Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 293, Issue 1, 2007, Pages

  Hua, Xiaoyang ^a   Erikson, Christopher J ^a   Chason, Kelly D ^a   Rosebrock, Craig N ^a   Deshpande, Deepak A ^b   Penn, Raymond B ^b   Tilley, Stephen L ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Knockout; Mast cell; Nerves

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; NUCLEOSIDE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); DRUG DERIVATIVE;

AIRWAY DYNAMICS; AIRWAY RESISTANCE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; CELL ACTIVATION; MOUSE; NERVE TRACT; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SENSORY NERVE CELL; ANESTHESIA; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; IN VITRO STUDY; METABOLISM; MUSCLE CONTRACTION; RESPIRATORY SYSTEM; SMOOTH MUSCLE; VAGOTOMY;

ADENOSINE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANESTHESIA; ANIMALS; BRONCHOCONSTRICTION; MICE; MICE, INBRED C57BL; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEURAL PATHWAYS; RECEPTOR, ADENOSINE A1; RESPIRATORY SYSTEM; VAGOTOMY;

EID: 34447508261     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00058.2007     Document Type: Article

References (44)

1. 3 generation in allergic rabbit airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 275: L990-L997, 1998.
2. Ali S, Mustafa SJ, Metzger WJ. Adenosine receptor-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbit model. Am J Physiol Lung Cell Mol Physiol 266: L271-L277, 1994.
3. Ali S, Mustafa SJ, Metzger WJ. Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor. J Pharmacol Exp Ther 268: 1328-1334, 1994.
4. Auchampach JA, Jin X, Wan TC, Caughey GH, Linden J. Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor. Mol Pharmacol 52: 846-860, 1997.
5. Bjorck T, Gustafsson LE, Dahlen SE. Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine. Am Rev Respir Dis 145: 1087-1091, 1992.
6. Carr MJ, Goldie RG, Henry PJ. Influence of respiratory tract viral infection on endothelin-1-induced potentiation of cholinergic nerve-mediated contraction in mouse trachea. Br J Pharmacol 119: 891-898, 1996.
7. 2A receptors activating single vagal sensory C-fibres in guinea pig lungs. J Physiol 575: 481-490, 2006.
8. Csoma Z, Huszar E, Vizi E, Vass G, Szabo Z, Herjavecz I, Kollai M, Horvath I. Adenosine level in exhaled breath increases during exercise-induced bronchoconstriction. Eur Respir J 25: 873-878, 2005.
9. Cushley MJ, Tattersfield AE, Holgate ST. Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 15: 161-165, 1983.
10. Driver AG, Kukoly CA, Ali S, Mustafa SJ. Adenosine in bronchoalveolar lavage fluid in asthma. Am Rev Respir Dis 148: 91-97, 1993.
11. Ethier MF, Madison JM. Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells. Am J Respir Cell Mol Biol 35: 496-502, 2006.
12. Feoktistov I, Biaggioni I. Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96: 1979-1986, 1995.
13. Feoktistov I, Ryzhov S, Goldstein AE, Biaggioni I. Mast cell-mediated stimulation of angiogenesis: cooperative interaction between A2B and A3 adenosine receptors. Circ Res 92: 485-492, 2003.
14. Forsythe P, Ennis M. Adenosine, mast cells and asthma. Inflamm Res 48: 301-307, 1999.
15. Gerwins P, Fredholm BB. Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells. Proc Natl Acad Sci USA 89: 7330-7334, 1992.
16. Gimenez-Llort L, Fernandez-Teruel A, Escorihuela RM, Fredholm BB, Tobena A, Pekny M, Johansson B. Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. Eur J Neurosci 16: 547-550, 2002.
17. Gu Q, Ruan T, Hong JL, Burki N, Lee LY. Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats. J Appl Physiol 95: 1315-1324; discussion 1314, 2003.
18. Hua X, Kovarova M, Chason KD, Nguyen M, Koller BH, Tilley SL. Enhanced mast cell activation in mice deficient in the A2b adenosine receptor. J Exp Med 204: 117-128, 2007.
19. Huszar E, Vass G, Vizi E, Csoma Z, Barat E, Molnar Vilagos G, Herjavecz I, Horvath I. Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma. Eur Respir J 20: 1393-1398, 2002.
