Increased production of interleukin 4 by CD4+ and CD8+ T cells from patients with tuberculosis is related to the presence of pulmonary cavities

Journal of Infectious Diseases

Volumn 181, Issue 3, 2000, Pages 1194-1197

  Van Crevel, Reinout ^a   Karyadi, Elvina ^b   Preyers, Frank ^a   Leenders, Marij ^a   Kullberg, Bart Jan ^a   Nelwan, Ronald H H ^b   Van Der Meer, Jos W M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF INDONESIA   (Indonesia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4;

ADOLESCENT; ADULT; AGED; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; HOST RESISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LUNG CAVITY; LUNG TUBERCULOSIS; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; TISSUE INJURY;

ADOLESCENT; ADULT; AGED; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; MALE; MIDDLE AGED; TUBERCULOSIS, PULMONARY;

EID: 0034113481     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315325     Document Type: Article

References (15)

1. 1. I. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic and inflammatory diseases. Clin Microbiol Rev 1996; 9:532-62.
2. 2. Surcel HM, Troye Blomberg M, Paulie S, et al. Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens. Immunology 1994; 81:171-6.
3. 3. Sanchez FO, Rodriguez JI, Garcia LF. Immune responsiveness and lymphokine production in patients with tuberculosis and healthy controls. Infect Immun 1994; 62:5673-8.
4. 4. Zhang M, Lin Y, Iyer DV, Gong J, Abrams JS, Barnes PF. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun 1995; 63:3231-4.
5. 5. Lin Y, Zhang M, Hofman FM, Gong J, Barnes PF. Absence of a prominent Th2 cytokine response in human tuberculosis. Infect Immun 1996; 64: 1351-6.
6. 6. Ottenhoff THM, Kumararatne D, Casanova JL. Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria. Immunology Today 1998; 19:491-4.
7. 7. Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 1993; 178:2249-54.
8. 8. Hernandez Pando R, Orozco H, Sampieri A, et al. Correlation between the kinetics of Th1/Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis. Immunology 1996; 89:26-33.
9. 9. Lukacs NW, Addison CL, Gauldie J, et al. Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1 type pulmonary granulomas. J Immunol 1997; 158:4478-84.
10. 10. Jung NG T, Schauer U, Heusser C, Neumann C, Rieger C. Detection of intracellular cytokines by flow cytometry. J Immunol Methods 1993; 159: 197-207.
11. 11. Solbach W. Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sezary) T helper lymphocytes. J Exp Med 1982; 156:1250-6.
12. + T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells. J Exp Med 1998; 187: 1633-40.
13. + T cells in purified protein derivative-positive, but not in purified protein derivative-negative subjects. J Immunol 1998; 160:2408-17.
14. 14. Yu CT, Wang CH, Huang TJ, Lin HC, Kuo HP. Relation of bronchoalveolar lavage T lymphocyte subpopulalions to rate of regression of active pulmonary tuberculosis. Thorax 1995; 50:869-74.
15. 15. Atamas SP, Choi J, Yurovsky VV, White B. An alternative splice variant of human IL-4, IL-4 delta 2, inhibits IL-4-stimulated T-cell proliferation. J Immunol 1996; 156: 435-41.