-
1
-
-
33749027737
-
Can pharmacogenetics help rescue drugs withdrawn from the market?
-
Shah RR. Can pharmacogenetics help rescue drugs withdrawn from the market? Pharmacogenomics 2006;7:889-908.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 889-908
-
-
Shah, R.R.1
-
2
-
-
2542447230
-
Techniques: Reporter mice - a new way to look at drug action
-
Maggi A, Ottobrini L, Biserni A, Lucignani G, Ciana P. Techniques: reporter mice - a new way to look at drug action. Trends Pharmacol Sci 2004;25:337-42.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 337-342
-
-
Maggi, A.1
Ottobrini, L.2
Biserni, A.3
Lucignani, G.4
Ciana, P.5
-
3
-
-
32544457669
-
Molecular imaging: A new way to study molecular processes in vivo
-
Ottobrini L, Ciana P, Biserni A, Lucignani G, Maggi A. Molecular imaging: a new way to study molecular processes in vivo. Mol Cell Endocrinol 2006;246:69-75.
-
(2006)
Mol Cell Endocrinol
, vol.246
, pp. 69-75
-
-
Ottobrini, L.1
Ciana, P.2
Biserni, A.3
Lucignani, G.4
Maggi, A.5
-
4
-
-
34447529720
-
-
US Code of Federal Regulations 21CFR § 314.500-60.
-
US Code of Federal Regulations 21CFR § 314.500-60.
-
-
-
-
5
-
-
33644995190
-
Molecular imaging: What can be used today
-
Jager PL, de Korte MA, Lub-de Hooge MN, van Waarde A, Koopmans KP, Perik PJ et al. Molecular imaging: what can be used today. Cancer Imaging 2005;5 Spec No A:S27-32.
-
(2005)
Cancer Imaging
, vol.5
, Issue.SPEC A
-
-
Jager, P.L.1
de Korte, M.A.2
Lub-de Hooge, M.N.3
van Waarde, A.4
Koopmans, K.P.5
Perik, P.J.6
-
6
-
-
0041878843
-
Usefulness of chest single photon emission computed tomography with technetium-99m methoxyisobutylisonitrile to predict taxol based chemotherapy response in advanced non-small cell lung cancer
-
Shih CM, Hsu WH, Huang WT, Wang JJ, Ho ST, Kao A. Usefulness of chest single photon emission computed tomography with technetium-99m methoxyisobutylisonitrile to predict taxol based chemotherapy response in advanced non-small cell lung cancer. Cancer Lett 2003;199:99-105.
-
(2003)
Cancer Lett
, vol.199
, pp. 99-105
-
-
Shih, C.M.1
Hsu, W.H.2
Huang, W.T.3
Wang, J.J.4
Ho, S.T.5
Kao, A.6
-
8
-
-
0035202667
-
The RECIST (Response Evaluation Criteria in Solid Tumors) criteria: Implications for diagnostic radiologists
-
Padhani AR, Ollivier L. The RECIST (Response Evaluation Criteria in Solid Tumors) criteria: implications for diagnostic radiologists. Br J Radiol 2001;74:983-6.
-
(2001)
Br J Radiol
, vol.74
, pp. 983-986
-
-
Padhani, A.R.1
Ollivier, L.2
-
9
-
-
33646711641
-
Imaging outcomes and their role in determining outcomes in ostcoarthritis and rheumatoid arthritis
-
Hunter DJ, Conaghan PG. Imaging outcomes and their role in determining outcomes in ostcoarthritis and rheumatoid arthritis. Curr Opin Rheumatol 2006;18:157-62.
-
(2006)
Curr Opin Rheumatol
, vol.18
, pp. 157-162
-
-
Hunter, D.J.1
Conaghan, P.G.2
-
11
-
-
14944380168
-
Reporter mice and drug discovery and development
-
Maggi A, Ciana P. Reporter mice and drug discovery and development. Nat Rev Drug Discov 2005;4:249-55.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 249-255
-
-
Maggi, A.1
Ciana, P.2
-
12
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
Bruning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell 1997;88:561-72.
