Lipopolysaccharide dependent cellular activation

Journal of Periodontal Research

Volumn 32, Issue 1 PART 2, 1997, Pages 99-103

  Tobias, P S ^a   Gegner, J ^a   Tapping, R ^a   Orr, S ^a   Mathison, J ^a   Lee, J D ^a   Kravchenko, V ^a   Han, J ^a   Ulevitch, R J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cellular activation; Lipopolysaccharide

Indexed keywords

ACUTE PHASE PROTEIN; CARRIER PROTEIN; CD14 ANTIGEN; CYTOKINE; GLYCERYLPHOSPHOINOSITOL; INOSITOL PHOSPHATE; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; PLASMA PROTEIN;

ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENDOTHELIUM; ENDOTOXEMIA; HUMAN; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; PROTEIN BINDING; REVIEW; SIGNAL TRANSDUCTION; STIMULATION; TRANSACTIVATION;

ACUTE-PHASE PROTEINS; ANIMALS; ANTIGENS, CD14; BLOOD PROTEINS; CARRIER PROTEINS; CYTOKINES; ENDOTHELIUM; ENDOTOXEMIA; HUMANS; INOSITOL PHOSPHATES; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; TRANS-ACTIVATION (GENETICS);

EID: 0030628111     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.1997.tb01388.x     Document Type: Article

References (40)

