메뉴 건너뛰기




Volumn 32, Issue 8, 2007, Pages 1791-1804

Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics

Author keywords

Cytokine; Dopamine; LPS; Neurodevelopment; Prepulse inhibition; Schizophrenia

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; HALOPERIDOL; LIPOPOLYSACCHARIDE; NEUROLEPTIC AGENT; NEUROMODULIN; PHOSPHOPROTEIN DARPP 32; SYNAPTOPHYSIN;

EID: 34447530505     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301292     Document Type: Article
Times cited : (112)

References (91)
  • 2
    • 0028800496 scopus 로고
    • Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses
    • Alder J, Kanki H, Valtorta F, Greengard P, Poo MM (1995). Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses. J Neurosci 15: 511-519.
    • (1995) J Neurosci , vol.15 , pp. 511-519
    • Alder, J.1    Kanki, H.2    Valtorta, F.3    Greengard, P.4    Poo, M.M.5
  • 3
    • 0024439539 scopus 로고
    • Localization of interleukin-2 immunoreactivity and interleukin-2 receptors in the rat brain: Interaction with the cholinergic system
    • Araujo DM, Lapchak PA, Collier B, Quirion R (1989). Localization of interleukin-2 immunoreactivity and interleukin-2 receptors in the rat brain: interaction with the cholinergic system. Brain Res 498: 257-266.
    • (1989) Brain Res , vol.498 , pp. 257-266
    • Araujo, D.M.1    Lapchak, P.A.2    Collier, B.3    Quirion, R.4
  • 4
    • 32844463928 scopus 로고    scopus 로고
    • The role of cytokines in mediating effects of prenatal infection on the fetus: Implications for schizophrenia
    • Ashdown H, Dumont Y, Ng M, Poole S, Boksa P, Luheshi GN (2006). The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia. Mol Psychiatry 11: 47-55.
    • (2006) Mol Psychiatry , vol.11 , pp. 47-55
    • Ashdown, H.1    Dumont, Y.2    Ng, M.3    Poole, S.4    Boksa, P.5    Luheshi, G.N.6
  • 6
    • 0028049995 scopus 로고
    • Penetration of interleukin-6 across the murine blood-brain barrier
    • Banks WA, Kastin AJ, Gutierrez EG (1994). Penetration of interleukin-6 across the murine blood-brain barrier. Neurosci Lett 179: 53-56.
    • (1994) Neurosci Lett , vol.179 , pp. 53-56
    • Banks, W.A.1    Kastin, A.J.2    Gutierrez, E.G.3
  • 7
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43: An intrinsic determinant of neuronal development and plasticity
    • Benowitz LI, Routtenberg A (1997). GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci 20: 84-91.
    • (1997) Trends Neurosci , vol.20 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 8
    • 2542524716 scopus 로고    scopus 로고
    • Long-term alterations in neuroimmune responses after neonatal exposure to lipopolysaccharide
    • Boisse L, Mouihate A, Ellis S, Pittman QJ (2004). Long-term alterations in neuroimmune responses after neonatal exposure to lipopolysaccharide. J Neurosci 24: 4928-4934.
    • (2004) J Neurosci , vol.24 , pp. 4928-4934
    • Boisse, L.1    Mouihate, A.2    Ellis, S.3    Pittman, Q.J.4
  • 9
    • 0036150201 scopus 로고    scopus 로고
    • Prenatal immune challenge disrupts sensorimotor gating in adult rats. Implications for the etiopathogenesis of schizophrenia
    • Borrell J, Vela JM, Arevalo-Martin A, Molina-Holgado E, Guaza C (2002). Prenatal immune challenge disrupts sensorimotor gating in adult rats. Implications for the etiopathogenesis of schizophrenia. Neuropsychopharmacology 26: 204-215.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 204-215
    • Borrell, J.1    Vela, J.M.2    Arevalo-Martin, A.3    Molina-Holgado, E.4    Guaza, C.5
  • 10
  • 11
    • 33645217100 scopus 로고    scopus 로고
    • Prenatal infection as a risk factor for schizophrenia
    • Brown AS (2006). Prenatal infection as a risk factor for schizophrenia. Schizophr Bull 32: 200-202.
