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Volumn 66, Issue 7, 2007, Pages 566-575

The morphogen signaling network in forebrain development and holoprosencephaly

Author keywords

Anterior neural border; Forebrain patterning; Middle interhemispheric variant; Organizer; Prechordal plate; Roof plate

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; CHORDIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 8; MORPHOGEN; NOGGIN; PROTEIN; PROTEIN NODAL; PROTEIN TWISTED; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR SIX3; TRANSCRIPTION FACTOR ZIC2; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 34447304887     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/nen.0b013e3180986e1b     Document Type: Review
Times cited : (55)

References (80)
  • 2
    • 0034107360 scopus 로고    scopus 로고
    • Genetics of ventral forebrain development and holoprosencephaly
    • Muenke M, Beachy PA. Genetics of ventral forebrain development and holoprosencephaly. Curr Opin Genet Dev 2000;10:262-69
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 262-269
    • Muenke, M.1    Beachy, P.A.2
  • 3
    • 0031728633 scopus 로고    scopus 로고
    • Holoprosencephaly: A defect in brain patterning
    • Golden JA. Holoprosencephaly: A defect in brain patterning. J Neuropathol Exp Neurol 1998;57:991-99
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 991-999
    • Golden, J.A.1
  • 5
    • 33748129210 scopus 로고    scopus 로고
    • Midline patterning defects
    • Golden JA, Harding B, eds, Basel: International Society for Neuropathology (ISN) Neuropath Press
    • Ming JE, Golden JA. Midline patterning defects. In: Golden JA, Harding B, eds. Developmental Neuropathology, Vol. 4. Basel: International Society for Neuropathology (ISN) Neuropath Press, 2004:386
    • (2004) Developmental Neuropathology , vol.4 , pp. 386
    • Ming, J.E.1    Golden, J.A.2
  • 6
    • 33749472755 scopus 로고    scopus 로고
    • Holoprosencephaly: Clinical, anatomic, and molecular dimensions. Birth Defects Res A Clin Mol
    • Cohen MM Jr. Holoprosencephaly: Clinical, anatomic, and molecular dimensions. Birth Defects Res A Clin Mol Teratol 2006;76:658-73
    • (2006) Teratol , vol.76 , pp. 658-673
    • Cohen Jr., M.M.1
  • 7
    • 0027158534 scopus 로고
    • Middle interhemispheric fusion: An unusual variant of holoprosencephaly
    • Barkovich AJ, Quint DJ. Middle interhemispheric fusion: An unusual variant of holoprosencephaly. Am J Neuroradiol 1993;14:431-40
    • (1993) Am J Neuroradiol , vol.14 , pp. 431-440
    • Barkovich, A.J.1    Quint, D.J.2
  • 8
    • 0036153378 scopus 로고    scopus 로고
    • The middle interhemispheric variant of holoprosencephaly
    • Simon EM, Hevner RF, Pinter JD, et al. The middle interhemispheric variant of holoprosencephaly. Am J Neuroradiol 2002;23:151-56
    • (2002) Am J Neuroradiol , vol.23 , pp. 151-156
    • Simon, E.M.1    Hevner, R.F.2    Pinter, J.D.3
  • 9
    • 0037168811 scopus 로고    scopus 로고
    • Middle interhemispheric variant of holoprosencephaly: A distinct cliniconeuroradiologic subtype
    • Lewis AJ, Simon EM, Barkovich AJ, et al. Middle interhemispheric variant of holoprosencephaly: A distinct cliniconeuroradiologic subtype. Neurology 2002;59:1860-65
    • (2002) Neurology , vol.59 , pp. 1860-1865
    • Lewis, A.J.1    Simon, E.M.2    Barkovich, A.J.3
  • 10
    • 0442278332 scopus 로고    scopus 로고
    • Early steps in the development of the forebrain
    • Wilson SW, Houart C. Early steps in the development of the forebrain. Dev Cell 2004;6:167-81
    • (2004) Dev Cell , vol.6 , pp. 167-181
    • Wilson, S.W.1    Houart, C.2
  • 11
    • 0035258973 scopus 로고    scopus 로고
    • Initial patterning of the central nervous system: How many organizers?
