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Volumn 9780521848497, Issue , 2007, Pages 65-80

Insulin sensitizers in the treatment of polycystic ovary syndrome

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EID: 34347375421     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511545191.006     Document Type: Chapter
Times cited : (3)

References (63)
  • 1
    • 0036283875 scopus 로고    scopus 로고
    • Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: Amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance
    • Arslanian S. A., Lewy V., Danadian K., and Saad R. (2002) Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance. J. Clin. Endocrinol. Metab. 87:1555-1559.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 1555-1559
    • Arslanian, S.A.1    Lewy, V.2    Danadian, K.3    Saad, R.4
  • 2
    • 0035041906 scopus 로고    scopus 로고
    • Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: A multicenter, double blind, placebo-controlled trial
    • Azziz R., Ehrmann D., Legro R. S., et al. (2001) Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial. J. Clin. Endocrinol. Metab. 86:1626-1631.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 1626-1631
    • Azziz, R.1    Ehrmann, D.2    Legro, R.S.3
  • 3
    • 2942642477 scopus 로고    scopus 로고
    • The prevalence and features of the polycystic ovary syndrome in an unselected population
    • Azziz R., Woods K., Reyna R., et al. (2004) The prevalence and features of the polycystic ovary syndrome in an unselected population. J. Clin. Endocrinol. Metab. 89:2745-2749.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 2745-2749
    • Azziz, R.1    Woods, K.2    Reyna, R.3
  • 4
    • 5144220551 scopus 로고    scopus 로고
    • EVects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity
    • Baillargeon J. P., Jakubowicz D. J., Iuorno M. J., Jakubowicz S., and Nestler J. E. (2004) EVects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity. Fertil. Steril. 82:893-902.
    • (2004) Fertil. Steril , vol.82 , pp. 893-902
    • Baillargeon, J.P.1    Jakubowicz, D.J.2    Iuorno, M.J.3    Jakubowicz, S.4    Nestler, J.E.5
  • 6
    • 2942657650 scopus 로고    scopus 로고
    • Medical consequences of obesity
    • Bray G. (2004) Medical consequences of obesity. J. Clin. Endocrinol. Metab. 89:2583-2589.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 2583-2589
    • Bray, G.1
  • 7
    • 4043100289 scopus 로고    scopus 로고
    • EVect of the insulin sensitizer pioglitazone on insulin resistance, hyperandrogenism, and ovulatory dysfunction in women with polycystic ovary syndrome
    • Brettenthaler N., De Geyter C., Huber P. R., and Keller U. (2004) EVect of the insulin sensitizer pioglitazone on insulin resistance, hyperandrogenism, and ovulatory dysfunction in women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 89:3835-3840.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 3835-3840
    • Brettenthaler, N.1    De Geyter, C.2    Huber, P.R.3    Keller, U.4
  • 8
    • 0036198052 scopus 로고    scopus 로고
    • Anti-androgens for the treatment of hirsutism
    • Carmina E. (2002) Anti-androgens for the treatment of hirsutism. Exp. Opin. Invest. Drugs 11:357-363.
    • (2002) Exp. Opin. Invest. Drugs , vol.11 , pp. 357-363
    • Carmina, E.1
  • 9
    • 0027966932 scopus 로고
    • Obesity, fat distribution and weight gain as risk factors for clinical diabetes in men
    • Chan J., Rimm E., Colditz G., Stampfer M., and Willett W. (1994) Obesity, fat distribution and weight gain as risk factors for clinical diabetes in men. Diabetes Care 17:961-969.
    • (1994) Diabetes Care , vol.17 , pp. 961-969
    • Chan, J.1    Rimm, E.2    Colditz, G.3    Stampfer, M.4    Willett, W.5
  • 10
    • 0038245195 scopus 로고    scopus 로고
    • Clinical, metabolic and endocrine parameters in response to metformin in obese women with polycystic ovary syndrome: A randomized, double-blind and placebo-controlled trial
    • Chou K. H., von Eye Corleta H., Capp E., and Spritzer P. M. (2003) Clinical, metabolic and endocrine parameters in response to metformin in obese women with polycystic ovary syndrome: a randomized, double-blind and placebo-controlled trial. Horm. Metab. Res. 35:86-91.