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Bruning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
13
-
-
0026562404
-
-
Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256:668-70. Erratum in: Science 1992;256:1114.
-
Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256:668-70. Erratum in: Science 1992;256:1114.
-
-
-
-
14
-
-
0036558204
-
Pharmaceutical use of mouse models humanized for the xenobiotic receptor
-
Xie W, Evans RM. Pharmaceutical use of mouse models humanized for the xenobiotic receptor. Drug Discov Today 2002;7:509-15.
-
(2002)
Drug Discov Today
, vol.7
, pp. 509-515
-
-
Xie, W.1
Evans, R.M.2
-
15
-
-
0037234105
-
In vivo imaging of transcriptionally active estrogen receptors
-
Ciana P, Raviscioni M, Mussi P, Vegeto E, Que I, Parker MG et al. In vivo imaging of transcriptionally active estrogen receptors. Nat Med 2003;9:82-6.
-
(2003)
Nat Med
, vol.9
, pp. 82-86
-
-
Ciana, P.1
Raviscioni, M.2
Mussi, P.3
Vegeto, E.4
Que, I.5
Parker, M.G.6
-
16
-
-
33750952902
-
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland
-
Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS et al. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A 2006;103:16716-21.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16716-16721
-
-
Mussi, P.1
Liao, L.2
Park, S.E.3
Ciana, P.4
Maggi, A.5
Katzenellenbogen, B.S.6
-
17
-
-
0034953302
-
Engineering of a mouse for the in vivo profiling of estrogen receptor activity
-
Ciana P, Di Luccio G, Belcredito S, Pollio G, Vegeto E, Tatangelo L et al. Engineering of a mouse for the in vivo profiling of estrogen receptor activity. Mol Endocrinol 2001;15:1104-13.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1104-1113
-
-
Ciana, P.1
Di Luccio, G.2
Belcredito, S.3
Pollio, G.4
Vegeto, E.5
Tatangelo, L.6
-
18
-
-
0036467996
-
insulators: Many functions, many mechanisms
-
West AG, Gaszner M, Felsenfeld G. insulators: many functions, many mechanisms. Genes Dev 2002;16:271-88.
-
(2002)
Genes Dev
, vol.16
, pp. 271-288
-
-
West, A.G.1
Gaszner, M.2
Felsenfeld, G.3
-
19
-
-
26644466986
-
A dual-fight reporter system to determine the efficiency of protein-protein interactions in mammalian cells
-
Nasim MT, Trembath RC. A dual-fight reporter system to determine the efficiency of protein-protein interactions in mammalian cells. Nucleic Acids Res 2005;33:e66.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Nasim, M.T.1
Trembath, R.C.2
-
21
-
-
0023124097
-
Firefly luciferase gene: Structure and expression in mammalian cells
-
De VetJR, Wood KV, DeLuca M, Helinski DR, Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol 1987;7:725-37.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 725-737
-
-
VetJR, D.1
Wood, K.V.2
DeLuca, M.3
Helinski, D.R.4
Subramani, S.5
-
22
-
-
0035044158
-
A unique charge-coupled device/xenon arc lamp based imaging system for the accurate detection and quantitation of multicolour fluorescence
-
Spibey CA, Jackson P, Herick K. A unique charge-coupled device/xenon arc lamp based imaging system for the accurate detection and quantitation of multicolour fluorescence. Electrophoresis 2001;22:829-36.
-
(2001)
Electrophoresis
, vol.22
, pp. 829-836
-
-
Spibey, C.A.1
Jackson, P.2
Herick, K.3
-
23
-
-
0034981261
-
In utero delivery of adeno-associated viral vectors: Intraperitoneal gene trarisfer produces long-term expression
-
Lipshutz GS, Gruber CA, Cao Y, Hardy J, Contag CH, Gaensler KM. In utero delivery of adeno-associated viral vectors: intraperitoneal gene trarisfer produces long-term expression. Mol Ther 2001;3:284-92.