    • Stern CD. Initial patterning of the central nervous system: How many organizers? Nat Rev Neurosci 2001;2:92-98
    • (2001) Nat Rev Neurosci , vol.2 , pp. 92-98
    • Stern, C.D.1
  • 13
    • 0029059425 scopus 로고
    • Induction of epidermis and inhibition of neural fate by Bmp-4
    • Wilson PA, Hemmati-Brivanlou A. Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 1995;376:331-33
    • (1995) Nature , vol.376 , pp. 331-333
    • Wilson, P.A.1    Hemmati-Brivanlou, A.2
  • 14
    • 0030730266 scopus 로고    scopus 로고
    • Patterning of the chick forebrain anlage by the prechordal plate
    • Pera EM, Kessel M. Patterning of the chick forebrain anlage by the prechordal plate. Development 1997;124:4153-62
    • (1997) Development , vol.124 , pp. 4153-4162
    • Pera, E.M.1    Kessel, M.2
  • 15
    • 0031043536 scopus 로고    scopus 로고
    • A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
    • Li H, Tierney C, Wen L, et al. A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. Development 1997;124:603-15
    • (1997) Development , vol.124 , pp. 603-615
    • Li, H.1    Tierney, C.2    Wen, L.3
  • 16
    • 0036337358 scopus 로고    scopus 로고
    • Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development
    • Mathieu J, Barth A, Rosa FM, et al. Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. Development 2002;129:3055-65
    • (2002) Development , vol.129 , pp. 3055-3065
    • Mathieu, J.1    Barth, A.2    Rosa, F.M.3
  • 17
    • 33846100981 scopus 로고    scopus 로고
    • A dynamic fate map of the forebrain shows how vertebrate eyes form and explains two causes of cyclopia
    • England SJ, Blanchard GB, Mahadevan L, et al. A dynamic fate map of the forebrain shows how vertebrate eyes form and explains two causes of cyclopia. Development 2006;133:4613-17
    • (2006) Development , vol.133 , pp. 4613-4617
    • England, S.J.1    Blanchard, G.B.2    Mahadevan, L.3
  • 18
    • 0032545959 scopus 로고    scopus 로고
    • A small population of anterior cells patterns the forebrain during zebrafish gastrulation
    • Houart C, Westerfield M, Wilson SW. A small population of anterior cells patterns the forebrain during zebrafish gastrulation. Nature 1998;391:788-92
    • (1998) Nature , vol.391 , pp. 788-792
    • Houart, C.1    Westerfield, M.2    Wilson, S.W.3
  • 19
    • 0030796030 scopus 로고    scopus 로고
    • Inductive interactions direct early regionalization of the mouse forebrain
    • Shimamura K, Rubenstein JL. Inductive interactions direct early regionalization of the mouse forebrain. Development 1997;124:2709-18
    • (1997) Development , vol.124 , pp. 2709-2718
    • Shimamura, K.1    Rubenstein, J.L.2
  • 20
    • 0037130459 scopus 로고    scopus 로고
    • Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling
    • Houart C, Caneparo L, Heisenberg C, et al. Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron 2002;35;255-65
    • (2002) Neuron , vol.35 , pp. 255-265
    • Houart, C.1    Caneparo, L.2    Heisenberg, C.3
  • 21
    • 0033946448 scopus 로고    scopus 로고
    • Ace/Fgf8 is required for forebrain commissure formation and patterning of the telencephalon
    • Shanmugalingam S, Houart C, Picker A, et al. Ace/Fgf8 is required for forebrain commissure formation and patterning of the telencephalon. Development 2000;127:2549-61
    • (2000) Development , vol.127 , pp. 2549-2561
    • Shanmugalingam, S.1    Houart, C.2    Picker, A.3
  • 22
    • 0141502072 scopus 로고    scopus 로고
    • Unique and combinatorial functions of Fgf3 and Fgf8 during zebrafish forebrain development
    • Walshe J, Mason I. Unique and combinatorial functions of Fgf3 and Fgf8 during zebrafish forebrain development. Development 2003;130:4337-49
    • (2003) Development , vol.130 , pp. 4337-4349
    • Walshe, J.1    Mason, I.2
  • 23
    • 33748147910 scopus 로고    scopus 로고