    • (2006) Schizophr Bull , vol.32 , pp. 200-202
    • Brown, A.S.1
  • 13
    • 2442593823 scopus 로고    scopus 로고
    • Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring
    • Brown AS, Hooton J, Schaefer CA, Zhang H, Petkova E, Babulas V et al (2004b). Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry 161: 889-895.
    • (2004) Am J Psychiatry , vol.161 , pp. 889-895
    • Brown, A.S.1    Hooton, J.2    Schaefer, C.A.3    Zhang, H.4    Petkova, E.5    Babulas, V.6
  • 16
    • 0028842153 scopus 로고
    • Prepulse inhibition of the acoustic startle reflex using visual and auditory prepulses: Disruption by apomorphine
    • Campeau S, Davis M (1995). Prepulse inhibition of the acoustic startle reflex using visual and auditory prepulses: disruption by apomorphine. Psychopharmacology (Berlin) 117: 267-274.
    • (1995) Psychopharmacology (Berlin) , vol.117 , pp. 267-274
    • Campeau, S.1    Davis, M.2
  • 18
    • 0026611392 scopus 로고
    • The regulation of subcortical dopamine systems by the prefrontal cortex: Interactions of central dopamine systems and the pathogenesis of schizophrenia
    • Deutch AY (1992). The regulation of subcortical dopamine systems by the prefrontal cortex: interactions of central dopamine systems and the pathogenesis of schizophrenia. J Neural Transm Suppl 36: 61-89.
    • (1992) J Neural Transm Suppl , vol.36 , pp. 61-89
    • Deutch, A.Y.1
  • 20
    • 2342656384 scopus 로고    scopus 로고
    • The synaptic pathology of schizophrenia: Is aberrant neurodevelopment and plasticity to blame?
    • Eastwood SL (2004). The synaptic pathology of schizophrenia: is aberrant neurodevelopment and plasticity to blame? Int Rev Neurobiol 59: 47-72.
    • (2004) Int Rev Neurobiol , vol.59 , pp. 47-72
    • Eastwood, S.L.1
  • 21
    • 0032502849 scopus 로고    scopus 로고
    • The effects of an early stressful life event on sensorimotor gating in adult rats
    • Ellenbroek BA, van den Kroonenberg PT, Cools AR (1998). The effects of an early stressful life event on sensorimotor gating in adult rats. Schizophr Res 30: 251-260.
    • (1998) Schizophr Res , vol.30 , pp. 251-260
    • Ellenbroek, B.A.1    van den Kroonenberg, P.T.2    Cools, A.R.3
  • 22
    • 28844501953 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of synaptophysin in synaptic vesicle recycling
    • Evans GJ, Cousin MA (2005). Tyrosine phosphorylation of synaptophysin in synaptic vesicle recycling. Biochem Soc Trans 33: 1350-1353.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1350-1353
    • Evans, G.J.1    Cousin, M.A.2
  • 23
    • 0032572605 scopus 로고    scopus 로고
    • Differential expression of synaptosome-associated protein 25 kDa [SNAP-25] in hippocampi of neonatal mice following exposure to human influenza virus in utero
    • Fatemi SH, Sidwell R, Kist D, Akhter P, Meltzer HY, Bailey K et al (1998). Differential expression of synaptosome-associated protein 25 kDa [SNAP-25] in hippocampi of neonatal mice following exposure to human influenza virus in utero. Brain Res 800: 1-9.
    • (1998) Brain Res , vol.800 , pp. 1-9
    • Fatemi, S.H.1    Sidwell, R.2    Kist, D.3    Akhter, P.4    Meltzer, H.Y.5    Bailey, K.6
  • 25
    • 1542315608 scopus 로고    scopus 로고
    • Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring
    • Fortier ME, Joober R, Luheshi GN, Boksa P (2004). Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring. J Psychiatr Res 38: 335-345.
    • (2004) J Psychiatr Res , vol.38 , pp. 335-345
    • Fortier, M.E.1    Joober, R.2    Luheshi, G.N.3    Boksa, P.4
  • 26
    • 0028069262 scopus 로고
    • Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development
    • Gadient RA, Otten U (1994). Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development. Brain Res 637: 10-14.