-
(2001)
Mol Ther
, vol.3
, pp. 284-292
-
-
Lipshutz, G.S.1
Gruber, C.A.2
Cao, Y.3
Hardy, J.4
Contag, C.H.5
Gaensler, K.M.6
-
24
-
-
0035957085
-
The role of active site residue arginine 218 in firefly luciferase bioluminescence
-
Branchini BR, Magyar RA, Murtiashaw MH, Portier NC. The role of active site residue arginine 218 in firefly luciferase bioluminescence. Biochemistry 2001;40:2410-8.
-
(2001)
Biochemistry
, vol.40
, pp. 2410-2418
-
-
Branchini, B.R.1
Magyar, R.A.2
Murtiashaw, M.H.3
Portier, N.C.4
-
25
-
-
0032858233
-
Site-directed mutagenesis of firefly luciferase active site amino acids: A proposed model for bioluminescence color
-
Branchini BR, Magyar RA, Murtiashaw MH, Anderson SM, Helgerson LC, Zimmer M. Site-directed mutagenesis of firefly luciferase active site amino acids: a proposed model for bioluminescence color. Biochemistry 1999;38:13223-30.
-
(1999)
Biochemistry
, vol.38
, pp. 13223-13230
-
-
Branchini, B.R.1
Magyar, R.A.2
Murtiashaw, M.H.3
Anderson, S.M.4
Helgerson, L.C.5
Zimmer, M.6
-
26
-
-
0017582130
-
Purification and properties of Renilla reniformis luciferase
-
Matthews JC, Hod K, Cormier MJ. Purification and properties of Renilla reniformis luciferase. Biochemistry 1977;16:85-91.
-
(1977)
Biochemistry
, vol.16
, pp. 85-91
-
-
Matthews, J.C.1
Hod, K.2
Cormier, M.J.3
-
27
-
-
33748101201
-
Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output
-
Loening AM, Fenn TD, Wu AM, Gambhir SS. Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output. Protein Eng Des Sel 2006;19:391-400.
-
(2006)
Protein Eng Des Sel
, vol.19
, pp. 391-400
-
-
Loening, A.M.1
Fenn, T.D.2
Wu, A.M.3
Gambhir, S.S.4
-
28
-
-
33748763812
-
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors
-
Venisnik KM, Olafsen T, Loening AM, Iyer M, Gambhir SS, Wu AM. Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors. Protein Eng Des Sel 2006;19:453-60.
-
(2006)
Protein Eng Des Sel
, vol.19
, pp. 453-460
-
-
Venisnik, K.M.1
Olafsen, T.2
Loening, A.M.3
Iyer, M.4
Gambhir, S.S.5
Wu, A.M.6
-
29
-
-
0037039437
-
Optical imaging of Renilla luciferase reporter gene expression in living mice
-
Bhauniik S, Gambhir SS. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci U S A 2002;99:377-82.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 377-382
-
-
Bhauniik, S.1
Gambhir, S.S.2
-
30
-
-
0002468820
-
The colors of firefly bioluminescence: Enzyme configuration and species specificity
-
Seliger HH, McElroy WD. The colors of firefly bioluminescence: enzyme configuration and species specificity. Proc Natl Acad Sci U S A 1964;52:75-81.
-
(1964)
Proc Natl Acad Sci U S A
, vol.52
, pp. 75-81
-
-
Seliger, H.H.1
McElroy, W.D.2
-
31
-
-
0033614782
-
Cloning, sequence analysis, and expression of active Phrixothrix railroad-worms luciferases: Relationship between bioluminescence spectra and primary structures
-
Viviani VR, Bechara EJ, Ohmiya Y. Cloning, sequence analysis, and expression of active Phrixothrix railroad-worms luciferases: relationship between bioluminescence spectra and primary structures. Biochemistry 1999;38:8271-9.
