The ω-atracotoxins: Selective blockers of insect M-LVA and HVA calcium channels

Biochemical Pharmacology

Volumn 74, Issue 4, 2007, Pages 623-638

  Chong, Youmie ^a   Hayes, Jessica L ^a   Sollod, Brianna ^b   Wen, Suping ^a   Wilson, David T ^e   Hains, Peter G ^c   Hodgson, Wayne C ^d   Broady, Kevin W ^a   King, Glenn F ^b   Nicholson, Graham M ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c SYDNEY EYE HOSPITAL   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

ACTX Ar1a; ACTX Hv1a; Atracotoxin; Atrax robustus; Insecticide; Voltage gated calcium channel

Indexed keywords

CALCIUM CHANNEL; NEUROTOXIN; OMEGA AGATOXIN IVA; OMEGA ATRACOTOXIN; OMEGA ATRACOTOXIN AR1A; OMEGA ATRACOTOXIN HV1A; PESTICIDE; POTASSIUM CHANNEL; SODIUM CHANNEL; SPIDER VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; ATRAX ROBUSTUS; BIOLOGICAL PEST CONTROL; CALCIUM CURRENT; CHANNEL GATING; COCKROACH; FLACCID PARALYSIS; INSECT; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; SPIDER; TOXICITY TESTING; VOLTAGE CLAMP;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CHICKENS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; FEMALE; GRYLLIDAE; LETHAL DOSE 50; MALE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUSCLE, SKELETAL; NEUROTOXINS; PERIPLANETA; RATS; RATS, SPRAGUE-DAWLEY; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; SPIDER VENOMS; SPIDERS; TOXICITY TESTS; VAS DEFERENS;

EID: 34447292303     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.05.017     Document Type: Article

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