-
2
-
-
0032694577
-
Metabonomics": Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson, J. K., Lindon, J. C. and Holmes, E.: "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999, 29, 1181-1189.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
3
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
Nicholson, J. K., Connelly, J., Lindon, J. C. and Holmes, E.: Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 2002, 1, 153-161.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
4
-
-
0036629243
-
Toxicogenomics: A new revolution in drug safety
-
Castle, A. L., Carver, M. P. and Mendrick, D. L.: Toxicogenomics: a new revolution in drug safety. Drug Discovery Today, 2002, 7, 728-736.
-
(2002)
Drug Discovery Today
, vol.7
, pp. 728-736
-
-
Castle, A.L.1
Carver, M.P.2
Mendrick, D.L.3
-
5
-
-
0037011279
-
New 'ome' in town
-
Henry, C. M. New 'ome' in town. Chem. Eng. News 2002, 80, 66-70.
-
(2002)
Chem. Eng. News
, vol.80
, pp. 66-70
-
-
Henry, C.M.1
-
6
-
-
0037225665
-
Proton nuclear magnetic resonance spectroscopy of body fluids in the field of inborn errors of metabolism
-
Moolenaar, S. H., Engelke, U. F. H., Wevers, R.A.: Proton nuclear magnetic resonance spectroscopy of body fluids in the field of inborn errors of metabolism. Ann. Clin. Biochem. 2003, 40, 16-24.
-
(2003)
Ann. Clin. Biochem
, vol.40
, pp. 16-24
-
-
Moolenaar, S.H.1
Engelke, U.F.H.2
Wevers, R.A.3
-
7
-
-
0030513719
-
A spectroscopic approach to lipoprotein subclass analysis
-
Otvos, J., Jeyarajah, E. and Bennett, D.: A spectroscopic approach to lipoprotein subclass analysis. J. Clin. Ligand Assay 1996, 19, 184-189.
-
(1996)
J. Clin. Ligand Assay
, vol.19
, pp. 184-189
-
-
Otvos, J.1
Jeyarajah, E.2
Bennett, D.3
-
8
-
-
0036913503
-
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H NMRbased metabonomics
-
Brindle, J. T., Antti, H., Holmes, E., Tranter, G., Nicholson, J. K., Bethell, H. W. L., Clarke, S., Schofield, P. M., Mckilligin, E., Mosedale, D. E., Granger, D. J.: Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H NMRbased metabonomics. Nat. Med. 2002, 8, 1439-1444.
-
(2002)
Nat. Med
, vol.8
, pp. 1439-1444
-
-
Brindle, J.T.1
Antti, H.2
Holmes, E.3
Tranter, G.4
Nicholson, J.K.5
Bethell, H.W.L.6
Clarke, S.7
Schofield, P.M.8
Mckilligin, E.9
Mosedale, D.E.10
Granger, D.J.11
-
9
-
-
0031949067
-
Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins
-
Beckwith-Hall, B. M., Nicholson, J. K., Nicholls, A., Foxall, P. J. D., Lindon, J. C., Connor, S. C., Abdi, M., Connelly, J. and Holmes, E.: Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins. Chem. Res. Toxicol. 1998, 11, 260-272.
-
(1998)
Chem. Res. Toxicol
, vol.11
, pp. 260-272
-
-
Beckwith-Hall, B.M.1
Nicholson, J.K.2
Nicholls, A.3
Foxall, P.J.D.4
Lindon, J.C.5
Connor, S.C.6
Abdi, M.7
Connelly, J.8
Holmes, E.9
-
10
-
-
7344256122
-
Development of a model for classification of toxin-induced lesions using 1H-NMR spectroscopy of urine combined with pattern recognition
-
Holmes, E., Nicholls, A. W., Lindon, J. C., Ramos, S., Spraul, M., Neidig, P., Connor, S. C., Connelly, J., Damment, S. J. P., Hasleden, J. N. and Nicholson, J. K.: Development of a model for classification of toxin-induced lesions using 1H-NMR spectroscopy of urine combined with pattern recognition. NMR in Biomedicine, 1998, 11, 1-10.
