka K., Shikita M., and Nara N. Effects of recombinant human granulocyte colony-stimulating factor on the hematologic recovery and survival of irradiated mice. Blood 76 (1990) 445-449
30. Hosoi Y., Kurishita A., Ono T., and Sakamoto K. Effect of recombinant human granulocyte colony-stimulating factor on survival of lethally irradiated mice. Acta Oncol 31 (1992) 59-63
31. Nothdurft W., Kreja L., and Selig C. Acceleration of hemopoietic recovery in dogs after treatment extended-field partial-body irradiation by treatment with colony-stimulating factors. rhG-CSF and rhGM-CSF. Int J Radiat Oncol Biol Phys 37 (1997) 1145-1154
32. Farese A.M., Hunt P., Grab L.B., and MacVittie T.J. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia. J Clin Invest 97 (1996) 2145-2151
33. Hao J., Sun L., Huang H., et al. Effects of recombinant human interleukin 11 on thrombocytopenia and neutropenia in irradiated rhesus monkeys. Radiat Res 162 (2004) 157-163
34. Shibuya K., Akahori H., Takahashi K., Tahara E., Kato T., and Miyazaki. Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice. Blood 91 (1998) 37-45
35. Zsebo K.M., Smith K.A., Hartley C.A., et al. Radioprotection of mice by recombinant stem cells factor. Proc Natl Acad Sci USA 89 (1992) 9464-9468
36. Neta R., Oppenheim J.J., and Douches S.D. Interdependence of the radioprotective effects of human recombinant IL-1, TNF, G-CSF and murine recombinant GM-CSF. J Immunol 140 (1998) 108-111
37. Neta R., Oppenheim J.J., Wang J.M., Snapper C.M., Moorman M.A., and Dubois C.M. Synergy of IL-1 and stem cell factor in radioprotection of mice is associated with IL-1 up-regulation of mRNA and protein expression for c-kit on bone marrow cells. J Immunol 153 (1994) 1536-1543
38. Waddick K.G., Song C.W., Souza L., and Uchun F.M. Comparative analysis of the in vivo radioprotective effects of recombinant granulocyte colony-stimulating factor (G-CSF), recombinant granulocyte-macrophage CSF, and their combination. Blood 77 (1991) 2364-2471
39. Cairo M.S., Plunkett J.M., Nguyen A., Schendel P., and van de Ven C. Effect of interleukin-11 with and without granulocyte colony-stimulating factor on in vivo neonatal rat hematopoiesis. induction of neonatal thrombocytosis by interleukin-11 and synergistic enhancement of neutropenia by interleukin-11 + granulocyte colony-stimulating factor. Pediatr Res 34 (1993) 56-61
40. Herodin F., and Drouet M. Cytokine-based treatment of accidentally irradiated victims and new approaches. Exp Hematol 33 (2005) 1071-1080