Conceptualising the imapct of genetic testing on cancer disparities in the USA

International Journal of Healthcare Technology and Management

Volumn 8, Issue 5, 2007, Pages 536-548

  Ponce, Ninez A ^a   Afable Munsuz, Aimee ^b   Nordyke, Robert J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acculturation; Cancer risk; Genetic testing; Racial ethic disparities

Indexed keywords

ARTICLE; AWARENESS; CANCER GENETICS; CANCER RISK; CONSUMER; CULTURAL FACTOR; GENE MUTATION; GENETIC DISORDER; GENETIC SCREENING; GERM LINE; HEALTH CARE QUALITY; HEALTH CARE SYSTEM; HEALTH INSURANCE; HUMAN; IMMIGRANT; MALIGNANT NEOPLASTIC DISEASE; PREDICTION; RACE; UNITED STATES;

EID: 34347404666     PISSN: 13682156     EISSN: None     Source Type: Journal    
DOI: 10.1504/IJHTM.2007.013522     Document Type: Article

References (80)

1. Armstrong, K., Micco, E., Carney, A., Stopfer, J. and Putt, M. (2005) 'Racial differences in the use of BRCA1/2 testing among women with a family history of breast or ovarian cancer', Journal of the American Medical Association, Vol. 293, No. 14, pp. 1729-1736.
2. Bach, P. (2005) 'Racial disparities and site of care', Ethnicity & Disease, Vol. 15, No. 2 (Suppl 2), pp. S31-33.
3. Bach, P.B., Pham, H.H., Schrag, D., Tate, R.C. and Hargraves, J.L. (2004) 'Primary care physicians who treat blacks and whites', New England Journal of Medicine, Vol. 6, pp. 575-584.
4. Balsa, A., McGuire, T. and Meredith, L. (2005) 'Testing for statistical discrimination in health care', Health Services Research, Vol. 40, No. 1, pp. 227-252.
5. Balsa, A.I. and McGuire, T.G. (2003) 'Prejudice, clinical uncertainty and stereotyping as sources of health disparities', J Health Econ., Vol. 22, No. 1, pp. 89-116.
6. Bamshad, M.J., Wooding, S., Watkins, W.S., Ostler, C.T., Batzer, M.A. and Jorde, L.B. (2003) 'Human population genetic structure and inference of group membership', American Journal of Human Genetics, Vol. 72, No. 3, pp. 578-599.
7. Berry, JW. (1980a) 'Acculturation as varieties of adaptation', in A.M. Padilla (Ed) Acculturation, Theory, Models, and Some New Findings, Boulder, CO: Westview Press.
8. Berry, JW. (1980b) 'The role of cultural awareness and ethnic loyalty in acculturation', in A.M. Padilla (Ed) Acculturation, Theory, Models, and Some New Findings, Boulder, CO: Westview Press.
9. Bishaw, A and Iceland, J. (2003) Poverty: 1999, U.S.C. Bureau.
10. Breen, N., Wagener, D.K., Brown, M.L., Davis, W.W. and Ballard-Barbash, R. (2001) 'Progress in cancer screening over a decade: results of cancer screening from the 1987, 1992, and 1998 National Health Interview Surveys', Journal of the American Cancer Institute, Vol. 93, No. 22, pp. 1704-1713.
11. Brown, E.R., Ponce, N., Rice, T. and Lavarreda, S.A. (2003) 'The state of health insurance in California: findings from the 2001 California Health Interview Survey', UCLA Center for Health Policy Research.
12. Bruner, D.W., Jones, M., Buchanan, D. and Russo, J. (2006) 'Reducing cancer disparities for minorities: a multidisciplinary research agenda to improve patient access to health systems, clinical trials, and effective cancer therapy', Journal of Clinical Oncology, Vol. 24, No. 14, pp. 2209-2215.
13. Catz, D.S., Green, N.S., Tobin, J.N., Lloyd-Puryear, M.A., Kyler, P., Umemoto, A., Cernoch, J., Brown, R. and Wolman, F. (2005) 'Attitudes about genetics in underserved, culturally diverse populations', Community Genetics, Vol. 8, No. 3, pp. 161-72.