    • FGF signalling generates ventral telencephalic cells independently of SHH
    • Gutin G, Fernandes M, Palazzolo L, et al. FGF signalling generates ventral telencephalic cells independently of SHH. Development 2006;133:2937-46
    • (2006) Development , vol.133 , pp. 2937-2946
    • Gutin, G.1    Fernandes, M.2    Palazzolo, L.3
  • 24
    • 0032957137 scopus 로고    scopus 로고
    • The specification of dorsal cell fates in the vertebrate central nervous system
    • Lee KJ, Jessell TM. The specification of dorsal cell fates in the vertebrate central nervous system. Annu Rev Neurosci 1999;22:261-94
    • (1999) Annu Rev Neurosci , vol.22 , pp. 261-294
    • Lee, K.J.1    Jessell, T.M.2
  • 25
    • 0030844354 scopus 로고    scopus 로고
    • Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development
    • Furuta Y, Piston DW, Hogan BL. Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 1997;124:2203-12
    • (1997) Development , vol.124 , pp. 2203-2212
    • Furuta, Y.1    Piston, D.W.2    Hogan, B.L.3
  • 26
    • 24344496641 scopus 로고    scopus 로고
    • Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation
    • Currle DS, Cheng X, Hsu CM, et al. Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation. Development 2005;132:3549-59
    • (2005) Development , vol.132 , pp. 3549-3559
    • Currle, D.S.1    Cheng, X.2    Hsu, C.M.3
  • 27
    • 0035842571 scopus 로고    scopus 로고
    • Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles
    • Crossley PH, Martinez S, Ohkubo Y, et al. Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles. Neuroscience 2001;108:183-206
    • (2001) Neuroscience , vol.108 , pp. 183-206
    • Crossley, P.H.1    Martinez, S.2    Ohkubo, Y.3
  • 28
    • 33747053414 scopus 로고    scopus 로고
    • Central roles of the roof plate in telencephalic development and holoprosencephaly
    • Cheng X, Hsu CM, Currle DS, et al. Central roles of the roof plate in telencephalic development and holoprosencephaly. J Neurosci 2006;26:7640-49
    • (2006) J Neurosci , vol.26 , pp. 7640-7649
    • Cheng, X.1    Hsu, C.M.2    Currle, D.S.3
  • 29
    • 33746273239 scopus 로고    scopus 로고
    • The roof plate regulates cerebellar cell-type specification and proliferation
    • Chizhikov VV, Lindgren AG, Currle DS, et al. The roof plate regulates cerebellar cell-type specification and proliferation. Development 2006;133:2793-804
    • (2006) Development , vol.133 , pp. 2793-2804
    • Chizhikov, V.V.1    Lindgren, A.G.2    Currle, D.S.3
  • 31
    • 0034981436 scopus 로고    scopus 로고
    • Genetic dissection of nodal function in patterning the mouse embryo
    • Lowe LA, Yamada S, Kuehn MR. Genetic dissection of nodal function in patterning the mouse embryo. Development 2001;128:1831-43
    • (2001) Development , vol.128 , pp. 1831-1843
    • Lowe, L.A.1    Yamada, S.2    Kuehn, M.R.3
  • 32
    • 0026433036 scopus 로고
    • The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system
    • Hatta K, Kimmel CB, Ho RK, et al. The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature 1991;350:339-41
    • (1991) Nature , vol.350 , pp. 339-341
    • Hatta, K.1    Kimmel, C.B.2    Ho, R.K.3
  • 33
    • 0029775625 scopus 로고    scopus 로고
    • Defective forebrain development in mice lacking gp330/megalin
    • Willnow TE, Hilpert J, Armstrong SA, et al. Defective forebrain development in mice lacking gp330/megalin. Proc Natl Acad Sci U S A 1996;93:8460-64
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8460-8464
    • Willnow, T.E.1    Hilpert, J.2    Armstrong, S.A.3
  • 34
    • 0037067722 scopus 로고    scopus 로고
    • Megalin functions as an endocytic sonic hedgehog receptor
    • McCarthy RA, Barth JL, Chintalapudi MR, et al. Megalin functions as an endocytic sonic hedgehog receptor. J Biol Chem 2002;277:25660-67
