An R-type Ca2+ current in neurohypophysial terminals preferentially regulates oxytocin secretion

Journal of Neuroscience

Volumn 19, Issue 21, 1999, Pages 9235-9241

  Wang, Gang ^a,d   Dayanithi, Govindan ^b   Newcomb, Robert ^c   Lemos, José R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b CNRS   (France)

^c ELAN PHARMACEUTICALS   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Class E ( (1E)) Ca2+ channel; Oxytocin; Posterior pituitary; Secretion; SNX 482; Vasopressin

Indexed keywords

OXYTOCIN; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MEMBRANE DEPOLARIZATION; MOLECULAR CLONING; NERVE ENDING; NEUROHYPOPHYSIS; NEUROTRANSMITTER RELEASE; NONHUMAN; OXYTOCIN RELEASE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; STEADY STATE; STIMULUS SECRETION COUPLING; VASOPRESSIN RELEASE;

EID: 0033232710     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-21-09235.1999     Document Type: Article

References (43)

1. Augustine GJ, Charlton MP, Smith SJ (1987) Calcium action in synaptic transmitter release. Annu Rev Neurosci 10:633-693.
2. Bean BP (1989) Classes of calcium channels in vertebrate cells. Annu Rev Physiol 51:367-384.
3. Branchaw JL, Hsu SF, Jackson MB (1998) Membrane excitability and secretion from peptidergic nerve terminals. Cell Mol Neurobiol 18:45-63.
4. Cazalis M, Dayanithi G, Nordmann JJ (1987) Hormone release from isolated nerve endings of the rat neurohypophysis. J Physiol (Lond) 390:55-70.
5. Dayanithi G, Martin-Moutot N, Barlier S, Colin DA, Kretz-Zaepfel M, Coraud F, Nordmann JJ (1988) The calcium channel antagonist w-conotoxin inhibits secretion from peptidergic nerve terminals. Biochem Biophys Res Commun 156:255-262.
6. 2+ channels preferentially regulate oxytocin release from isolated rat neurohypophysial terminals. J Physiol (Lond) 515:134P-135P.
7. 2+ channels in mammalian central neurons. Trends Neurosci 18:89-98.
8. Ellinor PT, Zhang JF, Randall AD, Zhou M, Schwartz TL, Tsien RW, Horne WA (1993) Functional expression of a rapidly inactivating neuronal calcium channel. Nature 363:455-458.
9. Fisher TE, Bourque CW (1995) Distinct ω-agatoxin-sensitive calcium currents in somata and axon terminals of rat supraoptic neurones. J Physiol (Lond) 489:383-388.
10. Fisher TE, Bourque CW (1996) Calcium channel subtypes in the somata and axon terminals of magnocellular neurosecretory cells. Trends Neurosci 19:440-444.
11. Fox AP, Nowycky MC, Tsien RW (1987) Kinetic and pharmacological properties distinguishing three types of calcium currents in chicken sensory neurones. J Physiol (Lond) 394:149-172.
12. Gainer H, Chin H (1998) Molecular diversity in neurosecretion: reflections on the hypothalamo-neurohypophysial system. Cell Mol Neurobiol 18:211-230.
13. Gaur S, Newcomb R, Rivary B, Bell JR, Yamashiro D, Ramachandran J, Miljanich GP (1994) Calcium channel antagonist peptides define several components of transmitter release in the hippocampus. Neuropharmacology 33:1211-1219.
14. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells to cell-free membrane patches. Pflügers Arch 391:85-100.
15. 2+ channels. Neuron 9:69-77.
16. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 239:57-61.
17. Lemos JR, Nowycky MC (1989) Two types of calcium channels coexist in peptide-releasing vertebrate nerve terminals. Neuron 2:1419-1426.
18. Lim N, Nowycky MC, Bookman RJ (1990) Direct measurement of exocytosis and calcium currents in single vertebrate nerve terminals. Nature 344:449-451.
19. Lindau M, Stuenkel EL, Nordmann JJ (1992) Depolarization intracellular calcium and exocytosis in single vertebrate nerve endings. Biophys J 61:19-30.
20. 2+ channels in the mammalian central nervous system. Trends Neurosci 15:351-355.
21. Mintz IM, Venema VJ, Swiderek KM, Lee TD, Bean BP, Adams ME (1992) P-type calcium channels blocked by the spider toxin ω-Aga-IVA. Nature 355:827-829.
22. Newcomb R, Szoke B, Palma A, Wang G, Chen X, Hopkins W, Cong R, Miller J, Tarczy-Hornoch K, Loo JA, Dooley DJ, Nadasdi L, Tsien RW, Lemos JR, Miljanich G (1998) A selective peptide antagonist of the class E calcium channel from the venom of the tarantula, Hysterocrates gigas. Biochemistry 37:15353-15362.
23. Nordmann JJ, Dayanithi G, Lemos JR (1987) Isolated neurosecretory nerve endings as a tool for studying the mechanism of stimulus-secretion-coupling. Biosci Rep 7:411-426.
24. Olivera BM, Mcintosh JM, Cruz LT, Luque FA, Grey WR (1984) Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23:5087-5090.
25. Olivera BM, Miljanich GP, Ramachandran J, Adams ME (1994) Calcium channels diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins. Annu Rev Biochem 63:823-867.
26. Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (1998) Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Science 991:896-900.
27. Rae J, Cooper K, Gates P, Watsky M (1991) Low access resistance perforated patch recording using amphotericin B. J Neurosci Methods 37:15-26.
28. Ramachandran J, Nadasidi L, Ghil K, Kristipati R, Tarczy-Hornoch KT, Gaur S, Singh T, Bell J, Miljanich G (1993) Novel conopeptides reveal neuronal calcium channel diversity. In: Perspectives in medical chemistry (Testa B, Kyburz E, Fuhrer W, Giger RP, eds), pp 375-388. New York: VCH.
29. 2+ channel currents in rat cerebellar granule neurons. J Neurosci 15:2995-3012.
30. 1, subunits. Neuron 11:291-303.
31. 2+ channels: diversity of form and function. Curr Opin Neurobiol 2:247-253.
32. 2+ channels. Trends Pharmacol Sci 12:349-354.
33. 2+ currents in neurohypophysial terminals. Brain Res 663:215-222.
34. 2+ channels in vasopressin secretion from neurohypophysial terminals of the rat. J Physiol (Lond) 502:354-363.
35. 2+ channels preferentially regulate oxytocin release from neurohypophysial terminals. Biophys J 72:A367.
36. Wang XM, Treistman SN, Lemos JR (1992) Two types of high-threshold calcium currents inhibited by ω-conotoxin in nerve terminals of rat neurohypophysis. J Physiol (Lond) 445:181-199.
37. t-type calcium channels in rat neurohypophysial terminals. J Neurophysiol 70:1617-1628.
38. 2+ channels and peptide release from neurosecretory terminals. News Physiol Sci 8:64-68.
39. 1A, A subunits of brain calcium channels. J Neurosci 15:6403-6418.
40. 2+ channels in supporting hippocampal synaptic transmission. Science 264:107-111.
41. ++ currents evoke transmitter release at a rat central synapse. Proc Natl Acad Sci USA 95:4720-4725.
42. Wu LG, Westenbroek RE, Borst JG, Caterall WA, Sakmann B (1999) Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses. J Neurosci 19:726-736.
43. 2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology 32:1075-1088.