The effects of an early stressful life event on sensorimotor gating in adult rats

Schizophrenia Research

Volumn 30, Issue 3, 1998, Pages 251-260

  Ellenbroek, Bart A ^a   Van Den Kroonenberg, Peter T J M ^a   Cools, Alexander R ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Early stressful life event; Neurodevelopmental hypotheses; Schizophrenia; Sensorimotor gating

Indexed keywords

HALOPERIDOL; NEUROLEPTIC AGENT; QUETIAPINE;

ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FEMALE; INFORMATION PROCESSING; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MENTAL DISEASE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PSYCHOSIS; RAT; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; SEPARATION ANXIETY; STARTLE REFLEX; STRESS;

EID: 0032502849     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(97)00149-7     Document Type: Article

References (42)

1. Bakshi, V.P., Swerdlow, N.R., Geyer, M.A., 1994. Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response. J. Pharmacol. Exp. Ther. 271, 787-794.
2. Bakshi, V.P., Geyer, M.A., 1995. Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine. Psychopharmacology 122. 198-201.
3. Braff, D.L., Stone, C., Callaway, E., Geyer, M.A., Click. I., Bali, L., 1978. Prestimulation effects on human startle reflex in normals and schizophrenics. Psychophysiology 15, 339-348.
4. Butler, R.W., Braff, D.L., Rausch, J.L., Jenkins, M.A., Sprock, J., Geyer, M.A., 1990. Psychological evidence of exaggerated startle response in a subgroup of Vietnam veterans with combat-related PTSD. Am. J. Psychiatry 147, 1308-1312.
5. Cadenhead, K.S., Geyer, M.A., Braff, D.L., 1993. Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am. J. Psychiatry 150, 1862-1867.
6. DeKloet, E.R., Rots, N.Y., Cools, A.R., 1996. Brain-corticosteroid hormone dialogue: slow and persistent. Cell. Mol. Neurobiol. 16, 345-356.
7. Ellenbroek, B.A., Cools, A.R., 1990. Animal models with construct validity for schizophrenia. Behav. Pharmacol. 1, 469-490.
8. Ellenbroek, B.A., Cools, A.R., 1995. Maternal separation reduces latent inhibition in the conditioned taste aversion paradigm. Neurosci. Res. Commun. 17, 27-33.
9. Ellenbroek, B.A., Geyer, M.A., Cools, A.R., 1995. The behavior of APO-SUS rats in animal models with construct validity for schizophrenia. J. Neurosci. 15, 7604-7611.
10. Ellenbroek, B.A., Cools, A.R., 1996. Dopamine susceptibility and information processing, In: Beninger, R.J., Palamo, T. and Archer, T. (Eds.), Dopamine Disease States. CYM, Madrid, pp. 447-462.
11. Ellenbroek, B.A., Knobbout, D.A., Cools, A.R., 1997. The role of mesolimbic and nigrostriatal dopamine in latent inhibition as measured with the conditioned taste aversion paradigm. Psychopharmacology 129, 112-120.
12. Feldon, J., Weiner, I., 1992. From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia. J. Psychiatry Res. 26, 345-366.
13. Gallegos, G., Salazar, L., Ortiz, M., Marquez, W., Davis, A., Sanchez, S., Conner, D., 1990. Simple disturbance of the dam in the neonatal period can alter haloperidol-induced catelepsy in the adult offspring. Behav. Neural Biol. 53, 172-184.
14. Geyer, M.A., Wilkinson, L.S., Humby, T., Robbins, T.W., 1993. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol. Psychiatry 34, 361-372.
15. Gray, N.S., Pilowsky, L.S., Gray, J.A., Kerwin, R.W., 1995. Latent inhibition in drug naive schizophrenics: relationship to duration of illness and dopamine D2 binding using PET. Schizophr. Res. 17, 95-107.
16. Grillon, C., Morgan, C.A., Southwick, S.M., Davis, M., Charney, D.S., 1996. Baseline startle amplitude and prepuise inhibition in Vietnam veterans with postlraumalic stress disorder. Psychiatry Res. 64, 169-178.
17. Häfner, H., Maurer, K., Löffler, W., Reichler-Rössler, A., 1993. The influence of age and sex on the onset and early course of schizophrenia. Br. J. Psychiatry 162, 80-86.
18. Hinde, R. A., Spencer-Booth, Y., 1971. Effects of brief separation from mother on rhesus monkeys. Science 173, 111-118.
19. Holer, M.A., 1970. Psychological responses of infant rats to separation from their mothers. Science 168, 871-873.