14. Chen, J.Y., Diamant, A.L., Kagawa-Singer, M., Pourat, N. and Wold, C. (2004) 'Disaggregating data on Asian and Pacific Islander women to assess cancer screening', American Journal of Preventive Medicine, Vol. 27, No. 2, pp. 139-145.
15. Clark, T., Sleath, B. and Rubin, R.H. (2004) 'Influence of ethnicity and language concordance on physician-patient agreement about recommended changes in patient health behavior', Patient Education and Counseling, Vol. 53, No. 1, pp. 87-93.
16. Crul, M. and Vermeulen, H. (2003) 'The second generation in Europe. Introduction', International Migration Review, Vol. 37, No. 4, pp. 965-986.
17. De Alba, I., Sweningson, J.M., Chandy, C. and Hubbell, F.A. (2004) 'Impact of English language proficiency on receipt of pap smears among Hispanics', Journal of General Internal Medicine, Vol. 19, No. 9, pp. 967-970.
18. Doksum, T., Bernhardt, B.A. and Bernhardt, H.N.A. (2003) 'Does knowledge about the genetics of breast cancer differ between nongeneticist physicians who do or do not discuss or order BRCA testing?', Genetics in Medicine, Vol. 5, No. 2, pp. 99-105.
19. Dulai, G.S., Farmer, M.M., Ganz, P.A., Bernaards, A., Qi, K., Dietrich, A.J., Bastani, R., Belman, M.J. and Kahn, K.L. (2004) 'Primary care provider perceptions of barriers to and facilitators of colorectal cancer screening in a managed care setting', Cancer, Vol. 100, No. 9, pp. 1843-1852.
20. Etzioni, D.A., Ponce, N.A., Babey, S.H., Spencer, B.A., Brown, E.R., Ko, C.Y., Chawla, N., Breen, N. and Klabunde, C.N. (2004) 'A population-based study of colorectal cancer test use: results from the 2001 California Health Interview Survey', Cancer, Vol. 101, No. 11, pp. 2523-2532.
21. Fernandez, A., Schillinger, D., Grumbach, K., Rosenthal, A., Stewart, A.L., Wang, F. and Perez-Stable, E.J. (2004) 'Physician language ability and cultural competence. An exploratory study of communication with Spanish-speaking patients', Journal of General Internal Medicine, Vol. 19, No. 2, pp. 167-174.
22. Goel, M.S., Wee, C.C., McCarthy, E.P., Davis, R.B., Ngo-Metzger, Q. and Phillips, R.S. (2003) 'Racial and ethnic disparities in cancer screening: the importance of foreign birth as a barrier to care', Journal of General Internal Medicine, Vol. 18, No. 12, pp. 1028-1035.
23. Goodman, M.J., Ogdie, A., Kanamori, M.J., Canar, J. and O'Malley, A.S. (2006) 'Barriers and facilitators of colorectal cancer screening among Mid-Atlantic Latinos: focus group findings', Ethnicity & Disease, Vol. 16, No. 1, pp. 255-261.
24. Gramling, R., Nash, J., Siren, K. and Culpepper, L. (2003) 'Predictive genetics in primary care: expectations for the motivational impact of genetic testing affects the importance family physicians place on screening for familial cancer risk', Genetics in Medicine, Vol. 5, No. 3, pp. 172-175.
25. Halbert, C.H., Kessler, L.J. and Mitchell, E. (2005) 'Genetic testing for inherited breast cancer risk in African Americans', Cancer Investigation, Vol. 23, No. 4, pp. 285-295.
26. Hall, J.M., Lee, M.K., Newman, B., Morrow, J.E., Anderson, L.A., Huey, B. and King, M.C. (1990) 'Linkage of early-onset familial breast cancer to chromosome 17q21', Science, Vol. 250, pp. 1684-1689.
27. Hall, M.J. and Olopade, O.I. (2006) 'Disparities in genetic testing: thinking outside the BRCA box', Journal of Clinical Oncology, Vol. 24, No. 14, pp. 2197-2203.
28. Harlan, L.C., Greene, A.L., Clegg, L.X., Mooney, M., Stevens, J.L. and Brown, M.L. (2005) 'Insurance status and the use of guideline therapy in the treatment of selected cancers', Journal of Clinical Oncology, Vol. 23, No. 36, pp. 9079-9088.