-
(1999)
Biochemistry
, vol.38
, pp. 8271-8279
-
-
Viviani, V.R.1
Bechara, E.J.2
Ohmiya, Y.3
-
32
-
-
4544366731
-
Improved expression of novel red- and green-emitting luciferases of Phrixothrix railroad worms in mammalian cells
-
Nakajima Y, Kimura T, Suzuki C, Ohmiya Y. Improved expression of novel red- and green-emitting luciferases of Phrixothrix railroad worms in mammalian cells. Biosci Biotechnol Biochem 2004;68:948-51.
-
(2004)
Biosci Biotechnol Biochem
, vol.68
, pp. 948-951
-
-
Nakajima, Y.1
Kimura, T.2
Suzuki, C.3
Ohmiya, Y.4
-
33
-
-
14044250981
-
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
-
Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 2005;11:435-43.
-
(2005)
Mol Ther
, vol.11
, pp. 435-443
-
-
Tannous, B.A.1
Kim, D.E.2
Fernandez, J.L.3
Weissleder, R.4
Breakefield, X.O.5
-
34
-
-
12944327946
-
Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases
-
Yang M, Baranov E, Jiang P, Sun FX, Li XM, Li L et al. Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A 2000;97:1206-11.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1206-1211
-
-
Yang, M.1
Baranov, E.2
Jiang, P.3
Sun, F.X.4
Li, X.M.5
Li, L.6
-
35
-
-
25844461626
-
The multiple uses of fluorescent proteins to visualize cancer in vivo
-
Hoffman RM. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 2005;5:796-806.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 796-806
-
-
Hoffman, R.M.1
-
36
-
-
0034710920
-
Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral
-
Baird GS, Zacharias DA, Tsien RY. Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral. Proc Natl Acad Sci U S A 2000;97:11984-9.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 11984-11989
-
-
Baird, G.S.1
Zacharias, D.A.2
Tsien, R.Y.3
-
37
-
-
0036138545
-
-
Bevis BJ, Glick BS. Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed). Nat Biotechnol 2002;20:83-7. Erratum in: Nat Biotechnol 2002;20:1159.
-
Bevis BJ, Glick BS. Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed). Nat Biotechnol 2002;20:83-7. Erratum in: Nat Biotechnol 2002;20:1159.
-
-
-
-
38
-
-
11144267737
-
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
-
Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AF, Tsien RY. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 2004;22:1567-72.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1567-1572
-
-
Shaner, N.C.1
Campbell, R.E.2
Steinbach, P.A.3
Giepmans, B.N.4
Palmer, A.F.5
Tsien, R.Y.6
-
39
-
-
23944469298
-
Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
-
Bullok K, Piwnica-Worms D. Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. J Med Chem 2005;48:5404-7.
-
(2005)
J Med Chem
, vol.48
, pp. 5404-5407
-
-
Bullok, K.1
Piwnica-Worms, D.2
-
40
-
-
33750971995
-
In vivo near-infrared fluorescence imaging of mitegriin alphavbeta3 in an orthotopic glioblastoma model
-
Hsu AR, Hou LC, Veeravagu A, Greve JM, Vogel H, Tse V et al. In vivo near-infrared fluorescence imaging of mitegriin alphavbeta3 in an orthotopic glioblastoma model. Mol Imaging Biol 2006;8:315-23.
-
(2006)
Mol Imaging Biol
, vol.8
, pp. 315-323
-
-
Hsu, A.R.1
Hou, L.C.2
Veeravagu, A.3
Greve, J.M.4
Vogel, H.5
Tse, V.6
-
41
-
-
0012392952
-
Semiconductor nanocrystals as fluorescent biological labels
-
Bruchez M Jr, Moronne M, Gin P, Weiss S, Alivisatos AP. Semiconductor nanocrystals as fluorescent biological labels. Science 1998;281:2013-6.
-
(1998)
Science
, vol.281
, pp. 2013-2016
-
-
Bruchez Jr, M.1
Moronne, M.2
Gin, P.3
Weiss, S.4
Alivisatos, A.P.5
-
42
-
-
0344494018
-
Biocompatible fluorescent nanocrystals for immunolabeling of membrane proteins and cells
-
Sukhanova A, DevyJ, Venteo L, Kaplan H, Artemyev M, Oleinikov V et al. Biocompatible fluorescent nanocrystals for immunolabeling of membrane proteins and cells. Anal Biochem 2004;324:60-7.
