Synthesis and potent antileukemic activities of N-lactylsphingosine and N-lactyldihydrosphingosine

Journal of Medicinal Chemistry

Volumn 46, Issue 16, 2003, Pages 3445-3447

  Azuma, Hideki ^a   Takao, Ryoko ^a   Shikata, Keiji ^a   Niiro, Hayato ^a   Tachibana, Taro ^a   Ogino, Kenji ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTILEUKEMIC AGENT; N ACETYLSPHINGOSINE; N LACTYLSPHINGOSINE; SPHINGANINE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CERAMIDES; HL-60 CELLS; HUMANS; LEUKEMIA; SPHINGOSINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0042343840     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030125p     Document Type: Article

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