20. Johansson, C., Jackson, D.M., Svensson, L., 1994. The atypical antipsychotic remoxipride, blocks phencyclidine-induced disruption of prepulse inhibition in the rat. Psychopharmacology 116, 437-442.
21. Lipska, B.K., Weinberger, D.R., 1995. Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypy behaviours in the rat. Dev. Brain Res. 75, 213-222.
22. Lipska, B.K., Swerdlow, N.R., Geyer, M.A., Jaskiw, G.E., Braff, D.L., Weinberger, D.R., 1995. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology 122, 35-43.
23. Lubow, R.E., 1989. Latent Inhibition and Conditioned Attention Theory. Cambridge University Press, Cambridge.
24. Mansbach, R.S., Geyer, M.A., Braff, D.L., 1988. Dopaminergic stimulation disrupts motor gating in the rat. Psychopharmacology 94, 507-514.
25. Mansbach, R.S., Geyer, M.A., 1990. Efects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat. Neuropsychobiology 2, 299-308.
26. 2A antagonist MDL 100,907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats. 1996. Psychopharmacology 124, 107-116.
27. Peng, R.Y., Mansbach, R.S., Braff, D.L., Geyer, M.A., 1990. A D2 dopamine receptor agonist disrupts sensorimotor gating in rats: implications for dopaminergic abnormalities in schizophrenia. Neuropsychopharmacology 3, 211-218.
28. Pijnenburg, A., Honig, W., van Rossum, J.M., 1976. Antagonism of apomorphone-and d-amphetamine-induced stereotyped behaviour by injection of low doses of haloperidol into the caudate nucleus and the nucleus accumbens. Psychopharmacology 45, 65-71.
29. Rots, N.Y., de Jong, J., Levine, S., Cools, A.R., de Kloet, E.R., 1996. Neonatal mother-deprived rats have as adult elevated basal pituitary-adrenal activity and apomorphine susceptibility. J. Neuroendocrinol. 8, 501-506.
30. Schwarzkopf, S.B., Mitra, T., Bruno, J.P., 1992. Sensory gating in rats depleted of dopamine as neonates: potential relevance to findings in schizophrenic patients. Biol. Psychiatry 31. 759-773.
31. Swerdlow, N.R., Caine, S.B., Geyer, M.A., 1992. Regionally selective effects of intracerebral dopamine infusion in sensorimotor gating of the startle reflex in rats. Psychopharmacology 108, 189-195.
32. Swerdlow, N.R., Benbow, C.H., Sisook, S., Geyer, M.A., Braff, D.L., 1993. A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorders. Biol. Psychiatry 33, 298-301.
33. Swerdlow, N.R., Braff, D.L., Taaid, N., Geyer, M.A., 1994. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch. Gen. Psychiatry 51, 139-154.
34. Swerdiow, N.R., Paulsen, J., Braff, D.L., Butters, N., Geyer, M.A., Swenson, M.R., 1995. Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J. Neurol. Neurosurg. Psychiatry 58, 192-200.
35. Swerdlow, N.R., Bakshi, V., Geyer, M.A., 1996a. Seroquel restorse sensorimotor gating in phencyclidine-treated rats. J. Pharmacol. Exp. Ther. 279, 1290-1299.
36. Swerdlow, N.R., Braff, D.L., Hartston, H., Perry, W., Geyer, M.A., 1996b. Latent inhibition in schizophrenia. Schizophr. Res. 20, 91-103.
37. Toru, M., Shibuya, H., Mitsushio, H., Noda, K., Nishikawa, T., Ichikawa, H., Takashima, M., Malaga, M., Watanabe, S., 1984. Biochemical analysis of neurotransmitters and neuropeptides in post-mortem schizophrenic brains. Coll. Int. Neuropsychopharmacol. Abstr., p. 10.
38. Varty, G.B., Higgins, G.A., 1995. Examination of drug-induced and isolation-induced disruptions of propulse inhibition as models to screen antisychotic drugs. Psychopharmacology 122, 15-26.
39. Wan, F.J., Swerdlow, N.R., 1993. Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats. Psychopharmacology 113, 103-109.
40. Wier, P.J., Guerriero, F.J., Walker, R.F., 1989. Implementation of a primary screen for developmental neurotoxocity. Fundam. Appl. Toxicol. 13, 118-136.
41. Wilkinson, L.S., Killcross, S.S., Humby, T., Hall, F.S., Geyer, M.A., Robbins, T.W., 1994. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology 10, 61-72.
42. Zimmerberg, B., Shartrand, A.M., 1992. Temperature-dependent effects of maternal separation on growth, activity, an amphetamine sensitivity in the rat, Dev. Psychobiol. 25, 213-226.