-
(2004)
Anal Biochem
, vol.324
, pp. 60-67
-
-
Sukhanova, A.1
Devy, J.2
Venteo, L.3
Kaplan, H.4
Artemyev, M.5
Oleinikov, V.6
-
43
-
-
19944433260
-
Quantum dots for live cells, in vivo imaging, and diagnostics
-
Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 2005;307:538-44.
-
(2005)
Science
, vol.307
, pp. 538-544
-
-
Michalet, X.1
Pinaud, F.F.2
Bentolila, L.A.3
Tsay, J.M.4
Doose, S.5
Li, J.J.6
-
44
-
-
0842287342
-
Probing the cytotoxicity of semiconductor quantum dots
-
Derfus AM, Chan WCW, Bhatia SN. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 2004;4:11-8.
-
(2004)
Nano Lett
, vol.4
, pp. 11-18
-
-
Derfus, A.M.1
Chan, W.C.W.2
Bhatia, S.N.3
-
45
-
-
33644854853
-
Self-illuminating quantum dot conjugates for in vivo imaging
-
So MK, Xu C, Loening AM, Gambhir SS, Rao J. Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol 2006;24:339-43.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 339-343
-
-
So, M.K.1
Xu, C.2
Loening, A.M.3
Gambhir, S.S.4
Rao, J.5
-
46
-
-
28744450683
-
Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer
-
De A, Gambhir SS. Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer. FASEB J 2005;19:2017-9.
-
(2005)
FASEB J
, vol.19
, pp. 2017-2019
-
-
De, A.1
Gambhir, S.S.2
-
47
-
-
0345060866
-
Dualcolor fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells
-
Yang M, Li L, Jiang P, Moossa AR, Penman S, Hoffman RM. Dualcolor fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells. Proc Natl Acad Sci U S A 2003;100:14259-62.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14259-14262
-
-
Yang, M.1
Li, L.2
Jiang, P.3
Moossa, A.R.4
Penman, S.5
Hoffman, R.M.6
-
48
-
-
0034486139
-
Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging
-
Rehemtulla A, Stegman ID, Cardozo SJ, Gupta S, Hall DE, Contag CH et al. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia 2000;2:491-5.
-
(2000)
Neoplasia
, vol.2
, pp. 491-495
-
-
Rehemtulla, A.1
Stegman, I.D.2
Cardozo, S.J.3
Gupta, S.4
Hall, D.E.5
Contag, C.H.6
-
49
-
-
0037444158
-
Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice
-
Ray P, Wu AM, Gambhir SS. Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Res 2003;63:1160-5.
-
(2003)
Cancer Res
, vol.63
, pp. 1160-1165
-
-
Ray, P.1
Wu, A.M.2
Gambhir, S.S.3
-
50
-
-
1242338786
-
Imaging tri-fusion multimodality reporter gene expression in living subjects
-
Ray P, De A, Min JJ, Tsien RY, Gambhir SS. Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 2004;64:1323-30.
-
(2004)
Cancer Res
, vol.64
, pp. 1323-1330
-
-
Ray, P.1
De, A.2
Min, J.J.3
Tsien, R.Y.4
Gambhir, S.S.5
-
51
-
-
23844463303
-
Micro-SPECT combined with 3D optical imaging. Nuclear Science Symposium Conference Record
-
22 Oct
-
Tsyganov EN, Antich PP, Kulkarni PV, Mason RP, Parkey RW, Seliuonine SY et al. Micro-SPECT combined with 3D optical imaging. Nuclear Science Symposium Conference Record, 2004 IEEE, 5th vol., 16-22 Oct. 2004.p.3275-9.
-
(2004)
2004 IEEE, 5th
, vol.16
, pp. 3275-3279
-
-
Tsyganov, E.N.1
Antich, P.P.2
Kulkarni, P.V.3
Mason, R.P.4
Parkey, R.W.5
Seliuonine, S.Y.6
|