    • (1994) Brain Res , vol.637 , pp. 10-14
    • Gadient, R.A.1    Otten, U.2
  • 28
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: A decade in review
    • Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001). Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berlin) 156: 117-154.
    • (2001) Psychopharmacology (Berlin) , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Thomson, K.2    Braff, D.L.3    Swerdlow, N.R.4
  • 29
    • 2942683385 scopus 로고    scopus 로고
    • Prenatal infection and risk for schizophrenia: IL-1beta, IL-6, and TNFalpha inhibit cortical neuron dendrite development
    • Gilmore JH, Fredrik JL, Vadlamudi S, Lauder JM (2004). Prenatal infection and risk for schizophrenia: IL-1beta, IL-6, and TNFalpha inhibit cortical neuron dendrite development. Neuropsychopharmacology 29: 1221-1229.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1221-1229
    • Gilmore, J.H.1    Fredrik, J.L.2    Vadlamudi, S.3    Lauder, J.M.4
  • 30
    • 0038297673 scopus 로고    scopus 로고
    • Maternal infection regulates BDNF and NGF expression in fetal and neonatal brain and maternal-fetal unit of the rat
    • Gilmore JH, Jarskog LF, Vadlamudi S (2003). Maternal infection regulates BDNF and NGF expression in fetal and neonatal brain and maternal-fetal unit of the rat. J Neuroimmunol 138: 49-55.
    • (2003) J Neuroimmunol , vol.138 , pp. 49-55
    • Gilmore, J.H.1    Jarskog, L.F.2    Vadlamudi, S.3
  • 31
    • 12344280393 scopus 로고    scopus 로고
    • Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat
    • Gilmore JH, Jarskog LF, Vadlamudi S (2005). Maternal poly I:C exposure during pregnancy regulates TNF alpha, BDNF, and NGF expression in neonatal brain and the maternal-fetal unit of the rat. J Neuroimmunol 159: 106-112.
    • (2005) J Neuroimmunol , vol.159 , pp. 106-112
    • Gilmore, J.H.1    Jarskog, L.F.2    Vadlamudi, S.3
  • 32
    • 2542587762 scopus 로고    scopus 로고
    • Distinct expression and distribution of vesicular proteins in the hippocampus of TNFa-deficient mice during development
    • Golan H, Levav T, Huleihel M (2004). Distinct expression and distribution of vesicular proteins in the hippocampus of TNFa-deficient mice during development. Synapse 53: 6-10.
    • (2004) Synapse , vol.53 , pp. 6-10
    • Golan, H.1    Levav, T.2    Huleihel, M.3
  • 33
    • 16844384338 scopus 로고    scopus 로고
    • Specific neurodevelopmental damage in mice offspring following maternal inflammation during pregnancy
    • Golan HM, Lev V, Hallak M, Sorokin Y, Huleihel M (2005). Specific neurodevelopmental damage in mice offspring following maternal inflammation during pregnancy. Neuropharmacology 48: 903-917.
    • (2005) Neuropharmacology , vol.48 , pp. 903-917
    • Golan, H.M.1    Lev, V.2    Hallak, M.3    Sorokin, Y.4    Huleihel, M.5
  • 34
    • 0016504948 scopus 로고
    • Presidential address, 1974. The more or less startling effects of weak prestimulation
    • Graham FK (1975). Presidential address, 1974. The more or less startling effects of weak prestimulation. Psychophysiology 12: 238-248.
    • (1975) Psychophysiology , vol.12 , pp. 238-248
    • Graham, F.K.1
  • 35
    • 0027517309 scopus 로고
    • Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
    • Gutierrez EG, Banks WA, Kastin AJ (1993). Murine tumor necrosis factor alpha is transported from blood to brain in the mouse. J Neuroimmunol 47: 169-176.
    • (1993) J Neuroimmunol , vol.47 , pp. 169-176
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 36
    • 0042831054 scopus 로고    scopus 로고
    • Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development
    • Halim ND, Weickert CS, McClintock BW, Hyde TM, Weinberger DR, Kleinman JE et al (2003). Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development. Mol Psychiatry 8: 797-810.
