Evaluation of T cell immune responses in multi-drug-resistant tuberculosis (MDR-TB) patients to Mycobacterium tuberculosis total lipid antigens

Clinical and Experimental Immunology

Volumn 149, Issue 2, 2007, Pages 285-294

  Shahemabadi, A S ^a   Hosseini, A Zavaran ^a   Shaghsempour, S ^b   Masjedi, M R ^b   Rayani, M ^b   Pouramiri, M ^c  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Interferon gamma; Interleukin 4; Multi drug resistant tuberculosis; T cells; Total lipid antigens

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BACTERIAL ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; TUBERCULIN;

ADULT; ANALYTIC METHOD; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; HUMAN; IMMUNE RESPONSE; MALE; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULIN TEST; TUBERCULOSIS;

ADULT; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-4; LIPIDS; MALE; MIDDLE AGED; T-LYMPHOCYTE SUBSETS; TUBERCULIN; TUBERCULIN TEST; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 34447321027     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03406.x     Document Type: Article

References (42)

1. Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC. Consensus statement: global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance Monitoring Project. JAMA 1999 282 : 677 86.
2. Dye C. Global epidemiology of tuberculosis. Lancet 2006 307 : 938 40.
3. Sharma SK, Mohan A. Multidrug-resistant tuberculosis. Indian J Med Res 2004 120 : 354 76.
4. Iseman MD. Treatment of multi-drug resistant tuberculosis. N Engl J Med 1993 329 : 784 91.
5. Dye C, Williams BG, Espinal MA, Raviglione MC. Erasing the world's slow stain: strategies to beat multidrug-resistant tuberculosis. Science 2002 295 : 2042 3.
6. World Health Organization (WHO). Interim Policy on Collaborative TB/HIV Activities. WHO/HTM/TB/2004.330; WHO /HTM/HIV/2004/1. Geneva : WHO, 2004.
7. Flynn JL, Ernst JD. Immune responses in tuberculosis. Curr Opin Immunol 2000 12 : 432 6.
8. Scanga CA, Mohan VP, Yu K et al. Depletion of CD4 T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2. J Exp Med 2000 192 : 347 58.
9. Ulrichs T, Porcelli SA. CD1 proteins: targets of T cell recognition in innate and adaptive immunity. Rev Immunogenet 2000 2 : 416 32.
10. Porcelli SA, Modlin RL. The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu Rev Immunol 1999 17 : 297 29.
11. Sieling PA, Chatterjee D, Porcelli SA et al. CD1-restricted T cell recognition of microbial lipoglycans. Science 1995 269 : 227 30.
12. Gumperz JE, Brenner MB. CD1-specific T cells in microbial immunity. Curr Opin Immunol 2001 13 : 471 8.
13. Romani N, Gruner S, Brang D et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994 180 : 83 93.
14. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor. J Exp Med 1994 179 : 1109 18.
15. Moody DB, Young DC, Cheng TY et al. T cell activation by lipopeptide antigens. Science 2004 303 : 527 31.
16. Ulrichs T, Moody DB, Grant E, Kaufmann SHE, Porcelli SA. T cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection. Infect Immun 2003 71 : 3076 87.
17. Dascher CC, Hiromatsu K, Xiong X et al. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis. Int Immunol 2003 15 : 915 25.
18. Manca C, Reed MB, Freeman S et al. Differential monocyte activation underlies strain-specific Mycobacterium tuberculosis pathogenesis. Infect Immu 2004 79 : 5511 14.
19. Dao DN, Kremer L, Gue'rardel Y et al. Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages. Infect Immun 2004 72 : 2067 74.
20. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957 226 : 497 509.
