메뉴 건너뛰기




Volumn 21, Issue 3, 2007, Pages 145-155

Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble [(3,5,5-trimethylhexanoyl)ferrocene]

Author keywords

Antioxidant; Ferritin; Glutathione; Hemeoxygenase; Malondialdehyde

Indexed keywords

3 NITROTYROSINE; ALPHA TOCOPHEROL; DICIFERRON; FERRITIN; FERROCENE DERIVATIVE; GAMMA TOCOPHEROL; GLUTATHIONE; HEME OXYGENASE 1; IRON; MALONALDEHYDE; UNCLASSIFIED DRUG;

EID: 34447512982     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20170     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 0030957951 scopus 로고    scopus 로고
    • Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains
    • Focht SJ, Snyder BS, Beard JL, Van Gelder W, Williams LR, Connor JR. Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains. Neuroscience 1997;79:255-261.
    • (1997) Neuroscience , vol.79 , pp. 255-261
    • Focht, S.J.1    Snyder, B.S.2    Beard, J.L.3    Van Gelder, W.4    Williams, L.R.5    Connor, J.R.6
  • 5
    • 0027430183 scopus 로고
    • Ferritin, transferrin, and iron in selected regions of the young and aged rat brain
    • Benkovic SA, Connor JR. Ferritin, transferrin, and iron in selected regions of the young and aged rat brain. J Comp Neurol 1993;338:97-113.
    • (1993) J Comp Neurol , vol.338 , pp. 97-113
    • Benkovic, S.A.1    Connor, J.R.2
  • 8
    • 0034202238 scopus 로고    scopus 로고
    • Iron as a vulnerability factor in nigrostriatal degeneration in aging and Parkinson's disease
    • Floor E. Iron as a vulnerability factor in nigrostriatal degeneration in aging and Parkinson's disease. Cell Mol Biol 2000;46:709-720.
    • (2000) Cell Mol Biol , vol.46 , pp. 709-720
    • Floor, E.1
  • 9
    • 0033045138 scopus 로고    scopus 로고
    • T1 and T2 in the brain of healthy subjects, patients with Parkinson disease, and patients with multiple system atrophy: Relation to iron content
    • Vymazal J, Righini A, Brooks RA, Canesi M, Mariani C, Leonardi M, Pezzoli G. T1 and T2 in the brain of healthy subjects, patients with Parkinson disease, and patients with multiple system atrophy: Relation to iron content. Radiology 1999;211:489-495.
    • (1999) Radiology , vol.211 , pp. 489-495
    • Vymazal, J.1    Righini, A.2    Brooks, R.A.3    Canesi, M.4    Mariani, C.5    Leonardi, M.6    Pezzoli, G.7
  • 10
    • 33748749719 scopus 로고    scopus 로고
    • Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration
    • Yokel RA. Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration. J Alzheimers Dis 2006;10:223-253.
    • (2006) J Alzheimers Dis , vol.10 , pp. 223-253
    • Yokel, R.A.1
  • 11
    • 3442895388 scopus 로고    scopus 로고
    • Hereditary haemochromatosis is unlikely to cause movement disorders - a critical review
    • Russo N, Edwards M, Andrews T, O'Brien M, Bhatia KP. Hereditary haemochromatosis is unlikely to cause movement disorders - a critical review. J Neurol 2004;251:849-852.
    • (2004) J Neurol , vol.251 , pp. 849-852
    • Russo, N.1    Edwards, M.2    Andrews, T.3    O'Brien, M.4    Bhatia, K.P.5
  • 12
    • 0034184526 scopus 로고    scopus 로고
    • Cellular distribution of ferric iron, ferritin, transferrin and divalent metal transporter 1 (DMT1) in substantia nigra and basal ganglia of normal and β2-microglobulin deficient mouse brain
    • Moos T, Trinder D, Morgan EH. Cellular distribution of ferric iron, ferritin, transferrin and divalent metal transporter 1 (DMT1) in substantia nigra and basal ganglia of normal and β2-microglobulin deficient mouse brain. Cell Mol Biol 2000;46:549-561.
    • (2000) Cell Mol Biol , vol.46 , pp. 549-561
    • Moos, T.1    Trinder, D.2    Morgan, E.H.3
  • 14
    • 0141560468 scopus 로고    scopus 로고
    • Brain barrier systems: A new frontier in metal neurotoxicological research
    • Zheng W, Aschner M, Ghersi-Egea JF. Brain barrier systems: A new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol 2003;192:1-11.
    • (2003) Toxicol Appl Pharmacol , vol.192 , pp. 1-11
    • Zheng, W.1    Aschner, M.2    Ghersi-Egea, J.F.3
  • 16
    • 1342347993 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier III. The divalent metal transporter-1 is not the major mechanism mediating brain manganese uptake
    • Crossgrove JS, Yokel RA. Manganese distribution across the blood-brain barrier III. The divalent metal transporter-1 is not the major mechanism mediating brain manganese uptake. Neurotoxicology 2004;25:451-460.
