Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model

Eukaryotic Cell

Volumn 6, Issue 7, 2007, Pages 1130-1136

  Meléndez López, Samuel G ^a   Herdman, Scott ^a   Hirata, Ken ^a   Choi, Min Ho ^b   Choe, Youngchool ^c   Craik, Charles ^c   Caffrey, Conor R ^c   Hansell, Elisabeth ^c   Chávez Munguía, Bibiana ^d   Yen, Ting Chen ^e   Roush, William R ^e   McKerrow, James ^c   Eckmann, Lars ^a   Guo, Jianhua ^f   Stanley Jr , Samuel L ^f   Reed, Sharon L ^a,g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Seoul National University College of Medicine   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d DEPARTAMENTO DE FÍSICA   (Mexico)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UCSD MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE I; CYSTEINE PROTEINASE INHIBITOR; DIVINYL SULFONE; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN; SULFONE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL; ARTICLE; CHEMISTRY; COLON; DISEASE MODEL; ENTAMOEBA HISTOLYTICA; ENZYME ACTIVATION; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOUSE; MOUSE MUTANT; PARASITOLOGY; PATHOGENICITY; PATHOLOGY; PH; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN FOLDING; XENOGRAFT;

ANIMALS; COLON; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; ENTAMOEBA HISTOLYTICA; ENZYME ACTIVATION; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, SCID; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SULFONES; TRANSPLANTATION, HETEROLOGOUS; VIRULENCE FACTORS;

ENTAMOEBA HISTOLYTICA; ESCHERICHIA COLI; PROTOZOA;

EID: 34447576973     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00094-07     Document Type: Article

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