29. Hobbs, F., Hobbs, S.N. and Stoops, N. (2002) 'Demographic trends in the 20th century', U.C. Bureau.
30. Honda, K. (2003) 'Who gets the information about genetic testing for cancer risk? The role of race/ethnicity, immigration status, and primary care clinicians', Clinical Genetics, Vol. 64, No. 2, pp. 131-136.
31. Hunt, L.M., Schneider, S. and Comer, B. (2004). 'Should 'acculturation' be a variable in health research? A critical review of research on US Hispanics', Social Science & Medicine, Vol. 59, No. 5, pp. 973-986.
32. Jones, N.A. and Smith, A. (2001) 'The two or more races population: 2000', U.C. Bureau.
33. Kagawa-Singer, M. and Pourat, N. (2000) 'Asian American and Pacific Islander breast and cervical carcinoma screening rates and healthy people 2000 objectives', Cancer, Vol. 89, No. 3, pp. 696-705.
34. Kaplan, C.P., Haas, J.S., Perez-Stable, E.J., Gregorich, S.E., Somkin, C., Des Jarlais, G. and Kerlikowske, K. (2006) 'Breast cancer risk reduction options: awareness, discussion, and use among women from four ethnic groups', Cancer Epidemiology, Biomarkers & Prevention, Vol. 15, No. 1, pp. 162-166.
35. Klabunde, C.N., Vernon, S.W., Nadel, M.R., Breen, N., Seeff, L.C. and Brown, M.L. (2005) 'Barriers to colorectal cancer screening: a comparison of reports from primary care physicians and average-risk adults', Medical Care, Vol. 43, No. 9, pp. 939-944.
36. Ku, L. and Matani, S. (2001) 'Left out: immigrants' access to health care and insurance', Health Aff (Millwood), Vol. 20, No. 1, pp. 247-256.
37. Lara, M., Gamboa, C., Kahramanian, M.I., Morales, L.S. and Bautista, D.E. (2005) 'Acculturation and Latino health in the United States: a review of the literature and its sociopolitical context', Annual Review of Public Health, Vol. 26, pp. 367-397.
38. Lee, S.S. (2003) 'Race, distributive justice and the promise of pharmacogenomics: ethnical considerations', American Journal of Pharmacogenomics, Vol. 3, No. 6, pp. 385-392.
39. Lee, S.S. (2005) 'Racializing drug design: implications of pharmacogenomics for health disparities', American Journal of Public Health, Vol. 95, No. 12, pp. 2133-2138.
40. Liang, S.Y., Phillips, K.A., Nagamine, M., Ladabaum, U. and. Haas, J.S. (2006) 'Trends in adherence to colorectal cancer screening guidelines', Preventing Chronic Disease, in press, accepted 2/17/06.
41. Lindblom, A., Tannergard, P., Werelius, B. and Nordenskjold, M. (1993) 'Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer', Nature Genetics, Vol. 5, pp. 279-282.
42. Malone, N., Baluja, K.R., Constanzo, J.M. and Davis, C.J. (2003) 'The foreign-born population: 2000', Census 2000 Brief C2KBR-34, US Census Bureau, Washington, DC.
43. Manson, A. (1988) 'Language concordance as a determinant of patient compliance and emergency room use in patients with asthma', Medical Care, Vol. 26, No. 12, pp. 1119-1128.
44. Mays, V., Ponce, N., Washington, D. and Cochran, S. (2003) 'Classification of race and ethnicity: implications for public health', Annual Review of Public Health, Vol. 24, pp. 83-110.
45. Meissner, H.I., Breen, N., Klabunde, C.N. and Vernon, S.W. (2006) 'Patterns of colorectal cancer screening uptake among men and women in the United States', Cancer Epidemiology, Biomarkers & Prevention, Vol. 15, No. 2, pp. 389-394.
46. Nagamine, M., Liang, S.Y., Phillips, K.A. and Haas, J.S. (2006) 'Association of income and sociodemographic characteristics on colorectal cancer screening behaviors', forthcoming paper.
47. Nanda, R., Schumm, L.P., Cummings, S., Fackenthal, J.D., Sveen, L., Ademuyiwa, F., Cobleigh, M., Esserman, L., Lindor, N.M., Neuhausen, S.L. and Olopade, O.I. (2005) 'Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry', Journal of the American Medical Association, Vol. 294, No. 15, pp. 1925-1933.
