Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines

Endocrinology

Volumn 144, Issue 2, 2003, Pages 412-422

  Engelbrecht, Y ^a   De Wet, H ^a   Horsch, K ^a   Langeveldt, C R ^a   Hough, F S ^a   Hulley, P A ^a,b  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN INDUCTION;

ANIMALS; BLOOD PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CYTOSOL; DEXAMETHASONE; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, IMMEDIATE-EARLY; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MIFEPRISTONE; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOBLASTS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; TRANS-ACTIVATION (GENETICS); UP-REGULATION;

EID: 0037320305     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220769     Document Type: Article

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