    • (2004) Neurotoxicology , vol.25 , pp. 451-460
    • Crossgrove, J.S.1    Yokel, R.A.2
  • 17
    • 0347993815 scopus 로고    scopus 로고
    • The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain
    • Moos T, Morgan EH. The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain. J Neurochem 2004;88:233-245.
    • (2004) J Neurochem , vol.88 , pp. 233-245
    • Moos, T.1    Morgan, E.H.2
  • 19
    • 1842504357 scopus 로고    scopus 로고
    • The metabolism of neuronal iron and its pathogenic role in neurological disease
    • Moos T, Morgan EH. The metabolism of neuronal iron and its pathogenic role in neurological disease. Ann NY Acad Sci 2004;1012:14-26.
    • (2004) Ann NY Acad Sci , vol.1012 , pp. 14-26
    • Moos, T.1    Morgan, E.H.2
  • 20
    • 0025993856 scopus 로고
    • Transferrin and iron uptake by the brain: Effects of altered iron status
    • Taylor EM, Crowe A, Morgan EH. Transferrin and iron uptake by the brain: Effects of altered iron status. J Neurochem 1991;57:1584-1592.
    • (1991) J Neurochem , vol.57 , pp. 1584-1592
    • Taylor, E.M.1    Crowe, A.2    Morgan, E.H.3
  • 21
    • 0036220778 scopus 로고    scopus 로고
    • The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice
    • Malecki EA, Cable EE, Isom HC, Connor JR. The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biol Trace Elem Res 2002;86:73-84.
    • (2002) Biol Trace Elem Res , vol.86 , pp. 73-84
    • Malecki, E.A.1    Cable, E.E.2    Isom, H.C.3    Connor, J.R.4
  • 23
    • 31044433625 scopus 로고    scopus 로고
    • Hepatocellular carcinoma caused by iron overload: A possible mechanism of direct hepatocarcinogenicity
    • Asare GA, Mossanda KS, Kew MC, Paterson AC, Kahler-Venter CP, Siziba K. Hepatocellular carcinoma caused by iron overload: A possible mechanism of direct hepatocarcinogenicity. Toxicology 2006;219:41-52.
    • (2006) Toxicology , vol.219 , pp. 41-52
    • Asare, G.A.1    Mossanda, K.S.2    Kew, M.C.3    Paterson, A.C.4    Kahler-Venter, C.P.5    Siziba, K.6
  • 24
    • 0034794883 scopus 로고    scopus 로고
    • Restricted transport of antitransferrin receptor antibody (OX26) through the bloodbrain barrier in the rat
    • Moos T, Morgan EH. Restricted transport of antitransferrin receptor antibody (OX26) through the bloodbrain barrier in the rat. J Neurochem 2001;79:119-129.
    • (2001) J Neurochem , vol.79 , pp. 119-129
    • Moos, T.1    Morgan, E.H.2
  • 25
    • 0026808992 scopus 로고
    • High-performance liquid chromatography with electrochemical detection for the simultaneous determination of vitamin A, D3 and E in milk
    • Delgado Zamarreno MM, Sanchez Perez A, Gomez Perez C, Hernandez Mendez J. High-performance liquid chromatography with electrochemical detection for the simultaneous determination of vitamin A, D3 and E in milk. J Chromatogr 1992;623:69-74.
    • (1992) J Chromatogr , vol.623 , pp. 69-74
    • Delgado Zamarreno, M.M.1    Sanchez Perez, A.2    Gomez Perez, C.3    Hernandez Mendez, J.4
  • 26
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 1976;74:214-226.
    • (1976) Anal Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 27
    • 0034871959 scopus 로고    scopus 로고
    • Determination of malondialdehyde dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: Comparison with UV-visible spectrophotometry
    • Lykkesfeldt J. Determination of malondialdehyde dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: Comparison with UV-visible spectrophotometry. Clin Chem 2001;47:1725-1728.
    • (2001) Clin Chem , vol.47 , pp. 1725-1728
    • Lykkesfeldt, J.1
  • 28
    • 0031959341 scopus 로고    scopus 로고
    • CNS drug design based on principles of blood-brain barrier transport
    • Pardridge WM. CNS drug design based on principles of blood-brain barrier transport. J Neurochem 1998;70:1781-1792.
    • (1998) J Neurochem , vol.70 , pp. 1781-1792
    • Pardridge, W.M.1
  • 29
    • 0032911278 scopus 로고    scopus 로고
    • Metabolism of 3,5,5-trimethylhexanoyl-ferrocene by rat liver: Release of iron from 3,5,5-trimethylhexanoyl-ferrocene by a microsomal, phenobarbital-inducible cytochrome P-450
    • Cable EE, Isom HC. Metabolism of 3,5,5-trimethylhexanoyl-ferrocene by rat liver: Release of iron from 3,5,5-trimethylhexanoyl-ferrocene by a microsomal, phenobarbital-inducible cytochrome P-450. Drug Metab Dispos 1999;27:255-260.