20. Ito Y, Izumi H, Sato M, Karita K, Iwatsuki N. Suppression of parasympathetic reflex vasodilatation in the lower lip of the cat by isoflurane, propofol, ketamine and pentobarbital: implications for mechanisms underlying the production of anaesthesia. Br J Anaesth 81: 563-568, 1998.
21. Jacobson KA, Gao ZG. Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 5: 247-264, 2006.
22. Joad JP, Kott KS. Effect of adenosine receptor ligands on cAMP content in human airways and peripheral lung. Am J Respir Cell Mol Biol 9: 134-140, 1993.
23. Keir S, Boswell-Smith V, Spina D, Page C. Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. Br J Pharmacol 147: 720-728, 2006.
24. Kwong K, Hong JL, Morton RF, Lee LY. Role of pulmonary C fibers in adenosine-induced respiratory inhibition in anesthetized rats. J Appl Physiol 84: 417-424, 1998.
25. Ledent C, Vaugeois JM, Schiffmann SN, Pedrazzini T, El Yacoubi M, Vanderhaeghen JJ, Costentin J, Heath JK, Vassart G, Parmentier M. Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature 388: 674-678, 1997.
26. Manzini S, Ballati L. 2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea-pigs. Br J Pharmacol 100: 251-256, 1990.
27. Martin GR, Gerard NP, Gallis J, Drazen JM. Pulmonary responses to bronchoconstrictor agonists in the mouse. J Appl Physiol 64: 2318-2323, 1988.
28. Martin TR, Takeishi T, Katz HR, Austen KF, Drazen JM, Galli SJ. Mast cell activation enhances airway responsiveness to methacholine in the mouse. J Clin Invest 91: 1176-1182, 1993.
29. Meade CJ, Mierau J, Leon I, Ensinger HA. In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells. J Pharmacol Exp Ther 279: 1148-1156, 1996.
30. 1 receptors on cardiac vagal afferents in adult rats. Am J Physiol Heart Circ Physiol 274: H441-H447, 1998.
31. Mundell SJ, Olah ME, Panettieri RA, Benovic JL, Penn RB. Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine. Am J Respir Cell Mol Biol 24: 155-163, 2001.
32. Nyce JW, Metzger WJ. DNA antisense therapy for asthma in an animal model. Nature 385: 721-725, 1997.
33. Oosterhoff Y, de Jong JW, Jansen MA, Koeter GH, Postma DS. Airway responsiveness to adenosine 5′-monophosphate in chronic obstructive pulmonary disease is determined by smoking. Am Rev Respir Dis 147: 553-558, 1993.
34. Phillips GD, Polosa R, Holgate ST. The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma. Clin Exp Allergy 19: 405-409, 1989.
35. Phillips GD, Scott VL, Richards R, Holgate ST. Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5′-monophosphate. Eur Respir J 2: 210-217, 1989.
36. Polosa R, Ciamarra I, Mangano G, Prosperini G, Pistorio MP, Vancheri C, Crimi N. Bronchial hyperresponsiveness and airway inflammation markers in nonasthmatics with allergic rhinitis. Eur Respir J 15: 30-35, 2000.
37. Polosa R, Phillips GD, Rajakulasingam K, Holgate ST. The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5′-monophosphate and histamine in asthma. J Allergy Clin Immunol 87: 939-947, 1991.
38. 3 adenosine receptor gene in mice and its effect on stimulated inflammatory cells. J Biol Chem 275: 4429-4434, 2000.
39. Sandrasagra A, Leonard SA, Tang L, Teng K, Li Y, Ball HA, Mannion JC, Nyce JW. Discovery and development of respirable antisense therapeutics for asthma. Antisense Nucleic Acid Drug Dev 12: 177-181, 2002.
40. 2 on airway tone. Am J Physiol Lung Cell Mol Physiol 284: L599-L606, 2003.
41. Tilley SL, Tsai M, Williams CM, Wang ZS, Erikson CJ, Galli SJ, Koller BH. Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice. J Immunol 171: 331-337, 2003.
42. 3 receptors on mast cells. J Clin Invest 105: 361-367, 2000.
43. Tournoy KG, De Swert KO, Leclere PG, Lefebvre RA, Pauwels RA, Joos GF. Modulatory role of tachykinin NK1 receptor in cholinergic contraction of mouse trachea. Eur Respir J 21: 3-10, 2003.
44. Zhong H, Shlykov SG, Molina JG, Sanborn BM, Jacobson MA, Tilley SL, Blackburn MR. Activation of murine lung mast cells by the adenosine A3 receptor. J Immunol 171: 338-345, 2003.