    • (2003) Horm. Metab. Res , vol.35 , pp. 86-91
    • Chou, K.H.1    von Eye Corleta, H.2    Capp, E.3    Spritzer, P.M.4
  • 11
    • 0034069373 scopus 로고    scopus 로고
    • Combined oral contraceptive treatment of adolescent girls with polycystic ovary syndrome
    • Creatas G., Koliopoulos C., and Mastorakos G. (2000) Combined oral contraceptive treatment of adolescent girls with polycystic ovary syndrome. Ann. N. Y. Acad. Sci. 900:245-252.
    • (2000) Ann. N. Y. Acad. Sci , vol.900 , pp. 245-252
    • Creatas, G.1    Koliopoulos, C.2    Mastorakos, G.3
  • 12
    • 0142185995 scopus 로고    scopus 로고
    • Insulin-lowering agents in the management of polycystic ovary syndrome
    • De Leo V., la Marca A., and Petraglia F. (2003) Insulin-lowering agents in the management of polycystic ovary syndrome. Endocr. Rev. 24:633-637.
    • (2003) Endocr. Rev , vol.24 , pp. 633-637
    • De Leo, V.1    la Marca, A.2    Petraglia, F.3
  • 13
    • 0031957333 scopus 로고    scopus 로고
    • Therapeutic eVects of metformin on insulin resistance and hyperandrogenism in polycystic ovary syndrome
    • Diamanti-Kandarakis E., Kouli C., Tsianateli T., and Bergiele A. (1998) Therapeutic eVects of metformin on insulin resistance and hyperandrogenism in polycystic ovary syndrome. Eur. J. Endocrinol. 138:269-274.
    • (1998) Eur. J. Endocrinol , vol.138 , pp. 269-274
    • Diamanti-Kandarakis, E.1    Kouli, C.2    Tsianateli, T.3    Bergiele, A.4
  • 14
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
    • Dunaif A. (1997) Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr. Rev. 18:774-800.
    • (1997) Endocr. Rev , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 15
    • 0031015005 scopus 로고    scopus 로고
    • EVects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome
    • Ehrmann D. A., Cavaghan M. K., Imperial J., et al. (1997) EVects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 82:524-530.
    • (1997) J. Clin. Endocrinol. Metab , vol.82 , pp. 524-530
    • Ehrmann, D.A.1    Cavaghan, M.K.2    Imperial, J.3
  • 16
    • 0036063322 scopus 로고    scopus 로고
    • Clinical, endocrine and metabolic eVects of metformin added to ethinyl estradiol-cyproterone acetate in non-obese women with polycystic ovarian syndrome: A randomized controlled study
    • Elter K., Imir G., and Durmusoglu F. (2002) Clinical, endocrine and metabolic eVects of metformin added to ethinyl estradiol-cyproterone acetate in non-obese women with polycystic ovarian syndrome: a randomized controlled study. Hum. Reprod. 17:1729-1737.
    • (2002) Hum. Reprod , vol.17 , pp. 1729-1737
    • Elter, K.1    Imir, G.2    Durmusoglu, F.3
  • 17
    • 0033804645 scopus 로고    scopus 로고
    • Treatment of hirsutism with ethinyl estradiol-desogestrel contraceptive pills has beneficial eVects on the lipid profile and improves insulin sensitivity
    • Escobar-Morreale H. F., Miguel L., and Jose S. (2000) Treatment of hirsutism with ethinyl estradiol-desogestrel contraceptive pills has beneficial eVects on the lipid profile and improves insulin sensitivity. Fertil. Steril. 74:816-819.