48. Nicolaides, N.C., Papadopoulos, N. and Liu, B. (1994) 'Mutations of two PMS homologues in hereditary nonpolyposis colon cancer', Nature, Vol. 371, pp. 75-80.
49. Nystrom-Lahti, M., Parsons, R. and Sistonen, P. (1994) 'Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage', American Journal of Human Genetics Vol. 55, pp. 659-665.
50. O'Malley, A.S., Beaton, E., Yabroff, K.R., Abramson, R. and Mandelblatt, J. (2004) 'Patient and provider barriers to colorectal cancer screening in the primary care safety-net', Preventive Medicine, Vol. 39, No. 1, pp. 56-63.
51. Patel, D.A., Knowles, A., Schwartz, A.G. and Schwartz, K. (2005) 'Evaluation of African-American and white racial classification in a surveillance, epidemiology, and end results cancer registry', Ethnicity & Disease, Vol. 15, No. 4, pp. 713-719.
52. Peek, M.E. and Han, J.H. (2004) 'Disparities in screening mammography. Current status, interventions and implications', Journal of General Internal Medicine, Vol. 19, No. 2, pp. 184-194.
53. Peltomäki, P., Aaltonen, L.A. and Sistonen, P. (1993) 'Genetic mapping of a locus predisposing to human colorectal cancer', Science, Vol. 260, pp. 810-812.
54. Peters, N., Rose, A. and Armstrong, K. (2004) 'The association between race and attitudes about predictive genetic testing', Cancer Epidemiology, Biomarkers & Prevention, Vol. 13, No. 3, pp. 361-365.
55. Pollock, H and Kronebusch, K. (2004) 'Health insurance and vulnerable populations', in C. G. McLaughlin (Ed) Health Policy and the Uninsured, Washington, DC: The Urban Institute Press.
56. Ponce, N., Nordyke, R.J. and Hirota, S. (2005a) 'Uninsured working immigrants: a view from a California county', Journal of Immigrant Health, Vol. 7, No. 1, pp. 45-53.
57. Ponce, N.A., Huh, S. and Bastani, R. (2005b) 'Do HMO market level factors lead to racial/ethnic disparities in colorectal cancer screening? A comparison between high-risk Asian and Pacific Islander Americans and high-risk whites', Medical Care, Vol. 43, No. 11, pp. 1101-1108.
58. Portes, A. and Schauffier, R. (1996) 'Language and the second generation: bilingualism yesterday and today', in A. Portes (Ed) The New Second Generation, New York, NY: Russell Sage Foundation.
59. Rice, T. (2003) 'The impact of cost containment efforts on racial and ethnic disparities in healthcare: a conceptualization', in B.D. Smedley, A.Y. Stith and A.R. Nelson (Eds) Unequal Treatment: Confronting Racial and Ethnic Disparities in Healthcare, Institute of Medicine.
60. Rimer, B.K., Briss, P.A., Zeller, P.K., Chan, E.C. and Woolf, S.H. (2004) 'Informed decision making: what is its role in cancer screening?', Cancer, Vol. 101, No. 5 (Suppl), pp. 1214-1228.
61. Saha, S., Arbelaez, J.J. and Cooper, L.A. (2003) 'Patient-physician relationships and racial disparities in the quality of health care', American Journal of Public Health, Vol. 93, No. 10, pp. 1713-1719.
62. Salsberg, E.S. and Forte, G.J. (2002) 'Trends in the physician workforce, 1980-2000', Health Affairs, Vol. 21, No. 5, pp. 165-173.
63. Sankar, P., Cho, M.K., Condit, C.M., Hunt, L.M., Koenig, B., Marshall, P., Lee, S.S. and Spicer, P. (2004) 'Genetic research and health disparities', Journal of the American Medical Association, Vol. 291, No. 24, pp. 2985-2989.
64. Shavers, V.L. and Brown, M.L. (2002) 'Racial and ethnic disparities in the receipt of cancer treatment', Journal of the National Cancer Institute, Vol. 94, No. 5, pp. 334-357.