    • (2002) J Biol Chem , vol.277 , pp. 25660-25667
    • McCarthy, R.A.1    Barth, J.L.2    Chintalapudi, M.R.3
  • 35
    • 13944258550 scopus 로고    scopus 로고
    • LRP2/megalin is required for patterning of the ventral telencephalon
    • Spoelgen R, Hammes A, Anzenberger U, et al. LRP2/megalin is required for patterning of the ventral telencephalon. Development 2005;132:405-14
    • (2005) Development , vol.132 , pp. 405-414
    • Spoelgen, R.1    Hammes, A.2    Anzenberger, U.3
  • 36
    • 0029621784 scopus 로고
    • Longitudinal organization of the anterior neural plate and neural tube
    • Shimamura K, Hartigan DJ, Martinez S, et al. Longitudinal organization of the anterior neural plate and neural tube. Development 1995;121:3923-33
    • (1995) Development , vol.121 , pp. 3923-3933
    • Shimamura, K.1    Hartigan, D.J.2    Martinez, S.3
  • 37
    • 0030294408 scopus 로고    scopus 로고
    • Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
    • Roessler E, Belloni E, Gaudenz K, et al. Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat Genet 1996;14:357-60
    • (1996) Nat Genet , vol.14 , pp. 357-360
    • Roessler, E.1    Belloni, E.2    Gaudenz, K.3
  • 38
    • 0032732443 scopus 로고    scopus 로고
    • The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly
    • Nanni L, Ming JE, Bocian M, et al. The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly. Hum Mol Genet 1999;8:2479-88
    • (1999) Hum Mol Genet , vol.8 , pp. 2479-2488
    • Nanni, L.1    Ming, J.E.2    Bocian, M.3
  • 39
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
    • Chiang C, Litingtung Y, Lee E, et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 1996;383:407-13
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1    Litingtung, Y.2    Lee, E.3
  • 40
    • 0035512780 scopus 로고    scopus 로고
    • Mechanisms of cerebral cortical patterning in mice and humans
    • Monuki ES, Walsh CA. Mechanisms of cerebral cortical patterning in mice and humans. Nat Neurosci 2001;4 (Suppl):1199-206
    • (2001) Nat Neurosci , vol.4 , Issue.SUPPL. , pp. 1199-1206
    • Monuki, E.S.1    Walsh, C.A.2
  • 41
    • 33744528910 scopus 로고    scopus 로고
    • Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers
    • Storm EE, Garel S, Borello U, et al. Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development 2006;133:1831-44
    • (2006) Development , vol.133 , pp. 1831-1844
    • Storm, E.E.1    Garel, S.2    Borello, U.3
  • 42
    • 0033986616 scopus 로고    scopus 로고
    • Subcellular and developmental expression of alternatively spliced forms of fibroblast growth factor 14
    • Wang Q, McEwen DG, Ornitz DM. Subcellular and developmental expression of alternatively spliced forms of fibroblast growth factor 14. Mech Dev 2000;90:283-87
    • (2000) Mech Dev , vol.90 , pp. 283-287
    • Wang, Q.1    McEwen, D.G.2    Ornitz, D.M.3
  • 43
    • 0037452624 scopus 로고    scopus 로고
    • Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain
    • Storm EE, Rubenstein JL, Martin GR. Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain. Proc Natl Acad Sci U S A 2003;100:1757-62
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1757-1762
    • Storm, E.E.1    Rubenstein, J.L.2    Martin, G.R.3
  • 44
    • 0036848653 scopus 로고    scopus 로고
    • Chordin and noggin promote organizing centers of forebrain development in the mouse
    • Anderson RM, Lawrence AR, Stottmann RW, et al. Chordin and noggin promote organizing centers of forebrain development in the mouse. Development 2002;129:4975-87
    • (2002) Development , vol.129 , pp. 4975-4987
    • Anderson, R.M.1    Lawrence, A.R.2    Stottmann, R.W.3
  • 45
    • 0034628534 scopus 로고    scopus 로고
    • The organizer factors Chordin and Noggin are required for mouse forebrain development
    • Bachiller D, Klingensmith J, Kemp C, et al. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature 2000;403:658-61
