Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia

Journal of Neurochemistry

Volumn 102, Issue 3, 2007, Pages 667-678

  Zhou, Yan ^a   Ling, Eng Ang ^a   Dheen, S Thameem ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Glucocorticoids; Jun N terminal kinase; Microglia; Mitogen activated protein kinase phosphatase 1; Monocyte chemoattractant protein 1; Neuroinflammation; p38

Indexed keywords

DEXAMETHASONE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; STRESS ACTIVATED PROTEIN KINASE; TRIPTOLIDE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOCYTOCHEMISTRY; MICROGLIA; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN; CELL CYCLE PROTEINS; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOTAXIS; COCULTURE TECHNIQUES; DEXAMETHASONE; DOWN-REGULATION; ENCEPHALITIS; IMMEDIATE-EARLY PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MICROGLIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RATS, WISTAR; TREATMENT OUTCOME;

RATTUS;

EID: 34447331410     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04535.x     Document Type: Article

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