-
(1998)
NMR in Biomedicine
, vol.11
, pp. 1-10
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
Ramos, S.4
Spraul, M.5
Neidig, P.6
Connor, S.C.7
Connelly, J.8
Damment, S.J.P.9
Hasleden, J.N.10
Nicholson, J.K.11
-
11
-
-
0034634448
-
An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: Application to the C57BL10J and Alpk:ApfCD mouse
-
Gavaghan, C. L., Holmes, E., Lenz, E., Wilson, I. D. and Nicholson, J. K.: An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse. FEBS Lett. 2000, 484, 169-174.
-
(2000)
FEBS Lett.
, vol.484
, pp. 169-174
-
-
Gavaghan, C.L.1
Holmes, E.2
Lenz, E.3
Wilson, I.D.4
Nicholson, J.K.5
-
12
-
-
0035160371
-
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
-
Raamsdonk, L. M., Teusink, B., Broadhurst, D., Zhang, N., Hayes, A., Walsh, M. C., Berden, J. A., Brindle, K. M., Kell, D. B., Rowland, J. J., Westerhoff, H. V., van Dam, K., Oliver, S. G.: A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat. Biotech. 2001, 19, 45-50.
-
(2001)
Nat. Biotech.
, vol.19
, pp. 45-50
-
-
Raamsdonk, L.M.1
Teusink, B.2
Broadhurst, D.3
Zhang, N.4
Hayes, A.5
Walsh, M.C.6
Berden, J.A.7
Brindle, K.M.8
Kell, D.B.9
Rowland, J.J.10
Westerhoff, H.V.11
van Dam, K.12
Oliver, S.G.13
-
13
-
-
0034672533
-
The biochemical profile or rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy
-
Griffin. J. L., Troke, J., Walker, L. A., Shore, R. F., Lindon, J. C. and Nicholson, J. K.: The biochemical profile or rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy. FEBS Lett. 2000, 486, 225-229.
-
(2000)
FEBS Lett
, vol.486
, pp. 225-229
-
-
Griffin, J.L.1
Troke, J.2
Walker, L.A.3
Shore, R.F.4
Lindon, J.C.5
Nicholson, J.K.6
-
14
-
-
0033743932
-
NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat
-
Griffin, J. L.,Walker, L. A., Garrod, S., Holmes, E., Shore, R. F., Nicholson, J. K.: NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat. Comp. Biochem. Physiol., B 2000, 127, 357-367.
-
(2000)
Comp. Biochem. Physiol.
, vol.127
, pp. 357-367
-
-
Griffin, J.L.1
Walker, L.A.2
Garrod, S.3
Holmes, E.4
Shore, R.F.5
Nicholson, J.K.6
-
15
-
-
0036707692
-
Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): Identification of new endogenous biomarkers
-
Bundy, J. G., Lenz, E. M., Bailey, N. J., Gavaghan, C. L., Svendsen, C., Spurgeon, D., Hankard, P. K., Osborn, D., Weeks, J. A. and Trauger, S. A.: Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): identification of new endogenous biomarkers. Environ. Toxicol. Chem. 2002, 21, 1966-1972.
-
(2002)
Environ. Toxicol. Chem
, vol.21
, pp. 1966-1972
-
-
Bundy, J.G.1
Lenz, E.M.2
Bailey, N.J.3
Gavaghan, C.L.4
Svendsen, C.5
Spurgeon, D.6
Hankard, P.K.7
Osborn, D.8
Weeks, J.A.9
Trauger, S.A.10
-
16
-
-
0017764472
-
Human erythrocyte metabolism studied by 1H spin echo NMR
-
Brown, F. F., Campbell, I. D., Kuchel, P. W. and Rabenstien, D. L.: Human erythrocyte metabolism studied by 1H spin echo NMR. FEBS Lett. 1977, 82, 12-16.