    • (2003) Mol Psychiatry , vol.8 , pp. 797-810
    • Halim, N.D.1    Weickert, C.S.2    McClintock, B.W.3    Hyde, T.M.4    Weinberger, D.R.5    Kleinman, J.E.6
  • 37
    • 0031941351 scopus 로고    scopus 로고
    • Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients
    • Hazlett EA, Buchsbaum MS, Haznedar MM, Singer MB, Germans MK, Schnur DB et al (1998). Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients. Psychophysiology 35: 186-198.
    • (1998) Psychophysiology , vol.35 , pp. 186-198
    • Hazlett, E.A.1    Buchsbaum, M.S.2    Haznedar, M.M.3    Singer, M.B.4    Germans, M.K.5    Schnur, D.B.6
  • 38
    • 0035200091 scopus 로고    scopus 로고
    • Neonatal endotoxin exposure influences HPA responsivity and impairs tumor immunity in Fischer 344 rats in adulthood
    • Hodgson DM, Knott B, Walker FR (2001). Neonatal endotoxin exposure influences HPA responsivity and impairs tumor immunity in Fischer 344 rats in adulthood. Pediatr Res 50: 750-755.
    • (2001) Pediatr Res , vol.50 , pp. 750-755
    • Hodgson, D.M.1    Knott, B.2    Walker, F.R.3
  • 39
    • 0033091035 scopus 로고    scopus 로고
    • Assessing the machinery of mind: Synapses in neuropsychiatric disorders
    • Honer WG (1999). Assessing the machinery of mind: synapses in neuropsychiatric disorders. J Psychiatry Neurosci 24: 116-121.
    • (1999) J Psychiatry Neurosci , vol.24 , pp. 116-121
    • Honer, W.G.1
  • 41
    • 0029920893 scopus 로고    scopus 로고
    • Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat
    • Humby T, Wilkinson LS, Robbins TW, Geyer MA (1996). Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat. J Neurosci 16: 2149-2156.
    • (1996) J Neurosci , vol.16 , pp. 2149-2156
    • Humby, T.1    Wilkinson, L.S.2    Robbins, T.W.3    Geyer, M.A.4
  • 42
    • 0034534059 scopus 로고    scopus 로고
    • Cytokine responses to LTP induction in the rat hippocampus: A comparison of in vitro and in vivo techniques
    • Jankowsky JL, Derrick BE, Patterson PH (2000). Cytokine responses to LTP induction in the rat hippocampus: a comparison of in vitro and in vivo techniques. Learn Mem 7: 400-412.
    • (2000) Learn Mem , vol.7 , pp. 400-412
    • Jankowsky, J.L.1    Derrick, B.E.2    Patterson, P.H.3
  • 43
    • 0031581047 scopus 로고    scopus 로고
    • Cytokine regulation of embryonic rat dopamine and serotonin neuronal survival in vitro
    • Jarskog LF, Xiao H, Wilkie MB, Lauder JM, Gilmore JH (1997). Cytokine regulation of embryonic rat dopamine and serotonin neuronal survival in vitro. Int J Dev Neurosci 15: 711-716.
    • (1997) Int J Dev Neurosci , vol.15 , pp. 711-716
    • Jarskog, L.F.1    Xiao, H.2    Wilkie, M.B.3    Lauder, J.M.4    Gilmore, J.H.5
  • 44
    • 0033006832 scopus 로고    scopus 로고
    • Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: A possible neurochemical basis for 'hypofrontality'
    • Karson CN, Mrak RE, Schluterman KO, Sturner WQ, Sheng JG, Griffin WS (1999). Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: a possible neurochemical basis for 'hypofrontality'. Mol Psychiatry 4: 39-45.
    • (1999) Mol Psychiatry , vol.4 , pp. 39-45
    • Karson, C.N.1    Mrak, R.E.2    Schluterman, K.O.3    Sturner, W.Q.4    Sheng, J.G.5    Griffin, W.S.6
  • 46
    • 2342622581 scopus 로고    scopus 로고
    • Antisense knockdown of drebrin A, a dendritic spine protein, causes stronger preference, impaired pre-pulse inhibition, and an increased sensitivity to psychostimulant
    • Kobayashi R, Sekino Y, Shirao T, Tanaka S, Ogura T, Inada K et al (2004). Antisense knockdown of drebrin A, a dendritic spine protein, causes stronger preference, impaired pre-pulse inhibition, and an increased sensitivity to psychostimulant. Neurosci Res 49: 205-217.
