Calcium- and calmodulin-dependent PMA-activation of the CD44 adhesion molecule

Cell Adhesion and Communication

Volumn 6, Issue 6, 1998, Pages 503-523

  Sionov, Ronit Vogt ^a   Naor, David ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Calmodulin; CD44; Hyaluronic acid; PMA

Indexed keywords

CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALMODULIN; CALMODULIN INHIBITOR; CELL ADHESION MOLECULE; CHLORPROMAZINE; CYCLOHEXIMIDE; HERMES ANTIGEN; HYALURONIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; POLYMYXIN B; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; QUERCETIN; SPHINGOSINE; STAUROSPORINE; TRIFLUOPERAZINE; TUMOR PROMOTER; VERAPAMIL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CELL SURFACE; GENE EXPRESSION; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0032433155     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069809010798     Document Type: Article

References (68)

1. Bartolazzi, A., Peach, R., Aruffo, A. and Stamenkovic, I. (1994). Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development. J. Exp. Med. 180, 53-66.
2. Bartolazzi, A., Noks, A., Aruffo, A., Spring, F. and Stamenkovic, I. (1996). Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan. J. Cell Biol. 132, 1199-1208.
3. Bennett, K.L., Modrell, B., Greenfield, B., Bartolazzi, A., Stamenkovic, I., Peach, R., Jackson, D.G., Spring, F. and Aruffo, A. (1995). Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons. J. Cell Biol. 131, 1623-1633.
4. Blumberg, P.M. (1988). Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture. Cancer Res. 48, 1-8.
5. Bostwick, J.R., Abbe, R. and Appel, S.H. (1993). Modulation of acetytcholine release in rat hippocampus by aminoalcohols and Bay K8644. Brain Res. 629, 79-87.
6. Bourguignon, L.Y., Lokeshwar, V.B., Chen, X. and Kertick, W.G. (1993). Hyaluronic acid-induced lymphocyte signal transduction and HA receptor (GP85/CD44)-cytoskeleton interaction. J. Immunol. 151, 6634-6644.
7. Brown, T.A., Bouchard, T., Wayner, St.J.E. and Carter, W.G. (1991). Human keratinocytes express a new CD44 core protein (CD44E) as a heparan sulfate intrinsic membrane proteoglycan with additional exons. J. Cell Biol. 113, 207-221.
8. Cao, Y.-Z., Reddy, C. and Mastro, A.M. (1990). Evidence for protein kinase C independent activation of phospholipase D by phorbol esters in lymphocytes. Biochem Biophys. Res. Comm. 177, 955-962.
9. Cato, A.C. and Wade, E. (1996). Molecular mechanisms of anti-inflammatory action of glucocorticoids. Bioassays 18, 371-378.
10. Coll, M.J., Serratosa, J., Bachs, O., Gahmberg, C.G. and Enrich, C. (1986). Calmodulin may decrease cell surface sialic acid and be involved in the expression of fibronectin during liver regeneration. FEBS Letter 208, 418-422.
11. Conquer, J.A., Kandel, R.A. and Cruz, T.F. (1992). Interleukin-1 and phorbol 12-myristate 13-acetate induce collagenase and PGE2 production through a PKC-independent mechanisms in chondrocytes. Biochim. Biophys. Acta 1134, 1-6.
12. Cooper, D.L. and Dougherty, G.J. (1995). To metastasize or not? Selection of CD44 splice sites. Nat. Med. 1, 635-637.
13. de Belder, A.N. and Wik, K.O. (1975). Preparation and properties of fluorescein-labelled hyaluronate. Carbohydr. Res. 44, 251-257.
14. Eisenberger, M.A. and Reyno, L.M. (1994). Suramin. Cancer Treat. Rev. 20, 259-273.
15. Fruman, D.A., Klee, C.B., Bierer, B.E. and Burakoff, S.J. (1992). Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A. Proc. Natl. Acad. Sci. USA 89, 3686-3690.
16. Galluzzo, E., Albi, N., Fiorucci, S., Merigiola, C., Ruggeri, L., Tosti, A., Grossi, C.E. and Velardi, A. (1995). Involvement of CD44 variant isoforms in hyaluronate adhesion by human activated T cells. Eur. J. Immunol. 25, 2932-2939.
17. Gnegy, M.E. (1995). Calmodulin: Effects of cell stimuli and drugs on cellular activation. Prog. Drug Res. 45, 33-65.
18. Günthert, U. (1996). CD44 in malignant disorders. Curr. Top. Microbiol. Immunol. 213, 217-285.
19. Hunakova, L., Sedlak, J., Klobusicka, M., Sulikova, M. and Chorvath, B. (1995). Phorbol ester (TPA)-induced differential modulation of cell surface antigen in human pluripotential leukemia (K-562) cell line: effects of protein kinase inhibitors with broad- and PKC selective inhibitory activity. Neoplasma 42, 249-253.