21. Hochstenbach F, Parker C, McLean J et al. Characterization of a third form of the human T cell receptor gamma/delta. J Exp Med 1988 168 : 761 76.
22. Blum H, Beier H, Gross HJ. Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis 1987 8 : 93 101.
23. Moody DB, Guy MR, Grant E et al. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. J Exp Med 2000 192 : 965 32.
24. Seah GT, Rook GAW. IL-4 influences apoptosis of Mycobacterium-reactive lymphocytes in the presence of TNF-α. J Immunol 2001 167 : 1230 7.
25. Brennan PJ. Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis. Tuberculosis 2003 83 : 91 7.
26. Feng CG, Bean AGD, Hooi H, Briscoe H, Britton WJ. Increase in gamma interferon-secreting CD8, as well as CD4 T cells in lungs following aerosol infection with Mycobacterium tuberculosis. Infect Immun 1999 67 : 3242 7.
27. Mogues T, Goodrich ME, Ryan L, LaCourse R, North RJ. The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice. J Exp Med 2001 193 : 271 80.
28. Tascon RE, Stavropoulos E, Lukacs KV, Colston MJ. Protection against M. tuberculosis infection by CD8 T cells requires production of gamma interferon. Infect Immun 1998 66 : 830 4.
29. Moody DB, Ulrichs T, Muhlecker W et al. CD1c-mediated T cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 2000 404 : 884.
30. Zhang M, Lin Y, Lyer DR, Gong J, Abrams JS, Barne PF. T cell cytokine responses in human infection with M. tuberculosis. Infect Immun 1995 63 : 3231 4.
31. Lee JS, Song CH, Kim CH et al. Profiles of IFN-γ and its regulatory cytokines (IL-12, IL-18 and IL-10) in peripheral blood mononuclear cells from patients with multidrug-resistant tuberculosis. Clin Exp Immunol 2002 128 : 516 24.
32. Dlugovitzky D, Bay ML, Rateni L et al. Influence of disease severity on nitrite and cytokine reduction by peripheral blood mononuclear cells (PBMC) from patients with pulmonary tuberculosis (TB). Clin Exp Immunol 2000 122 : 343 9.
33. Kim J, Uyemura K, Van Dyke MK et al. A role for IL-12 receptor expression and signal transduction in host defense in leprosy. J Immunol 2001 167 : 779 86.
34. Stenger S, Niazi KR, Modlin RL. Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. J Immunol 1998 161 : 3582 8.
35. Song CH, Kim HJ, Park JK et al. Depressed IL-12, but not IL-18 production in response to a 30- and 32-kDa mycobacterial antigen in patients with active pulmonary tuberculosis. Infect Immun 2000 68 : 4477 84.
36. Jo EK, Kim HJ, Lim JH et al. Dysregulated production of interferon gamma, interleukin-4 and interleukin-6 in early tuberculosis patients in response to antigen 85B of Mycobacterium tuberculosis. Scand J Immunol 2000 51 : 209 17.
37. Seah GT, Scott GM, Rook GAW. Type-2 cytokine gene activation and its relationship to the extent of disease in patients with tuberculosis. J Infect Dis 2000 181 : 385 92.
38. Hirsch CG, Toossi Z, Vanham G et al. Apoptosis and T cell hyporesponsiveness in pulmonary tuberculosis. J Infect Dis 1999 179 : 945 54.
39. Bai X, Wilson SE, Chmura K, Feldman NE, Chan ED. Morphometric analysis of Th1 and Th2 cytokine expression in human pulmonary tuberculosis. Tuberculosis 2004 84 : 375 85.
40. Van Crevel R, Karyadi E, Preyers F et al. Increased production of interleukin 4 by CD4 and CD8T cells from patients with tuberculosis is related to the presence of pulmonary cavities. J Infect Dis 2000 181 : 1194 8.
41. Sugawara I, Yamada H, Mizuno S, Iwakura Y. IL-4 is required for defense against mycobacterial infection. Microbiol Immunol 2000 44 : 971 9.
42. Smith SM, Klein MR, Malin AS, Sillah J, McAdam WMP, Dockrell M. Decreased IFN-γ and increased IL-4 production by human CD8+ T cells in response to Mycobacterium tuberculosis in tuberculosis patients. Tuberculosis 2002 82 : 7 13.