    • (2000) Nature , vol.403 , pp. 658-661
    • Bachiller, D.1    Klingensmith, J.2    Kemp, C.3
  • 46
    • 1542267409 scopus 로고    scopus 로고
    • The mammalian twisted gastrulation gene functions in foregut and craniofacial development
    • Petryk A, Anderson RM, Jarcho MP, et al. The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol 2004;267:374-86
    • (2004) Dev Biol , vol.267 , pp. 374-386
    • Petryk, A.1    Anderson, R.M.2    Jarcho, M.P.3
  • 47
    • 0033514957 scopus 로고    scopus 로고
    • Ectopic bone morphogenetic proteins 5 and 4 in the chicken forebrain lead to cyclopia and holoprosencephaly
    • Golden JA, Bracilovic A, McFadden KA, et al. Ectopic bone morphogenetic proteins 5 and 4 in the chicken forebrain lead to cyclopia and holoprosencephaly. Proc Natl Acad Sci U S A 1999;96:2439-44
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2439-2444
    • Golden, J.A.1    Bracilovic, A.2    McFadden, K.A.3
  • 48
    • 0035311372 scopus 로고    scopus 로고
    • Holoprosencephaly due to mutations in ZIC2: Alanine tract expansion mutations may be caused by parental somatic recombination
    • Brown LY, Odent S, David V, et al. Holoprosencephaly due to mutations in ZIC2: Alanine tract expansion mutations may be caused by parental somatic recombination. Hum Mol Genet 2001;10:791-96
    • (2001) Hum Mol Genet , vol.10 , pp. 791-796
    • Brown, L.Y.1    Odent, S.2    David, V.3
  • 50
  • 51
    • 0032963512 scopus 로고    scopus 로고
    • Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin
    • Dale K, Sattar N, Heemskerk J, et al. Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin. Development 1999;126:397-408
    • (1999) Development , vol.126 , pp. 397-408
    • Dale, K.1    Sattar, N.2    Heemskerk, J.3
  • 52
    • 33751318012 scopus 로고    scopus 로고
    • Regional morphogenesis in the hypothalamus: A BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation
    • Manning L, Ohyama K, Saeger B, et al. Regional morphogenesis in the hypothalamus: A BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation. Dev Cell 2006;11:873-85
    • (2006) Dev Cell , vol.11 , pp. 873-885
    • Manning, L.1    Ohyama, K.2    Saeger, B.3
  • 53
    • 0037068832 scopus 로고    scopus 로고
    • BMP signaling is required locally to pattern the dorsal telencephalic midline
    • Hebert JM, Mishina Y, McConnell SK. BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron 2002;35:1029-41
    • (2002) Neuron , vol.35 , pp. 1029-1041
    • Hebert, J.M.1    Mishina, Y.2    McConnell, S.K.3
  • 54
    • 0035923738 scopus 로고    scopus 로고
    • Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway
    • Monuki ES, Porter FD, Walsh CA. Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway. Neuron 2001;32:591-604
    • (2001) Neuron , vol.32 , pp. 591-604
    • Monuki, E.S.1    Porter, F.D.2    Walsh, C.A.3
  • 55
    • 0035102275 scopus 로고    scopus 로고
    • The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity
    • Rohr KB, Barth KA, Varga ZM, et al. The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron 2001;29:341-51
    • (2001) Neuron , vol.29 , pp. 341-351
    • Rohr, K.B.1    Barth, K.A.2    Varga, Z.M.3
  • 56
    • 0032505052 scopus 로고    scopus 로고
    • Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling
    • Sampath K, Rubinstein AL, Cheng AM, et al. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature 1998;395:185-89
    • (1998) Nature , vol.395 , pp. 185-189
    • Sampath, K.1    Rubinstein, A.L.2    Cheng, A.M.3
  • 57
    • 0037348570 scopus 로고    scopus 로고
    • Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity
    • Take-uchi M, Clarke JD, Wilson SW. Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 2003;130:955-68
    • (2003) Development , vol.130 , pp. 955-968