20. Jackson, D.G., Bell, J.I., Dickinson, R., Timans, J., Shields, J. and Whittle, N. (1995). Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the V3 exon. J. Cell Biol. 128, 673-685.
21. Katoh, S., Zheng, Z., Oritani, K., Shimozato, T. and Kincade, P.W. (1995). Glycosylation of CD44 negatively regulates its recognition of hyaluronan. J. Exp. Med. 182, 419-429.
22. 2+/ calmodulin and protein kinase C regulation of serotonin transport in human K562 lymphocytes. Cell. Immunol. 172, 269-274.
23. Knudson, C.B. and Knudson, W. (1993). Hyaluronan-binding proteins in development, tissue homeostasis, and disease. FASEB J. 7, 1233-1241.
24. Knudson, W. (1996). Tumor-associated hyaluronan. Providing an extracellular matrix that facilitates invasion. Am. J. Pathol. 148, 1721-1726.
25. Laurent, T.C., Laurent, U.B. and Fraser, J.R. (1995). Functions of hyaluronan. Ann. Rheum. Dis. 54, 429-432.
26. Lesley, J., He, Q., Miyake, K., Hamann, A., Hyman, R. and Kincade, P.W. (1992). Requirements for hyaluronic acid binding by CD44: A role for the cytoplasmic domain and activation by antibody. J. Exp. Med. 175, 257-266.
27. Lesley, J., Hyman, R. and Kincade, P.W. (1993a). CD44 and its interaction with the extracellular matrix. Adv. Immunol. 54, 271-335.
28. Lesley, J., Kincade, P.W. and Hyman, R. (1993b). Antibody-induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody. Eur. J. Immunol. 23, 1902-1909.
29. Lesley, J., English, N., Perschl, A., Gregoroff, J. and Hyman, R. (1995). Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J. Exp. Med. 182, 431-437.
30. Lewis, R.S. and Cahalan, M.D. (1995). Potassium and calcium channels in lymphocytes. Annu. Rev. Immunol. 13, 623-653.
31. Liao, H.-X., Levesque, M.C., Patton, K., Bergamo, B., Jones, D., Moody, M.A., Telen, M.J. and Haynes, B.F. (1993). Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies. J. Immunol. 151, 6490-6499.
32. Liao, H.-X., Lee, D.M., Levesque, M.C. and Haynes, B.F. (1995). N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding. J. Immunol. 155, 3938-3945.
33. Liu, D., Zhang, D., Mori, H. and Sy, M.-S. (1996). Binding of CD44 to hyaluronic acid can be induced by multiple signals and requires the CD44 cytoplasmic domain. Cell. Immunol. 174, 73-83.
34. Lokeshwar, V.B., Fregien, N. and Bourguignon, L.Y. (1994). Ankyrin-binding of CD44 (GP85) is required for the expression of hyaluronic acid-mediated adhesion function. J. Cell Biol. 126, 1099-1109.
35. 2+ in monolayers and suspensions of various types of animal cells. J. Cell Biol. 105, 2145-2155.
36. McKnight, G.S. (1991). Cyclic AMP second messenger systems. Curr. Opin. Cell Biol. 3, 213-217.
37. Mtairag, E.M., Abdelghaffar, H., Douhet, C. and Labro, M.T. (1995). Role of extracellular calcium in in vitro uptake and intraphagocytic location of macrolides. Antimicrob. Agents Chemother. 39, 1676-1682.
38. Murakami, S., Miyake, K., June, C.H., Kincade, P.W. and Hodes, R.J. (1990). IL-5 induces a pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate. J. Immunol. 145, 3618-3627.
39. Murakami, S., Shimabukuro, Y., Miki, Y., Saho, T., Hino, E., Kasai, D., Nozaki, T., Kusumoto, Y. and Okada, H. (1994). Inducible binding of human lymphocytes to hyaluronate via CD44 does not require cytoskeleton association but does require new protein synthesis. J. Immunol. 152, 467-477.
40. Naor, D., Vogt Sionov, R. and Ish-Shalom, D. (1997). CD44: Structure, function and association with the malignant process. Adv. Cancer Res. 71, 241-319.
41. Opie, L.H. (1996). Calcium channel antagonists in the treatment of coronary artery disease: Fundamental pharmacological properties relevant to clinical use. Prog. Cardiovascular Dis. 38, 273-290.
42. Peach, R.J., Hollenbaugh, D., Stamenkovic, I. and Aruffo, A. (1993). Identification of hyaluronic acid binding sites in the extracellular domain of CD44. J. Cell Biol. 122, 257-264.
43. Peck, D. and Isacke, C.M. (1996). CD44 phosphorylation regulates melanoma cell and fibroblast migration on, but not attachment to, a hyaluronan substratum. Curr. Biol. 6, 884-890.