-
(1977)
FEBS Lett
, vol.82
, pp. 12-16
-
-
Brown, F.F.1
Campbell, I.D.2
Kuchel, P.W.3
Rabenstien, D.L.4
-
17
-
-
65949104353
-
NMR spectroscopy of biofluids
-
Lindon, J. C., Nicholson, J. K. and Everett, J. R.: NMR spectroscopy of biofluids. Annu. Rep. NMR Spectrosc. 1999, 38, 1-88.
-
(1999)
Annu. Rep. NMR Spectrosc.
, vol.38
, pp. 1-88
-
-
Lindon, J.C.1
Nicholson, J.K.2
Everett, J.R.3
-
18
-
-
0021321993
-
Proton-nuclear-magneticresonance studies of serum, plasma and urine from fasting and normal diabetic subjects
-
Nicholson, J. K., O'Flynn, M. P., Sadler, P. J., Macleod, A. F., Juul, S. M. and Sonksen, P. H.: Proton-nuclear-magneticresonance studies of serum, plasma and urine from fasting and normal diabetic subjects. Biochem. J. 1984, 217, 365-375.
-
(1984)
Biochem. J
, vol.217
, pp. 365-375
-
-
Nicholson, J.K.1
O'Flynn, M.P.2
Sadler, P.J.3
Macleod, A.F.4
Juul, S.M.5
Sonksen, P.H.6
-
19
-
-
0021403120
-
Use of high resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine
-
Bales, J. R., Hingham, D. P., Howe, I., Nicholson, J. K. and Sadler, P. J.: Use of high resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine. Clin. Chem. 1984, 30, 426-432.
-
(1984)
Clin. Chem.
, vol.30
, pp. 426-432
-
-
Bales, J.R.1
Hingham, D.P.2
Howe, I.3
Nicholson, J.K.4
Sadler, P.J.5
-
22
-
-
0001413420
-
Metabolite profiling by oneand two-dimensional NMR analysis of complex mixtures Prog
-
Fan, W. M.T.: Metabolite profiling by oneand two-dimensional NMR analysis of complex mixtures Prog. Nucl. Magn. Reson. Spectrosc. 1996. 28, 161-219.
-
(1996)
Nucl. Magn. Reson. Spectrosc
, vol.28
, pp. 161-219
-
-
Fan, W.M.T.1
-
24
-
-
0038012572
-
LC-NMR-MS in drug discovery
-
Corcoran, O. and Spraul, M.: LC-NMR-MS in drug discovery. Drug Disc. Today 2003, 8, 624-631.
-
(2003)
Drug Disc. Today
, vol.8
, pp. 624-631
-
-
Corcoran, O.1
Spraul, M.2
-
25
-
-
0000160422
-
Flow injection nuclear magnetic resonance spectroscopy combined with pattern recognition methods: Implications for rapid structural studies and high throughput biochemical screening
-
Spraul, M., Hofmann, M., Ackermann, M., Nicholls, A. W., Damment, S. J. P., Hasleden, J. N., Shockcor, J. P., Nicholson, J. K. and Lindon, J. C.: Flow injection nuclear magnetic resonance spectroscopy combined with pattern recognition methods: implications for rapid structural studies and high throughput biochemical screening. Anal. Commun. 1997, 34, 339-341.
-
(1997)
Anal. Commun.
, vol.34
, pp. 339-341
-
-
Spraul, M.1
Hofmann, M.2
Ackermann, M.3
Nicholls, A.W.4
Damment, S.J.P.5
Hasleden, J.N.6
Shockcor, J.P.7
Nicholson, J.K.8
Lindon, J.C.9
-
26
-
-
0000973723
-
Magic angle spinning proton nuclear magnetic resonance spectroscopic analysis of intact kidney tissue samples
-
Moka, D.,Vorreuther, R., Schicha, H., Spraul, M., Humpfer, E., Lipinski, M., Foxall, P. J. D., Nicholson, J. K. and Lindon, J. C.: Magic angle spinning proton nuclear magnetic resonance spectroscopic analysis of intact kidney tissue samples. Anal. Commun. 1997, 34, 107-109.