    • (1999) Drug Metab Dispos , vol.27 , pp. 255-260
    • Cable, E.E.1    Isom, H.C.2
  • 30
    • 0026088232 scopus 로고    scopus 로고
    • Ward RJ, Florence AL, Baldwin D, Abiaka C, Roland F, Ramsey MH, Dickson DP, Peters TJ, Crichton RR. Biochemical and biophysical investigations of the ferrocene-iron-loaded rat. An animal model of primary haemochromatosis. Eur J Biochem 1991;202:405-410.
    • Ward RJ, Florence AL, Baldwin D, Abiaka C, Roland F, Ramsey MH, Dickson DP, Peters TJ, Crichton RR. Biochemical and biophysical investigations of the ferrocene-iron-loaded rat. An animal model of primary haemochromatosis. Eur J Biochem 1991;202:405-410.
  • 31
    • 0033168171 scopus 로고    scopus 로고
    • Effects of desferrithiocin and its derivatives on peripheral iron and striatal dopamine and 5-hydroxytryptamine metabolism in the ferrocene-loaded rat
    • Dexter DT, Ward RJ, Florence A, Jenner P, Crichton RR. Effects of desferrithiocin and its derivatives on peripheral iron and striatal dopamine and 5-hydroxytryptamine metabolism in the ferrocene-loaded rat. Biochem Pharmacol 1999;58:151-155.
    • (1999) Biochem Pharmacol , vol.58 , pp. 151-155
    • Dexter, D.T.1    Ward, R.J.2    Florence, A.3    Jenner, P.4    Crichton, R.R.5
  • 32
    • 23044503950 scopus 로고    scopus 로고
    • Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
    • Cooperman SS, Meyron-Holtz EG, Olivierre-Wilson H, Ghosh MC, McConnell JP, Rouault TA. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood 2005;106:1084-1091.
    • (2005) Blood , vol.106 , pp. 1084-1091
    • Cooperman, S.S.1    Meyron-Holtz, E.G.2    Olivierre-Wilson, H.3    Ghosh, M.C.4    McConnell, J.P.5    Rouault, T.A.6
  • 33
    • 33748889489 scopus 로고    scopus 로고
    • Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice
    • Jeong SY, David S. Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice. J Neurosci 2006;26:9810-9819.
    • (2006) J Neurosci , vol.26 , pp. 9810-9819
    • Jeong, S.Y.1    David, S.2
  • 34
    • 0032228160 scopus 로고    scopus 로고
    • Modulation of age-related alterations of iron ferritin and lipid peroxidation in rat brain synaptosomes
    • Choi JH, Kim DW, Yu B. Modulation of age-related alterations of iron ferritin and lipid peroxidation in rat brain synaptosomes. J Nutr Health Aging 1998;2:133-137.
    • (1998) J Nutr Health Aging , vol.2 , pp. 133-137
    • Choi, J.H.1    Kim, D.W.2    Yu, B.3
  • 35
    • 0032078775 scopus 로고    scopus 로고
    • Iron accumulation in aging: Modulation by dietary restriction
    • Cook CI, Yu BP. Iron accumulation in aging: Modulation by dietary restriction. Mech Ageing Dev 1998;102:1-13.
    • (1998) Mech Ageing Dev , vol.102 , pp. 1-13
    • Cook, C.I.1    Yu, B.P.2
  • 36
    • 0026698175 scopus 로고
    • Studies of in vivo iron mobilization by chelators in the ferrocene-loaded rat
    • Florence A, Ward RJ, Peters TJ, Crichton RR. Studies of in vivo iron mobilization by chelators in the ferrocene-loaded rat. Biochem Pharmacol 1992;44:1023-1027.
    • (1992) Biochem Pharmacol , vol.44 , pp. 1023-1027
    • Florence, A.1    Ward, R.J.2    Peters, T.J.3    Crichton, R.R.4
  • 37
    • 0028301485 scopus 로고
    • Cellular and molecular responses in the Sprague-Dawley rat to chronic iron overload
    • Whittaker P, Chanderbhan R, Calvert R, Dunkel V. Cellular and molecular responses in the Sprague-Dawley rat to chronic iron overload. J Trace Elem Exp Med 1994;7:19-31.
    • (1994) J Trace Elem Exp Med , vol.7 , pp. 19-31
    • Whittaker, P.1    Chanderbhan, R.2    Calvert, R.3    Dunkel, V.4
  • 38
    • 0027473840 scopus 로고
    • Metabolism of iron from (3,5,5-trimethylhexanoyl) ferrocene in rats. A dietary model for severe iron overload
    • Nielsen P, Heinrich HC. Metabolism of iron from (3,5,5-trimethylhexanoyl) ferrocene in rats. A dietary model for severe iron overload. Biochem Pharmacol 1993;45:385-391.
    • (1993) Biochem Pharmacol , vol.45 , pp. 385-391
    • Nielsen, P.1    Heinrich, H.C.2
  • 39
    • 0028308427 scopus 로고    scopus 로고
    • Lambrecht RW, Cable JW, Pepe JA, Bonkovsky HL. 3,5,5- Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes. Biochem Pharmacol 1994;47:1669-1676.
    • Lambrecht RW, Cable JW, Pepe JA, Bonkovsky HL. 3,5,5- Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes. Biochem Pharmacol 1994;47:1669-1676.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.