    • (2004) Neurosci Res , vol.49 , pp. 205-217
    • Kobayashi, R.1    Sekino, Y.2    Shirao, T.3    Tanaka, S.4    Ogura, T.5    Inada, K.6
  • 47
    • 0035397968 scopus 로고    scopus 로고
    • Neuroleptics normalize increased release of interleukin-1 beta and tumor necrosis factor-alpha from monocytes in schizophrenia
    • Kowalski J, Blada P, Kucia K, Madej A, Herman ZS (2001). Neuroleptics normalize increased release of interleukin-1 beta and tumor necrosis factor-alpha from monocytes in schizophrenia. Schizophr Res 50: 169-175.
    • (2001) Schizophr Res , vol.50 , pp. 169-175
    • Kowalski, J.1    Blada, P.2    Kucia, K.3    Madej, A.4    Herman, Z.S.5
  • 48
    • 0033007525 scopus 로고    scopus 로고
    • Normalization of information processing deficits in schizophrenia with clozapine
    • Kumari V, Soni W, Sharma T (1999). Normalization of information processing deficits in schizophrenia with clozapine. Am J Psychiatry 156: 1046-1051.
    • (1999) Am J Psychiatry , vol.156 , pp. 1046-1051
    • Kumari, V.1    Soni, W.2    Sharma, T.3
  • 49
    • 0036308284 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of neurodevelopment
    • Lewis DA, Levitt P (2002). Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci 25: 409-432.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 409-432
    • Lewis, D.A.1    Levitt, P.2
  • 50
    • 0033638576 scopus 로고    scopus 로고
    • Catching up on schizophrenia: Natural history and neurobiology
    • Lewis DA, Lieberman JA (2000). Catching up on schizophrenia: natural history and neurobiology. Neuron 28: 325-334.
    • (2000) Neuron , vol.28 , pp. 325-334
    • Lewis, D.A.1    Lieberman, J.A.2
  • 51
    • 0027202034 scopus 로고
    • Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients
    • Licinio J, Seibyl JP, Altemus M, Charney DS, Krystal JH (1993). Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients. Am J Psychiatry 150: 1408-1410.
    • (1993) Am J Psychiatry , vol.150 , pp. 1408-1410
    • Licinio, J.1    Seibyl, J.P.2    Altemus, M.3    Charney, D.S.4    Krystal, J.H.5
  • 52
    • 4444316217 scopus 로고    scopus 로고
    • Using animal models to test a neurodevelopmental hypothesis of schizophrenia
    • Lipska BK (2004). Using animal models to test a neurodevelopmental hypothesis of schizophrenia. J Psychiatry Neurosci 29: 282-286.
    • (2004) J Psychiatry Neurosci , vol.29 , pp. 282-286
    • Lipska, B.K.1
  • 53
    • 0029113540 scopus 로고
    • Increases in CSF levels of interleukin-2 in schizophrenia: Effects of recurrence of psychosis and medication status
    • McAllister CG, van Kammen DP, Rehn TJ, Miller AL, Gurklis J, Kelley ME et al (1995). Increases in CSF levels of interleukin-2 in schizophrenia: effects of recurrence of psychosis and medication status. Am J Psychiatry 152: 1291-1297.
    • (1995) Am J Psychiatry , vol.152 , pp. 1291-1297
    • McAllister, C.G.1    van Kammen, D.P.2    Rehn, T.J.3    Miller, A.L.4    Gurklis, J.5    Kelley, M.E.6
  • 54
    • 0023850031 scopus 로고
    • Adult schizophrenia following prenatal exposure to an influenza epidemic
    • Mednick SA, Machon RA, Huttunen MO, Bonett D (1988). Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch Gen Psychiatry 45: 189-192.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 189-192
    • Mednick, S.A.1    Machon, R.A.2    Huttunen, M.O.3    Bonett, D.4
  • 55
    • 33646926705 scopus 로고    scopus 로고
    • The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology
    • Meyer U, Nyffeler M, Engler A, Urwyler A, Schedlowski M, Knuesel I et al (2006). The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. J Neurosci 26: 4752-4762.