-
(1997)
Anal. Commun.
, vol.34
, pp. 107-109
-
-
Moka, D.1
Vorreuther, R.2
Schicha, H.3
Spraul, M.4
Humpfer, E.5
Lipinski, M.6
Foxall, P.J.D.7
Nicholson, J.K.8
Lindon, J.C.9
-
27
-
-
0036639485
-
NMR and pattern recognition studies on liver extracts and intact livers from rats treated with a-napthylisothiocyanate
-
Waters, N. J., Holmes, E., Waterfield, C. J., Farrant, R. D. and Nicholson, J. K.: NMR and pattern recognition studies on liver extracts and intact livers from rats treated with a-napthylisothiocyanate. Biochem. Pharmacol. 2002, 64, 67-77.
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 67-77
-
-
Waters, N.J.1
Holmes, E.2
Waterfield, C.J.3
Farrant, R.D.4
Nicholson, J.K.5
-
28
-
-
0001560352
-
High resolution magic angle spinning 1H nuclear magnetic resonance analysis of intact prostatic hyperplasic and tumor tissues
-
Tomlins, A. M., Foxall. P. J. D., Lindon, J. C., Lynch, M. J., Spraul, M., Everett, J. R. and Nicholson, J. K.: High resolution magic angle spinning 1H nuclear magnetic resonance analysis of intact prostatic hyperplasic and tumor tissues. Anal. Commun. 1998, 35, 113-115.
-
(1998)
Anal. Commun.
, vol.35
, pp. 113-115
-
-
Tomlins, A.M.1
Foxall, P.J.D.2
Lindon, J.C.3
Lynch, M.J.4
Spraul, M.5
Everett, J.R.6
Nicholson, J.K.7
-
29
-
-
0027288514
-
NMR spectroscopy as a novel approach to the monitoring of renal transplant function
-
Foxall, P. J. D., Mellotte, G. J., Bending, M. R., Lindon, J. C. and Nicholson, J. K.: NMR spectroscopy as a novel approach to the monitoring of renal transplant function. Kidney Int. 1993, 43, 234-245.
-
(1993)
Kidney Int
, vol.43
, pp. 234-245
-
-
Foxall, P.J.D.1
Mellotte, G.J.2
Bending, M.R.3
Lindon, J.C.4
Nicholson, J.K.5
-
30
-
-
0022189601
-
Use of proton nuclear magnetic resonance spectroscopy in detection and study of organic acidurias
-
Iles, R., Hind. A. J. and Chalmers, R. A.: Use of proton nuclear magnetic resonance spectroscopy in detection and study of organic acidurias. Clin. Chem. 1985, 31, 1795-1801.
-
(1985)
Clin. Chem.
, vol.31
, pp. 1795-1801
-
-
Iles, R.1
Hind, A.J.2
Chalmers, R.A.3
-
31
-
-
0003742535
-
Handbook of 1H-NMR spectroscopy in inborn errors of metabolism. Heilbronn: SPS publications
-
Moolenaar, S. H., Engelke, U. F. H., Hoenderop, S. M. G. C., Sewell, A. C., Wagner, L. and Wevers, R. A.: Handbook of 1H-NMR spectroscopy in inborn errors of metabolism. Heilbronn: SPS publications, 2002.
-
(2002)
-
-
Moolenaar, S.H.1
Engelke, U.F.H.2
Hoenderop, S.M.G.C.3
Sewell, A.C.4
Wagner, L.5
Wevers, R.A.6
-
32
-
-
0022470534
-
Possibilities of selective screening for inborn errors of metabolism using high-resolution 1H-FT-NMR spectrometry
-
Lehnert,W. and Hunkler, D.: Possibilities of selective screening for inborn errors of metabolism using high-resolution 1H-FT-NMR spectrometry. Eur. J. Pediatr. 1986, 145, 260-266.
-
(1986)
Eur. J. Pediatr.