1. Goyert SM, Ferrero EM, Seremetis SV, Winchester RJ, Silver J, Mattison AC. Biochemistry and expression of myelomonocytic antigens. J Immunol 1986; 137: 3909-3914.
2. Camussi G, Mariano F, Biancone L, et al. Lipopolysaccharide binding protein and CD14 modulate the synthesis of platelet-activating factor by human monocytes and mesangial and endothelial cells stimulated with lipopolysaccharide. J Immunol 1995; 155: 316-324.
3. Fearns C, Kravchenko VV, Ulevitch RJ, Loskutoff DJ. Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide. J Exp Med 1995; 181: 857-866.
4. Pugin J, Schurer-Maly C-C, Leturcq D, Moriarty A, Ulevitch RJ, Tobias PS. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc Natl Acad Sci USA 1993; 90: 2744-2748.
5. Loppnow H, Stelter F, Schonbeck U, et al. Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14. Infect Immun 1995; 63: 1020-1026.
6. Frey EA, Miller DS, Jahr TG, et al. Soluble CD14 participates in the response of cells to lipopolysaccharide. J Exp Med 1992; 176: 1665-1671.
7. Mathison JC, Tobias PS, Wolfson E, Ulevitch RJ. Plasma lipopolysaccharide (LPS)-binding protein: a key component in macrophage recognition of Gram-negative LPS. J Immunol 1992; 149. 200-206.
8. Gegner JA, Ulevitch RJ, Tobias PS. LPS signal transduction and clearance. Dual roles for LBP and mCD14. J Biol Chem 1995; 270: 5320-5325.
9. Rietschel ET, Brade H. Bacterial endotoxins. Sci Am 1992; 267: 54-61.
10. Rietschel ET, Kirikae T, Schade FU, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J 1994; 8: 217-225.
11. Hamada S, Fujiwara T, Mihara J. Bacterial endotoxic substances and their effects on host cells. In: Genco R, Hamada S, Lehner T, McGhee J, Mergenhagen S, eds. Molecular pathogenesis of peridontal disease. Washington DC, ASM Press, 1994: 105-117.
12. Takayama K, Mitchell DH, Din ZZ, Mukerjee P, Li C, Coleman DL. Monomeric Re lipopolysaccharide from Escherichia coli is more active than the aggregated form in the Limulus amebocyte lysate assay and in inducing Egr-1 mRNA in murine peritoneal macrophages. J Biol Chem 1994; 269: 2241-2244.
13. Brandenburg K, Mayer H, Koch MHJ, Weckesser J, Rietschel ET, Seydel U. Influence of the supramolecular structure of free lipid A on its biological activity. Eur J Biochem 1993; 218: 555-563.
14. Takayama K, Din ZZ, Mukerjee P, Cooke PH, Kirkland TN. Physicochemical properties of the lipopolysaccharide unit that activates B lymphocytes J Biol Chem 1990; 265: 14023-14029.
15. Wang D, Pabst KM, Aida Y, Pabst MJ. Lipopolysaccharide-inactivating activity of neutrophils is due to lactoferrin. J Leuk Biol 1995; 57: 865-874.
16. Wurfel MM, Kunitake ST, Lichenstein H, Kane JP, Wright SD. Lipopolysaccharide ( LPS )-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med 1994; 180: 1025-1035.
17. Ulevitch RJ, Johnston AR, Weinstein DB. New function for high density lipoproteins. Their participation in intravascular reactions of bacterial lipopolysaccharides. J Clin Invest 1979; 64: 1516-1524.
18. Quezado ZM, Natanson C, Banks SM, et al. Therapeutic trial of reconstituted human high-density lipoprotein in a canine model of gram-negative septic shock. J Pharm Exp Ther 1995; 272: 604-611.
19. Parker TS, Levine DM, Chang JC, Laxer J, Coffin CC, Rubin AL. Reconstituted high-density lipoprotein neutralizes Gram-negative bacterial lipopolysaccharides in human whole blood. Infect Immun 1995; 63: 253-258.
20. Schumann RR, Leong SR, Flaggs GW, et al. Structure and function of lipopolysaccharide (LPS) binding protein; a plasma protein that controls the response of macrophages to LPS. Science 1990; 249: 1429-1431.
21. Ulevitch RJ, Tobias PS. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin [review]. Ann Rev Immunol 1995; 13: 437-457.
22. Mészáros K, Parent JB, Gazzano-Santoro H, et al. A recombinant amino terminal fragment of bactericidal/permeability-increasing protein inhibits the induction of leukocyte responses by LPS. J Leuk Biol 1993; 54: 558-563.
23. Tobias PS, Soldau K, Ulevitch RJ. Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J Biol Chem 1989; 264: 10867-10871.
24. Martin TR, Mathison JC, Tobias PS, et al. Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs. J Clin Invest 1992; 90: 2209-2219.
25. Gallay P, Heumann D, Le Roy D, Barras C, Glauser MP. Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock. Proc Natl Acad Sci USA 1993; 90: 9935-9938.
26. Han J, Mathison J, Ulevitch R, Tobias P. Lipopolysaccharide (LPS) binding protein, truncated at Ile-197, binds LPS but does not transfer LPS to CD14. J Biol Chem 1994; 269: 8172-8175.
27. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD14 serves as the cellular receptor for complexes of lipopolysaccharide with lipopolysaccharide binding protein. Science 1990; 249: 1431-1433.
28. Haziot A, Chen S, Ferrero E, Low MG, Silber R, Goyert SM. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage. J Immunol 1988; 141: 547-552.
29. Maliszewski CR, Ball ED, Graziano RF, Fanger MW. Isolation and characterization of My23, a myeloid cell-derived antigen reactive with the monoclonal antibody AML-2-23. J Immunol 1985; 135: 1929-1936.
30. Leturcq DJ, Moriarty AM, Winn RJ, Talbott G, Martin TR, Ulevitch' RJ. Therapeutic strategies to block LPS interactions with its receptor. Intensive Care Med 1994; 20(abstr): S146.
31. Juan TS, Hailman E, Kelley MJ, Wright SD, Lichenstein HS. Identification of a domain in soluble CD14 essential for lipopolysaccharide (LPS) signaling but not LPS binding. J Biol Chem 1995; 270: 17237-17242.
32. Viriyakosol S, Kirkland TN. A region of human CD14 required for lipopolysaccharide binding. J Biol Chem 1995; 270: 361-368.
33. Haziot A, Rong GW, Lin XY, Silver J, Goyert SM. Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide). J Immunol 1995; 154: 6529-6532.
34. Pugin J, Ulevitch RJ, Tobias PS. Tumor necrosis factoralpha and interleukin 1-beta mediate human endothelial cell activation in blood at low endotoxin concentrations. J Inflamm 1995; 45: 49-55.
35. Pugin J, Heumann D, Tomasz A, et al. CD14 is a pattern recognition receptor. Immunity 1995; 1: 509-516.
36. Zhang Y, Doerfler M, Lee TC, Guillemin B, Rom WN. Mechanisms of stimulation of interleukin-1β and tumor necrosis factor-α by Mycobacterium tuberculosis components. J Clin Invest 1993; 91: 2076-2083.
37. Lee J-D, Kravchenko V, Kirkland TN, et al. Glycosylphosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin. Proc Natl Acad Sci USA 1993; 90: 9930-9934.
38. Levine DM, Parker TS, Donnelly TM, Walsh A, Rubin AL. In vivo protection against endotoxin by plasma high density lipoprotein. Proc Natl Acad Sci USA 1993; 90: 12040-12044.
39. A inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo. J Exp Med 1990; 172: 77-84.
40. Christ WJ, Asano O, Robidoux AL, et al. E5531, a pure endotoxin antagonist of high potency. Science 1995; 268: 80-83.