    • (2006) J Neurosci , vol.26 , pp. 4752-4762
    • Meyer, U.1    Nyffeler, M.2    Engler, A.3    Urwyler, A.4    Schedlowski, M.5    Knuesel, I.6
  • 56
    • 33745698337 scopus 로고    scopus 로고
    • Critical appraisal of DNA microarrays in psychiatric genomics
    • Mirnics K, Levitt P, Lewis DA (2006). Critical appraisal of DNA microarrays in psychiatric genomics. Biol Psychiatry 60: 163-176.
    • (2006) Biol Psychiatry , vol.60 , pp. 163-176
    • Mirnics, K.1    Levitt, P.2    Lewis, D.A.3
  • 57
    • 0030837349 scopus 로고    scopus 로고
    • Plasma levels of interleukin-6 and tumor necrosis factor alpha in chronic schizophrenia: Effects of clozapine treatment
    • Monteleone P, Fabrazzo M, Tortorella A, Maj M (1997). Plasma levels of interleukin-6 and tumor necrosis factor alpha in chronic schizophrenia: effects of clozapine treatment. Psychiatry Res 71: 11-17.
    • (1997) Psychiatry Res , vol.71 , pp. 11-17
    • Monteleone, P.1    Fabrazzo, M.2    Tortorella, A.3    Maj, M.4
  • 58
    • 33748616003 scopus 로고    scopus 로고
    • Recent progress in animal modeling of immune inflammatory processes in schizophrenia: Implication of specific cytokines
    • Nawa H, Takei N (2006). Recent progress in animal modeling of immune inflammatory processes in schizophrenia: implication of specific cytokines. Neurosci Res 56: 2-13.
    • (2006) Neurosci Res , vol.56 , pp. 2-13
    • Nawa, H.1    Takei, N.2
  • 59
    • 0026713997 scopus 로고
    • Effect of chronic treatment with recombinant interleukin-2 on the central nervous system of adult and old mice
    • Nemni R, Iannaccone S, Quattrini A, Smirne S, Sessa M, Lodi M et al (1992). Effect of chronic treatment with recombinant interleukin-2 on the central nervous system of adult and old mice. Brain Res 591: 248-252.
    • (1992) Brain Res , vol.591 , pp. 248-252
    • Nemni, R.1    Iannaccone, S.2    Quattrini, A.3    Smirne, S.4    Sessa, M.5    Lodi, M.6
  • 62
    • 0029036943 scopus 로고
    • Interleukin 2 suppresses afferent sensory transmission in the primary somatosensory cortex
    • Park HJ, Won CK, Pyun KH, Shin HC (1995). Interleukin 2 suppresses afferent sensory transmission in the primary somatosensory cortex. Neuroreport 6: 1018-1020.
    • (1995) Neuroreport , vol.6 , pp. 1018-1020
    • Park, H.J.1    Won, C.K.2    Pyun, K.H.3    Shin, H.C.4
  • 64
    • 0032891837 scopus 로고    scopus 로고
    • Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat
    • Quan N, Stern EL, Whiteside MB, Herkenham M (1999). Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat. J Neuroimmunol 93: 72-80.
    • (1999) J Neuroimmunol , vol.93 , pp. 72-80
    • Quan, N.1    Stern, E.L.2    Whiteside, M.B.3    Herkenham, M.4
  • 66
    • 33646472435 scopus 로고    scopus 로고
    • Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABA(A) dysregulation and impaired spatial learning
    • Samuelsson AM, Jennische E, Hansson HA, Holmang A (2006). Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABA(A) dysregulation and impaired spatial learning. Am J Physiol Regul Integr Comp Physiol 290: R1345-R1356.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Samuelsson, A.M.1    Jennische, E.2    Hansson, H.A.3    Holmang, A.4
  • 67
    • 0027423232 scopus 로고
    • Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain
    • Schobitz B, de Kloet ER, Sutanto W, Holsboer F (1993). Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain. Eur J Neurosci 5: 1426-1435.
    • (1993) Eur J Neurosci , vol.5 , pp. 1426-1435
    • Schobitz, B.1    de Kloet, E.R.2    Sutanto, W.3    Holsboer, F.4
  • 68
    • 0346023029 scopus 로고    scopus 로고
    • Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats
    • Schwabe K, Koch M (2004). Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats. Neurosci Lett 355: 5-8.