, vol.145
, pp. 260-266
-
-
Lehnert, W.1
Hunkler, D.2
-
33
-
-
0034740588
-
HPLC/1H NMR spectroscopic studies of reactive a-1-O-acyl isomer formed during acyl migration of S-naproxen b-1-O-acyl glucuronide
-
Corcoran, O., Mortensen, R. W., Hansen, S. H., Troke, J., and Nicholson, J. K.: HPLC/1H NMR spectroscopic studies of reactive a-1-O-acyl isomer formed during acyl migration of S-naproxen b-1-O-acyl glucuronide. Chem. Res. Toxicol. 2001. 14, 1363-1370.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 1363-1370
-
-
Corcoran, O.1
Mortensen, R.W.2
Hansen, S.H.3
Troke, J.4
Nicholson, J.K.5
-
34
-
-
18744396052
-
Analytical reproducibility in 1H NMR-based metabonomic urinalysis
-
Keun, H. C., Ebbels,T. M. D., Antti, H., Bollard, M. E., Beckonert, O., Schlotterbeck, G., Senn, H., Niederhauser, U., Holmes, E., Lindon, J. C. and Nicholson, J. K.: Analytical reproducibility in 1H NMR-based metabonomic urinalysis. Chem. Res. Toxicol. 2002, 15, 1380-1386.
-
(2002)
Chem. Res. Toxicol.
, vol.15
, pp. 1380-1386
-
-
Keun, H.C.1
Ebbels, T.M.D.2
Antti, H.3
Bollard, M.E.4
Beckonert, O.5
Schlotterbeck, G.6
Senn, H.7
Niederhauser, U.8
Holmes, E.9
Lindon, J.C.10
Nicholson, J.K.11
-
35
-
-
0032456846
-
Biomarkers in toxicology
-
Timbrell, J. A.: Biomarkers in toxicology. Toxicology, 1998, 129, 1-12.
-
(1998)
Toxicology
, vol.129
, pp. 1-12
-
-
Timbrell, J.A.1
-
36
-
-
0024003331
-
Salicylate poisoning detected by 1H NMR spectroscopy
-
Vermeersch, G., Marko, J., Cartigny, B., Leclerc, F., Roussell, P. and Lhermitte, M.: Salicylate poisoning detected by 1H NMR spectroscopy. Clin. Chem. 1988, 34, 1003.
-
(1988)
Clin. Chem.
, vol.34
, pp. 1003
-
-
Vermeersch, G.1
Marko, J.2
Cartigny, B.3
Leclerc, F.4
Roussell, P.5
Lhermitte, M.6
-
37
-
-
0022296430
-
Two-dimensional proton nuclear magnetic resonance "maps" of acetaminophen metabolites in human urine
-
Bales, J. R., Nicholson, J. K. and Sadler, P. J.: Two-dimensional proton nuclear magnetic resonance "maps" of acetaminophen metabolites in human urine. Clin. Chem. 1985, 31, 757.
-
(1985)
Clin. Chem.
, vol.31
, pp. 757
-
-
Bales, J.R.1
Nicholson, J.K.2
Sadler, P.J.3
-
38
-
-
0034743939
-
H NMR spectroscopy investigation of serum and urine in a case of acute tetrahydrofuran poisoning
-
Cartigny, B., Azaroual, N., Imbenotte, M., Sadeg, N., Testart, F., Richecoeur, J.,Vermeersch, G. and Lhermitte, M.: 1H NMR spectroscopy investigation of serum and urine in a case of acute tetrahydrofuran poisoning. J. Anal. Toxicol. 2001, 25, 270-274.
-
(2001)
J. Anal. Toxicol.
, vol.25
, pp. 270-274
-
-
Cartigny, B.1
Azaroual, N.2
Imbenotte, M.3
Sadeg, N.4
Testart, F.5
Richecoeur, J.6
Vermeersch, G.7
Lhermitte, M.8
-
39
-
-
0032589579
-
Determination by 1H NMR spectroscopy of paraquat in urine from acutely poisoned patients: Comparison with second-derivative spectroscopy method
-
Imbenotte, M., Azaroual, N., Mathieu, D., Cartigny, B.,Vermeersch, G. and Lhermitte, M.: Determination by 1H NMR spectroscopy of paraquat in urine from acutely poisoned patients: comparison with second-derivative spectroscopy method. J. Anal. Toxicol. 1999, 23, 586-590.