65. Smedley, A. and Smedley, B.D. (2006) 'Race as biology is fiction, racism as a social problem is real: anthropological and historical perspectives on the social construction of race', American Psychologist, Vol. 61, No. 2, pp. 179-180.
66. Smedley, B.D., Stith, A.Y. and Nelson, A.R. (2003) 'Unequal treatment: confronting racial and ethnic disparities in health care', Institute of Medicine, National Academies Press.
67. Stehr-Green, P., Bettles, J. and Robertson, L.D. (2002) 'Effect of racial/ethnic misclassification of American Indians and Alaskan Natives on Washington State death certificates, 1989-1997', American Journal of Public Health, Vol. 92, No. 3, pp. 443-444.
68. Swan, J., Breen, N., Burhansstipanov, L., Satter, D.E., Davis, W.W., McNeel, T. and Snipp, C.M. (2006) 'Cancer screening and risk factor rates among American Indians', American Journal of Public Health, Vol. 96, No. 2, pp. 340-350.
69. Swan, J., Breen, N., Coates, R.J., Rimer, B.K. and Lee, N.C. (2003) 'Progress in cancer screening practices in the United States: results from the 2000 National Health Interview Survey', Cancer, Vol. 97, No. 6, pp. 1528-1540.
70. Szapocznik, J. and Kurtines, W. (1980) 'Acculturation, biculturalism and adjustment among Cuban-Americans', in A.M. Padilla (Ed) Acculturation, Theory, Models, and some New Findings, Boulder, CO: Westview Press.
71. Taylor, M.L. and Anderson, R. (2002) 'Colorectal cancer screening: physician attitudes and practices', Wisconsin Medical Journal, Vol. 101, No. 5, pp. 39-43.
72. Thompson, H.S., Valdimarsdottir, H.B., Jandorf, L. and Redd, W. (2003) 'Perceived disadvantages and concerns about abuses of genetic testing for cancer risk: differences across African American, Latina and Caucasian women', Patient Education and Counseling, Vol. 51, No. 3, pp. 217-227.
73. Vadaparampil, S.T., Wideroff, L., Breen, N. and Trapido, E. (2006) 'The impact of acculturation on awareness of genetic testing for increased cancer risk among Hispanics in the year 2000 National Health Interview Survey', Cancer Epidemiology, Biomarkers & Prevention, Vol. 15, No. 4, pp. 618-623.
74. Wee, C.C., McCarthy, E.P. and Phillips, R.S. (2005) 'Factors associated with colon cancer screening: the role of patient factors and physician counseling', Preventive Medicine, Vol. 41, No. 1, pp. 23-29.
75. Wideroff, L., Freedman, AX, Olson, L., Klabunde, C.N., Davis, W., Srinath, K.P., Croyle, R.T. and Ballard-Barbash, R. (2003) 'Physician use of genetic testing for cancer susceptibility: results of a national survey', Cancer Epidemiology, Biomarkers & Prevention, Vol. 12, No. 4, pp. 295-303.
76. Wideroff, L., Vadaparampil, S.T., Breen, N., Croyle, R.T. and Freedman, A.N. (2003) 'Awareness of genetic testing for increased cancer risk in the year 2000 National Health Interview Survey', Community Genetics, Vol. 6, No. 3, pp. 147-156.
77. Wiltshire, J., Cronin, K., Sarto, G.E. and Brown, R. (2006) 'Self-advocacy during the medical encounter: use of health information and racial/ethnic differences', Medical Care, Vol. 44, No. 2, pp. 100-109.
78. Wong, S.T., Gildengorin, G., Nguyen, T. and Mock, J. (2005) 'Disparities in colorectal cancer screening rates among Asian Americans and non-Latino whites', Cancer, Vol. 104, No. 12 (Suppl), pp. 2940-2947.
79. Wooster, R., Neuhausen, S.L. and Mangon, J. (1994) 'Location of a breast cancer susceptibility gene BRCA 2, to chromosome 13q12-13', Science, Vol. 265, pp. 2088-2090.
80. Zimmerman, R.K., Tabbarah, M., Nowalk, M.P., Raymund, M., Jewell, I.K., Wilson, S.A. and Ricci, E.M. (2006) 'Racial differences in beliefs about genetic screening among patients at inner-city neighborhood health centers', Journal of the National Medical Association, Vol. 98, No. 3, pp. 370-377.