    • Take-uchi, M.1    Clarke, J.D.2    Wilson, S.W.3
  • 58
    • 0033789065 scopus 로고    scopus 로고
    • Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS
    • Muller F, Albert S, Blader P, et al. Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development 2000;127:3889-97
    • (2000) Development , vol.127 , pp. 3889-3897
    • Muller, F.1    Albert, S.2    Blader, P.3
  • 59
    • 0037156473 scopus 로고    scopus 로고
    • Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles
    • Ohkubo Y, Chiang C, Rubenstein JL. Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles. Neuroscience 2002;111:1-17
    • (2002) Neuroscience , vol.111 , pp. 1-17
    • Ohkubo, Y.1    Chiang, C.2    Rubenstein, J.L.3
  • 60
    • 0042061387 scopus 로고    scopus 로고
    • A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon
    • Kuschel S, Ruther U, Theil T. A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon. Dev Biol 2003;260:484-95
    • (2003) Dev Biol , vol.260 , pp. 484-495
    • Kuschel, S.1    Ruther, U.2    Theil, T.3
  • 61
    • 0036848489 scopus 로고    scopus 로고
    • Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling
    • Rallu M, Machold R, Gaiano N, et al. Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development 2002;129:4963-74
    • (2002) Development , vol.129 , pp. 4963-4974
    • Rallu, M.1    Machold, R.2    Gaiano, N.3
  • 62
    • 0036434131 scopus 로고    scopus 로고
    • Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud
    • Aoto K, Nishimura T, Eto K, et al. Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud. Dev Biol 2002;251:320-32
    • (2002) Dev Biol , vol.251 , pp. 320-332
    • Aoto, K.1    Nishimura, T.2    Eto, K.3
  • 63
    • 0029617682 scopus 로고
    • Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
    • Oliver G, Mailhos A, Wehr R, et al. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 1995;121:4045-55
    • (1995) Development , vol.121 , pp. 4045-4055
    • Oliver, G.1    Mailhos, A.2    Wehr, R.3
  • 64
    • 0037314194 scopus 로고    scopus 로고
    • Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development
    • Lagutin OV, Zhu CC, Kobayashi D, et al. Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev 2003;17:368-79
    • (2003) Genes Dev , vol.17 , pp. 368-379
    • Lagutin, O.V.1    Zhu, C.C.2    Kobayashi, D.3
  • 65
    • 0036712099 scopus 로고    scopus 로고
    • Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye
    • Carl M, Loosli F, Wittbrodt J. Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye. Development 2002;129:4057-63
    • (2002) Development , vol.129 , pp. 4057-4063
    • Carl, M.1    Loosli, F.2    Wittbrodt, J.3
  • 66
    • 0033558871 scopus 로고    scopus 로고
    • Six3 overexpression initiates the formation of ectopic retina
    • Loosli F, Winkler S, Wittbrodt J. Six3 overexpression initiates the formation of ectopic retina. Genes Dev 1999;13:649-54
    • (1999) Genes Dev , vol.13 , pp. 649-654
    • Loosli, F.1    Winkler, S.2    Wittbrodt, J.3
  • 67
    • 0031691193 scopus 로고    scopus 로고
    • Overexpression of the forebrain-specific homeobox gene Six3 induces rostral forebrain enlargement in zebrafish
    • Kobayashi M, Toyama R, Takeda H, et al. Overexpression of the forebrain-specific homeobox gene Six3 induces rostral forebrain enlargement in zebrafish. Development 1998;125:2973-82
    • (1998) Development , vol.125 , pp. 2973-2982
    • Kobayashi, M.1    Toyama, R.2    Takeda, H.3
  • 68
    • 0348013158 scopus 로고    scopus 로고
    • Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain
    • Braun MM, Etheridge A, Bernard A, et al. Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain. Development 2003;130:5579-87
    • (2003) Development , vol.130 , pp. 5579-5587
    • Braun, M.M.1    Etheridge, A.2    Bernard, A.3
  • 69
    • 0034687424 scopus 로고    scopus 로고