-
(1999)
J. Anal. Toxicol.
, vol.23
, pp. 586-590
-
-
Imbenotte, M.1
Azaroual, N.2
Mathieu, D.3
Cartigny, B.4
Vermeersch, G.5
Lhermitte, M.6
-
40
-
-
0023161935
-
H NMR of human saliva: An application of NMR spectroscopy in forensic science
-
Harada, H., Shimizu, H. and Maeiwa, M.: 1H NMR of human saliva: an application of NMR spectroscopy in forensic science. Forensic Sci. Int. 1987, 34, 189-195.
-
(1987)
Forensic Sci. Int.
, vol.34
, pp. 189-195
-
-
Harada, H.1
Shimizu, H.2
Maeiwa, M.3
-
41
-
-
0036707910
-
1H NMR urine analysis as an effective tool to detect creatine supplementation
-
Cartigny, B., Azaroual, N., MilleHamard, L., Imbenotte, M., Kintz, P., Vermeersch, G. and Lhermitte, M.: 1H NMR urine analysis as an effective tool to detect creatine supplementation. J. Anal. Toxicol. 2002, 26, 355-359.
-
(2002)
J. Anal. Toxicol.
, vol.26
, pp. 355-359
-
-
Cartigny, B.1
Azaroual, N.2
MilleHamard, L.3
Imbenotte, M.4
Kintz, P.5
Vermeersch, G.6
Lhermitte, M.7
-
42
-
-
84956827552
-
Application of genomics, proteomics, and metabonomics technologies to the development of medical countermeasures against chemical warfare agents
-
Dec 2-5
-
Schlager, J. J., Sabourin, C. L. K., Johnston, D. S., Midboe, E. G. and Dillman, J. F.: Application of genomics, proteomics, and metabonomics technologies to the development of medical countermeasures against chemical warfare agents. Army Science Conference, Dec 2-5, 2002, http://www.asc2002.com/summaries/d/ DP-04.pdf.
-
(2002)
Army Science Conference
-
-
Schlager, J.J.1
Sabourin, C.L.K.2
Johnston, D.S.3
Midboe, E.G.4
Dillman, J.F.5
-
43
-
-
0001501332
-
Spectroscopic investigations of tissue metabolite biomarker response to Cu(II) exposure in terrestrial invertebrates: Identification of free histidine as a novel biomarker of exposure to copper in earthworms
-
Gibb, J. O. T., Svendsen, C.,Weeks, J. M. and Nicholson, J. K.: Spectroscopic investigations of tissue metabolite biomarker response to Cu(II) exposure in terrestrial invertebrates: identification of free histidine as a novel biomarker of exposure to copper in earthworms. Biomarkers, 1997, 2, 295-302.
-
(1997)
Biomarkers
, vol.2
, pp. 295-302
-
-
Gibb, J.O.T.1
Svendsen, C.2
Weeks, J.M.3
Nicholson, J.K.4
-
44
-
-
0035968112
-
An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress
-
Bundy, J. G., Osborn, D., Weeks, J. M., Lindon, J. C and Nicholson, J. K.: An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress. FEBS Lett. 2001, 500, 31-35.
-
(2001)
FEBS Lett.
, vol.500
, pp. 31-35
-
-
Bundy, J.G.1
Osborn, D.2
Weeks, J.M.3
Lindon, J.C.4
Nicholson, J.K.5
-
45
-
-
0345270396
-
Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics
-
Bailey, N. J. C., Oven, M., Holmes, E., Nicholson, J. K. and Zenk, M. H.: Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics. Phytochemistry 2003, 62, 851-858.