    • (2000) Fertil. Steril , vol.74 , pp. 816-819
    • Escobar-Morreale, H.F.1    Miguel, L.2    Jose, S.3
  • 18
    • 0036170744 scopus 로고    scopus 로고
    • Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind placebo-controlled trial
    • Fleming R., Hopkinson Z. E., Wallace A. M., Greer I. A., and Sattar N. (2002) Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind placebo-controlled trial. J. Clin. Endocrinol. Metab. 87:569-574.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 569-574
    • Fleming, R.1    Hopkinson, Z.E.2    Wallace, A.M.3    Greer, I.A.4    Sattar, N.5
  • 19
    • 2942677215 scopus 로고    scopus 로고
    • Comparison of eYcacy of spironolactone with metformin in the management of polycystic ovary syndrome: An open-labeled study
    • Ganie M. A., Khurana M. L., Eunice M., et al. (2004) Comparison of eYcacy of spironolactone with metformin in the management of polycystic ovary syndrome: an open-labeled study. J. Clin. Endocrinol. Metab. 89:2756-2762.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 2756-2762
    • Ganie, M.A.1    Khurana, M.L.2    Eunice, M.3
  • 20
    • 0036181614 scopus 로고    scopus 로고
    • Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome
    • Glueck C. J., Wang P., Kobayashi S., Phillips H., and Sieve-Smith L. (2002) Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome. Fertil. Steril. 77:520-525.
    • (2002) Fertil. Steril , vol.77 , pp. 520-525
    • Glueck, C.J.1    Wang, P.2    Kobayashi, S.3    Phillips, H.4    Sieve-Smith, L.5
  • 22
    • 0042624707 scopus 로고    scopus 로고
    • Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally responsive to metformin
    • Glueck C. J., Moreira A., Goldenberg N., Sieve L., and Wang P. (2003b) Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally responsive to metformin. Hum. Reprod. 18:1618-1625.
    • (2003) Hum. Reprod , vol.18 , pp. 1618-1625
    • Glueck, C.J.1    Moreira, A.2    Goldenberg, N.3    Sieve, L.4    Wang, P.5
  • 23
    • 3042685726 scopus 로고    scopus 로고
    • Height, weight, and motor-social development during the first 18 months of life in 126 infants born to 109 mothers with polycystic ovary syndrome who conceived on and continued metformin through pregnancy
    • Glueck C. J., Goldenberg N., PranikoV J., et al. (2004) Height, weight, and motor-social development during the first 18 months of life in 126 infants born to 109 mothers with polycystic ovary syndrome who conceived on and continued metformin through pregnancy. Hum. Reprod. 19:1323-1330.
    • (2004) Hum. Reprod , vol.19 , pp. 1323-1330
    • Glueck, C.J.1    Goldenberg, N.2    PranikoV, J.3
  • 24
    • 0025201663 scopus 로고
    • The eVects of diVerent formulations of oral contraceptive agents on lipid and carbohydrate metabolism
    • Godsland I. F., Crook D., Simpson R., et al. (1990) The eVects of diVerent formulations of oral contraceptive agents on lipid and carbohydrate metabolism. N. Engl. J. Med. 323:1375-1380.
    • (1990) N. Engl. J. Med , vol.323 , pp. 1375-1380
    • Godsland, I.F.1    Crook, D.2    Simpson, R.3
  • 25
    • 0346725827 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long term health risks related to polycystic ovary syndrome
    • Group TREAC (2004) Revised 2003 consensus on diagnostic criteria and long term health risks related to polycystic ovary syndrome. Fertil. Steril. 81:19-25.
    • (2004) Fertil. Steril , vol.81 , pp. 19-25
  • 26
    • 0036177070 scopus 로고    scopus 로고
    • EVect of hypertension therapy with the angiotensin-converting enzyme inhibitor lisinopril on hyperandrogenism in women with polycystic ovary syndrome
    • Hacihanefioglu B., Somunkiran A., Mahmutoglu I., et al. (2002) EVect of hypertension therapy with the angiotensin-converting enzyme inhibitor lisinopril on hyperandrogenism in women with polycystic ovary syndrome. Fertil. Steril. 77:526-528.