    • Repressor activity of Headless/Tcf3 is essential for vertebrate head formation
    • Kim CH, Oda T, Itoh M, et al. Repressor activity of Headless/Tcf3 is essential for vertebrate head formation. Nature 2000;407:913-16
    • (2000) Nature , vol.407 , pp. 913-916
    • Kim, C.H.1    Oda, T.2    Itoh, M.3
  • 70
    • 0036337489 scopus 로고    scopus 로고
    • Early subdivisions in the neural plate define distinct competence for inductive signals
    • Kobayashi D, Kobayashi M, Matsumoto K, et al. Early subdivisions in the neural plate define distinct competence for inductive signals. Development 2002;129:83-93
    • (2002) Development , vol.129 , pp. 83-93
    • Kobayashi, D.1    Kobayashi, M.2    Matsumoto, K.3
  • 71
    • 10344234176 scopus 로고    scopus 로고
    • Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex
    • Shimogori T, Banuchi V, Ng HY, et al. Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex. Development 2004;131:5639-47
    • (2004) Development , vol.131 , pp. 5639-5647
    • Shimogori, T.1    Banuchi, V.2    Ng, H.Y.3
  • 72
    • 0034650621 scopus 로고    scopus 로고
    • Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)
    • Tole S, Ragsdale CW, Grove EA. Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol 2000:217:254-65
    • (2000) Dev Biol , vol.217 , pp. 254-265
    • Tole, S.1    Ragsdale, C.W.2    Grove, E.A.3
  • 73
    • 20444454292 scopus 로고    scopus 로고
    • Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis
    • Martynoga B, Morrison H, Price DJ, et al. Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis. Dev Biol 2005;283:113-27
    • (2005) Dev Biol , vol.283 , pp. 113-127
    • Martynoga, B.1    Morrison, H.2    Price, D.J.3
  • 74
    • 33748155402 scopus 로고    scopus 로고
    • Positive and negative regulations by FGF8 contribute to midbrain roof plate developmental plasticity
    • Alexandre P, Bachy I, Marcou M, et al. Positive and negative regulations by FGF8 contribute to midbrain roof plate developmental plasticity. Development 2006;133:2905-13
    • (2006) Development , vol.133 , pp. 2905-2913
    • Alexandre, P.1    Bachy, I.2    Marcou, M.3
  • 75
    • 0031694448 scopus 로고    scopus 로고
    • Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired
    • Brown SA, Warburton D, Brown LY, et al. Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired. Nat Genet 1998;20:180-83
    • (1998) Nat Genet , vol.20 , pp. 180-183
    • Brown, S.A.1    Warburton, D.2    Brown, L.Y.3
  • 76
    • 3342983260 scopus 로고    scopus 로고
    • Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation
    • Elms P, Scurry A, Davies J, et al. Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. Gene Expr Patterns 2004;4:505-11
    • (2004) Gene Expr Patterns , vol.4 , pp. 505-511
    • Elms, P.1    Scurry, A.2    Davies, J.3
  • 77
    • 0031568805 scopus 로고    scopus 로고
    • The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation
    • Nagai T, Aruga J, Takada S, et al. The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation. Dev Biol 1997;182:299-313
    • (1997) Dev Biol , vol.182 , pp. 299-313
    • Nagai, T.1    Aruga, J.2    Takada, S.3
  • 78
    • 17644402450 scopus 로고    scopus 로고
    • Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice
    • Shen J, Walsh CA. Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice. Mol Cell Biol 2005;25:3639-47
    • (2005) Mol Cell Biol , vol.25 , pp. 3639-3647
    • Shen, J.1    Walsh, C.A.2
  • 80
    • 16744368142 scopus 로고    scopus 로고
    • Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
    • Gripp KW, Wotton D, Edwards MC, et al. Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat Genet 2000;25:205-8
    • (2000) Nat Genet , vol.25 , pp. 205-208
    • Gripp, K.W.1    Wotton, D.2    Edwards, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.