-
(2003)
Phytochemistry
, vol.62
, pp. 851-858
-
-
Bailey, N.J.C.1
Oven, M.2
Holmes, E.3
Nicholson, J.K.4
Zenk, M.H.5
-
46
-
-
0000806615
-
Rapid multi-component detection of fluorinated drug metabolites in whole urine from a 'cassette' dose study using high resolution 19F NMR spectroscopy
-
Corcoran, O., Wilson, I. D. and Nicholson, J. K.: Rapid multi-component detection of fluorinated drug metabolites in whole urine from a 'cassette' dose study using high resolution 19F NMR spectroscopy. Anal. Commun. 1999, 36, 259-261.
-
(1999)
Anal. Commun.
, vol.36
, pp. 259-261
-
-
Corcoran, O.1
Wilson, I.D.2
Nicholson, J.K.3
-
47
-
-
0035543764
-
The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism
-
Corcoran, O., Lindon, J. C., Hall, R., Ismail, I. M. and Nicholson, J. K.: The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism. Analyst, 2001, 126, 2103-2106.
-
(2001)
Analyst
, vol.126
, pp. 2103-2106
-
-
Corcoran, O.1
Lindon, J.C.2
Hall, R.3
Ismail, I.M.4
Nicholson, J.K.5
-
48
-
-
0036707428
-
Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies
-
Keun, H. C., Beckonert, O., Griffin, J. L., Richter, C., Moskau, D., Lindon, J. C. and Nicholson, J. K.: Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies. Anal. Chem. 2002, 74, 4588-4593.
-
(2002)
Anal. Chem.
, vol.74
, pp. 4588-4593
-
-
Keun, H.C.1
Beckonert, O.2
Griffin, J.L.3
Richter, C.4
Moskau, D.5
Lindon, J.C.6
Nicholson, J.K.7
-
49
-
-
0037444518
-
Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: Application to the analysis of acetaminophen metabolites in urine
-
Spraul, M., Freund, A. S., Nast, R. E., Withers, R. S., Maas, W. E. and Corcoran, O.: Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: application to the analysis of acetaminophen metabolites in urine. Anal. Chem. 2003, 75, 1536-1541.
-
(2003)
Anal. Chem.
, vol.75
, pp. 1536-1541
-
-
Spraul, M.1
Freund, A.S.2
Nast, R.E.3
Withers, R.S.4
Maas, W.E.5
Corcoran, O.6
-
50
-
-
0036586458
-
Advancing sensitivity for flow NMR spectroscopy: LC-SPE-NMR and capillary scale LC-NMR
-
Corcoran, O., Wilkinson, P. S., Godejohann, M., Braumann, U., Hofmann, M. and Spraul, M.: Advancing sensitivity for flow NMR spectroscopy: LC-SPE-NMR and capillary scale LC-NMR. Am. Lab. Chrom. Perspectives, 2002, 34, 18-21.
-
(2002)
Am. Lab. Chrom. Perspectives
, vol.34
, pp. 18-21
-
-
Corcoran, O.1
Wilkinson, P.S.2
Godejohann, M.3
Braumann, U.4
Hofmann, M.5
Spraul, M.6
-
51
-
-
84956827151
-
-
Bruker BioSpin, INCA system, www.bruker-biospin.com/nmr/ http://www.bruker-biospin.com/nmr/ products/av_inca.html
-
INCA system
-
-
Bruker, B.1
-
52
-
-
0035369191
-
Metabolic profiling of genetic disorders: A multitissue 1H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue
-
Griffin, J. L., Williams, H. J., Sang, E., Clarke, K., Rae, C. and Nicholson, J. K.: Metabolic profiling of genetic disorders: a multitissue 1H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue. Anal. Biochem. 2001, 293, 16-21.
-
(2001)
Anal. Biochem.
, vol.293
, pp. 16-21
-
-
Griffin, J.L.1
Williams, H.J.2
Sang, E.3
Clarke, K.4
Rae, C.5
Nicholson, J.K.6
-
53
-
-
84956768511
-
-
Biological Atlas of Insulin Resistance Project
-
Biological Atlas of Insulin Resistance Project, www.bair.org.uk. http://www.bair.org.uk/
-
-
-
|