    • (2004) Neurosci Lett , vol.355 , pp. 5-8
    • Schwabe, K.1    Koch, M.2
  • 69
    • 0025279451 scopus 로고    scopus 로고
    • See RE, Ellison G (1990). Comparison of chronic administration of haloperidol and the atypical neuroleptics, clozapine and raclopride, in an animal model of tardive dyskinesia. Eur J Pharmacol 181: 175-186.
    • See RE, Ellison G (1990). Comparison of chronic administration of haloperidol and the atypical neuroleptics, clozapine and raclopride, in an animal model of tardive dyskinesia. Eur J Pharmacol 181: 175-186.
  • 70
    • 0034624999 scopus 로고    scopus 로고
    • Early-life exposure to endotoxin alters hypothalamic-pituitary- adrenal function and predisposition to inflammation
    • Shanks N, Windle RJ, Perks PA, Harbuz MS, Jessop DS, Ingram CD et al (2000). Early-life exposure to endotoxin alters hypothalamic-pituitary- adrenal function and predisposition to inflammation. Proc Natl Acad Sci USA 97: 5645-5650.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5645-5650
    • Shanks, N.1    Windle, R.J.2    Perks, P.A.3    Harbuz, M.S.4    Jessop, D.S.5    Ingram, C.D.6
  • 71
    • 0037218688 scopus 로고    scopus 로고
    • Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
    • Shi L, Fatemi SH, Sidwell RW, Patterson PH (2003). Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci 23: 297-302.
    • (2003) J Neurosci , vol.23 , pp. 297-302
    • Shi, L.1    Fatemi, S.H.2    Sidwell, R.W.3    Patterson, P.H.4
  • 72
    • 0032535013 scopus 로고    scopus 로고
    • A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor
    • Snyder GL, Fienberg AA, Huganir RL, Greengard P (1998). A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor. J Neurosci 18: 10297-10303.
    • (1998) J Neurosci , vol.18 , pp. 10297-10303
    • Snyder, G.L.1    Fienberg, A.A.2    Huganir, R.L.3    Greengard, P.4
  • 73
    • 0033047338 scopus 로고    scopus 로고
    • Association between prenatal exposure to poliovirus infection and adult schizophrenia
    • Suvisaari J, Haukka J, Tanskanen A, Hovi T, Lonnqvist J (1999). Association between prenatal exposure to poliovirus infection and adult schizophrenia. Am J Psychiatry 156: 1100-1102.
    • (1999) Am J Psychiatry , vol.156 , pp. 1100-1102
    • Suvisaari, J.1    Haukka, J.2    Tanskanen, A.3    Hovi, T.4    Lonnqvist, J.5
  • 74
    • 0022470792 scopus 로고
    • Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics
    • Swerdlow NR, Braff DL, Geyer MA, Koob GF (1986). Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics. Biol Psychiatry 21: 23-33.
    • (1986) Biol Psychiatry , vol.21 , pp. 23-33
    • Swerdlow, N.R.1    Braff, D.L.2    Geyer, M.A.3    Koob, G.F.4
  • 75
    • 0031720755 scopus 로고    scopus 로고
    • Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
    • Swerdlow NR, Geyer MA (1998). Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull 24: 285-301.
    • (1998) Schizophr Bull , vol.24 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 76
    • 0023216782 scopus 로고
    • Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: Effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry
    • Swerdlow NR, Koob GF (1987). Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry. Brain Res 412: 233-243.
    • (1987) Brain Res , vol.412 , pp. 233-243
    • Swerdlow, N.R.1    Koob, G.F.2
  • 78
    • 0025061972 scopus 로고
    • Interleukin-2 suppresses established long-term potentiation and inhibits its induction in the rat hippocampus
    • Tancredi V, Zona C, Velotti F, Eusebi F, Santoni A (1990). Interleukin-2 suppresses established long-term potentiation and inhibits its induction in the rat hippocampus. Brain Res 525: 149-151.
    • (1990) Brain Res , vol.525 , pp. 149-151
    • Tancredi, V.1    Zona, C.2    Velotti, F.3    Eusebi, F.4    Santoni, A.5
  • 80
    • 3543121321 scopus 로고    scopus 로고
    • Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: Implication in psychiatric disorders of developmental origin
    • Tohmi M, Tsuda N, Watanabe Y, Kakita A, Nawa H (2004). Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: implication in psychiatric disorders of developmental origin. Neurosci Res 50: 67-75.
