Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol

Journal of Membrane Biology

Volumn 214, Issue 3, 2006, Pages 123-129

  Teisseyre, Andrzej ^a   Michalak, Krystyna ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Cancer cell proliferation; Lymphocyte proliferation; Patch clamp; Potassium channel; Resveratrol; T lymphocyte

Indexed keywords

POTASSIUM CHANNEL KV1.3; RESVERATROL;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LYMPHOCYTE; PATCH CLAMP; PROTEIN EXPRESSION;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENISTEIN; HUMANS; KV1.3 POTASSIUM CHANNEL; LYMPHOCYTES; MEMBRANE POTENTIALS; STILBENES; TIME FACTORS;

EID: 34447312220     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-007-0043-8     Document Type: Article

References (28)

1. Abdul M., Hoosein N. 2002. Expression and activity of potassium ion channels in human prostate cancer. Cancer Lett. 186:99-105
2. Abdul M., Santo A., Hoosein N. 2003. Activity of potassium channel-blockers in breast cancer. Anticancer Res. 23:3347-3351
3. Baur J.A., Sinclair D.A. 2006. Therapeutic potential of resveratrol: The in vivo evidence. Nat. Rev. Drug Discov. 5:493-506
4. Cahalan M., Wulff H., Chandy K.G. 2001. Molecular properties and physiological roles of ion channels in the immune system. J. Clin. Immunol. 21:235-252
5. + channel as targets for specific immunomodulation. Trends Pharmacol. Sci. 25:280-289
6. Chung I., Schlichter L. 1997. Native Kv1.3 channels are upregulated by protein kinase C. J. Membr. Biol. 156:73-85
7. + channels for cancer therapy. Exp. Ther. Oncol. 4:161-166
8. Delmas D., Lancon A., Colin D., Jannin B., Latruffe N. 2006. Resveratrol as a chemopreventive agent: A promising molecule for fighting cancer. Curr. Drug Targets 7:423-442
9. Felipe A., Vincente R., Villalonga N., Roura-Ferrer M., Martinez-Marmol R., Sole L., Ferres J., Condom E. 2006. Potassium channels: New targets in cancer therapy. Cancer Detect. Prev. 30:375-385
10. Fremont L. 2000. Minireview. Biological effects of resveratrol. Life Sci. 66:663-673
11. Grandos-Soto V., Arguelles C.F., Ortiz M.I. 2002. The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels. Neuropharmacology 43:917-923
12. Grissmer S., Nguyen A., Cahalan M. 1993. Calcium-activated potassium channels in resting and activated human T lymphocytes. J. Gen. Physiol. 102:601-630
13. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch. 39:85-100
14. Han Y., Zheng W., Bastianetto S., Chabot J., Quirion R. 2004. Neuroprotective effects of resveratrol against β-amyloid-induced neurotoxicity in rat hippocampal neurons: Involvement of protein kinase C. Br. J. Pharmacol. 141:997-1005
15. Hirano T., Kuritani T., Kishimoto Y., Yamamura Y. 1977. T cell dependency of PWM-induced Ig production by B cells. J. Immunol. 119:1235
16. Hu G., Gao Z. 2005. Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons. Brain Res. 1056:68-75
17. + current in vascular endothelial cells. Cardiovasc. Res. 45:1035-1045
18. Michalak K., Teisseyre A., Łania-Pietrzak B. 2005. Inhibition of multidrug resistance-associated protein MRP and Kv channels by natural polyphenols. Eur. Biophys. J./Biophys. Lett. 34:805, abstract P-875
19. Orsini F., Verotta L., Lecchi M., Restano R., Curia G., Redaelli E., Wanke E. 2004. Resveratrol derivatives and their role as potassium channel modulators. J. Nat. Prod. 67:421-426
20. Panyi G., Gaspar R., Krasznai J., Ameloot M., Aszalos A., Steels P., Damjanovich S. 1996. Immunosuppressors inhibit voltage-gated potassium channels in human peripheral blood lymphocytes. Biochem. Biophys. Res. Commun. 221:254-258
21. Pardo LA. 2004. Voltage-gated potassium channels in cell proliferation. Physiology (Bethesda) 19:285-292
22. Rouzaire-Dubois B., Dubois JM. 1990. Tamoxifen blocks both proliferation and voltage-dependent K channels of neuroblastoma cells. Cell. Signal. 2:387-393
23. Rouzaire-Dubois B., Gerard V., Dubois J.M. 1993. Involvement of K channels in quercetin-induced inhibition of neuroblastoma cell growth. Pfluegers Arch. 423:202-205
24. + channel gating. Mol. Pharmacol. 59:1376-1387
25. Teisseyre A., Michalak K. 2005. Genistein inhibits the activity of Kv1.3 potassium channels in human T lymphocytes. J. Membr. Biol. 205:71-79
26. Teisseyre A., Mozrzymas J.W. 2002. Inhibition of the activity of T lymphocyte Kv1.3 channels by extracellular zinc. Biochem. Pharmacol. 64:595-607
27. + channels in regulating tumour cell proliferation and apoptosis. Pfluegers Arch. 448:274-286
28. Zhang Y., Liu Y., Wang T., Li B., Li H., Wang Z., Baofeng Y. 2006. Resveratrol, a natural ingredient of grape skin: Antiarrythmic efficacy and ionic mechanisms. Biochem. Biophys. Res. Commun. 340:1192-1199