44. Perschl, A., Lesley, J., English, N., Trowbridge, I. and Hyman, R. (1995). Role of CD44 cytoplasmic domain in hyaluronan binding. Eur. J. Immunol. 25, 495-501.
45. Planelles, D., Hernandez-Godoy, J. and Gonzalez-Molina, A. (1992). Differential effects of the calcium ionophore A23187 and the phorbol ester PMA on lymphocyte proliferation. Agents Actions 35, 238-244.
46. Puré, E., Camp, R.L., Peritt, D., Panettieri, R.A. Jr., Lazaar, A.L. and Nayak, S. (1995). Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain. J. Exp. Med. 181, 55-62.
47. Rochman, M., Moll, J., Herrlich, P., Wallach, B., Nedvetzki, S., Vogt Sionov, R., Golan, I., Ish-Shalom, D. and Naor, D. (Submitted). Cell surface CD44 activation is associated with the synergistic effect of phorbol ester-dependent signaling and receptor deglycosylation.
48. Rosen, L.B., Ginty, D.D. and Greenberg, M.E. (1995). Calcium regulation of gene expression. Adv. Second Messenger Phosphoprotein Res. 30, 225-253.
49. Ruggiero, R.A., Bastuobad, O.D., Bonfil, R.D., Meiss, R.P. and Pasqualini, C.D. (1985). "Concomitant immunity" in murine tumours of non-detectable immunogenicity. Br. J. Cancer 51, 37-48.
50. Screaton, G.R., Bell, M.V., Jackson, D.G., Cornelis, F.B., Gerth, U. and Bell, J.I. (1992). Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. USA 89, 12160-12164.
51. Seger, R. and Krebs, E.G. (1995). The MAPK signaling cascade. FASEB J. 9, 726-735.
52. Sherman, L., Sleeman, J., Herrlich, P. and Ponta, H. (1994). Hyaluronate receptors: key players in growth, differentiation, migration, and tumor progression. Curr. Opin. Cell. Biol. 6, 726-733.
53. Sleeman, J.P., Arming, S., Moll, J.F., Hekele, A., Rudy, W., Sherman, L.S., Kreil, G., Ponta, H. and Herrlich, P. (1996). Hyaluronate-independent metastatic behaviour of CD44 variant-expressing pancreatic carcinoma cells. Cancer Res. 56, 3134-3141.
54. 2+ signals in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Pflugers Arch. 428, 275-282.
55. Stamenkovic, I., Aruffo, A., Amiot, M. and Seed, B. (1991). The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate bearing cells. EMBO J. 10, 343-348.
56. Takahashi, K., Stamenkovic, I., Cutler, M., Dasgupta, A. and Tanabe, K.K. (1996). Keratan sulfate modification of CD44 modulates adhesion to hyaluronate. J. Biol. Chem. 271, 9490-9496.
57. Tamir, A., Granot, Y. and Isakov, N. (1996). Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase. J. Immunol. 157, 1514-1522.
58. Thomas, L., Byers, H.R., Vink, J. and Stamenkovic, I. (1992). CD44H regulates tumor cell migration on hyaluronate-coated substrate. J. Cell Biol. 118, 971-977.
59. Tölg, C., Hofmann, M., Herrlich, P. and Ponta, H. (1993). Splicing choice from ten variant exons establishes CD44 variability. Nucleic Acids Res. 21, 1225-1229.
60. Tsien, R.Y. and Poenie, M. (1986). Fluorescence ratio imaging: a new window into intracellular ionic signaling. TIBS 11, 450-455.
61. Tsukita, S., Oishi, K., Sato, N., Sagara, J., Kawai, A. and Tsukita, S. (1994). ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J. Cell Biol. 126, 391-401.
62. Uff, C.R., Neame, S.J. and Isacke, C.M. (1995). Hyaluronan binding by CD44 is regulated by a phosphorylation-independent mechanism. Eur. J. Immunol. 25, 1883-1887.
63. van Muijen, G.N., Danen, E.H., Veerkamp, J.H., Ruiter, D.J., Lesley, J. and van den Heuvel, L.P. (1995). Glycoconjugate profile and CD44 expression on human melanoma cell lines with different metastatic capacity. Int. J. Cancer 61, 241-248.
64. Vogel, H.J. and Zhang, M. (1995). Protein engineering and NMR studies of calmodulin. Mol. Cell. Biochem. 149/150, 3-15.
65. + lymphoma cells in lymphoid organs. Int. J. Cancer 71, 462-469.
66. 2+ and the regulation of early response gene expression in HL-60 myeloid leukemia cells. J. Biol. Chem. 268, 16596-16601.
67. Zahalka, M.A., Okon, E., Gosslar, U., Holzmann, B. and Naor, D. (1995). Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent. J. Immunol. 154, 5345-5355.
68. Zhang, L., Underhill, C.B. and Chen, L. (1995). Hyaluronan on the surface of tumor cells is correlated with metastatic behavior. Cancer Res. 55, 428-433.