    • (2004) Neurosci Res , vol.50 , pp. 67-75
    • Tohmi, M.1    Tsuda, N.2    Watanabe, Y.3    Kakita, A.4    Nawa, H.5
  • 81
    • 0035863166 scopus 로고    scopus 로고
    • Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain
    • Urakubo A, Jarskog LF, Lieberman JA, Gilmore JH (2001). Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain. Schizophr Res 47: 27-36.
    • (2001) Schizophr Res , vol.47 , pp. 27-36
    • Urakubo, A.1    Jarskog, L.F.2    Lieberman, J.A.3    Gilmore, J.H.4
  • 82
    • 0028294042 scopus 로고
    • Interleukin-2 does not cross the blood-brain barrier by a saturable transport system
    • Waguespack PJ, Banks WA, Kastin AJ (1994). Interleukin-2 does not cross the blood-brain barrier by a saturable transport system. Brain Res Bull 34: 103-109.
    • (1994) Brain Res Bull , vol.34 , pp. 103-109
    • Waguespack, P.J.1    Banks, W.A.2    Kastin, A.J.3
  • 83
    • 1242293704 scopus 로고    scopus 로고
    • Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats
    • Watanabe Y, Hashimoto S, Kakita A, Takahashi H, Ko J, Mizuno M et al (2004). Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats. Neurosci Res 48: 345-353.
    • (2004) Neurosci Res , vol.48 , pp. 345-353
    • Watanabe, Y.1    Hashimoto, S.2    Kakita, A.3    Takahashi, H.4    Ko, J.5    Mizuno, M.6
  • 84
    • 0007182459 scopus 로고    scopus 로고
    • Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients
    • Weike AI, Bauer U, Hamm AO (2000). Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients. Biol Psychiatry 47: 61-70.
    • (2000) Biol Psychiatry , vol.47 , pp. 61-70
    • Weike, A.I.1    Bauer, U.2    Hamm, A.O.3
  • 85
    • 0022391791 scopus 로고
    • Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38 000 characteristic of presynaptic vesicles
    • Wiedenmann B, Franke WW (1985). Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38 000 characteristic of presynaptic vesicles. Cell 41: 1017-1028.
    • (1985) Cell , vol.41 , pp. 1017-1028
    • Wiedenmann, B.1    Franke, W.W.2
  • 86
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC (1990). CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249: 1431-1433.
    • (1990) Science , vol.249 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5
  • 87
    • 0037092420 scopus 로고    scopus 로고
    • Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways
    • Yang L, Lindholm K, Konishi Y, Li R, Shen Y (2002). Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways. J Neurosci 22: 3025-3032.
    • (2002) J Neurosci , vol.22 , pp. 3025-3032
    • Yang, L.1    Lindholm, K.2    Konishi, Y.3    Li, R.4    Shen, Y.5
  • 89
    • 0037135165 scopus 로고    scopus 로고
    • Interleukin-2-induced increases in climbing behavior: Inhibition by dopamine D-1 and D-2 receptor antagonists
    • Zalcman SS (2002). Interleukin-2-induced increases in climbing behavior: inhibition by dopamine D-1 and D-2 receptor antagonists. Brain Res 944: 157-164.
    • (2002) Brain Res , vol.944 , pp. 157-164
    • Zalcman, S.S.1
  • 90
    • 0031092108 scopus 로고    scopus 로고
    • Multiparous species present problems (and possibilities) to developmentalists
    • Zorrilla EP (1997). Multiparous species present problems (and possibilities) to developmentalists. Dev Psychobiol 30: 141-150.
    • (1997) Dev Psychobiol , vol.30 , pp. 141-150
    • Zorrilla, E.P.1
  • 91
    • 0642369566 scopus 로고    scopus 로고
    • Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: A novel neurodevelopmental model of schizophrenia
    • Zuckerman L, Rehavi M, Nachman R, Weiner I (2003). Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia. Neuropsychopharmacology 28: 1778-1789.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1778-1789
    • Zuckerman, L.1    Rehavi, M.2    Nachman, R.3    Weiner, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.