    • (2002) Fertil. Steril , vol.77 , pp. 526-528
    • Hacihanefioglu, B.1    Somunkiran, A.2    Mahmutoglu, I.3
  • 27
    • 0141676042 scopus 로고    scopus 로고
    • Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome
    • Harborne L., Fleming R., Lyall H., Sattar N., and Norman J. (2003) Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 88:4166-4171.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 4166-4171
    • Harborne, L.1    Fleming, R.2    Lyall, H.3    Sattar, N.4    Norman, J.5
  • 28
    • 0029142760 scopus 로고
    • Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome
    • Holte J., Bergh T., Berne C., Wilde L., and Lithell H. (1995) Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 80:2586-2593.
    • (1995) J. Clin. Endocrinol. Metab , vol.80 , pp. 2586-2593
    • Holte, J.1    Bergh, T.2    Berne, C.3    Wilde, L.4    Lithell, H.5
  • 29
    • 0030047162 scopus 로고    scopus 로고
    • Elevated daytime blood pressure in women with polycystic ovary syndrome: A sign of a pre-hypertensive state?
    • Holte J., Gennarelli G., Berne C., Bergh T., and Lithell H. (1996) Elevated daytime blood pressure in women with polycystic ovary syndrome: a sign of a pre-hypertensive state? Hum. Reprod. 11:23-28.
    • (1996) Hum. Reprod , vol.11 , pp. 23-28
    • Holte, J.1    Gennarelli, G.2    Berne, C.3    Bergh, T.4    Lithell, H.5
  • 30
    • 0034456568 scopus 로고    scopus 로고
    • Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans
    • Katz A., Nambi S. S., Mather K., et al. (2000) Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J. Clin. Endocrinol. Metab. 85:2402-2410.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 2402-2410
    • Katz, A.1    Nambi, S.S.2    Mather, K.3
  • 31
    • 0037034257 scopus 로고    scopus 로고
    • Diabetes Prevention Program Research Group: Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler W., Barrett-Connor E., Fowler S., et al. (2002) Diabetes Prevention Program Research Group: Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346:393-403.
    • (2002) N. Engl. J. Med , vol.346 , pp. 393-403
    • Knowler, W.1    Barrett-Connor, E.2    Fowler, S.3
  • 32
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 aVected women
    • Legro R. S., Kunselman A. R., Dodson W. C., and Dunaif A. (1999) Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 aVected women. J. Clin. Endocrinol. Metab. 84:165-168.
    • (1999) J. Clin. Endocrinol. Metab , vol.84 , pp. 165-168
    • Legro, R.S.1    Kunselman, A.R.2    Dodson, W.C.3    Dunaif, A.4
  • 33
    • 0141724824 scopus 로고    scopus 로고
    • Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome
    • Lord J. M., Flight I. H., and Norman R. J. (2003) Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome. Cochrane Database Syst Rev. 3:CD003053.
    • (2003) Cochrane Database Syst Rev , vol.3
    • Lord, J.M.1    Flight, I.H.2    Norman, R.J.3
  • 34
    • 23844531493 scopus 로고    scopus 로고
    • Vascular dysfunction and metabolic parameters in polycystic ovary syndrome
    • Meyer C., McGrath B., Cameron J., and Teede H. J. (2005) Vascular dysfunction and metabolic parameters in polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 90:4630-4635.
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , pp. 4630-4635
    • Meyer, C.1    McGrath, B.2    Cameron, J.3    Teede, H.J.4
  • 35
    • 26244450785 scopus 로고    scopus 로고
    • Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular disease
    • Meyer C. M. B. and Teede H. J. (2005) Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular disease. J. Clin. Endocrinol. Metab. 90: 5711-5716.
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , pp. 5711-5716
    • Meyer, C.M.B.1    Teede, H.J.2
  • 36
    • 0034458234 scopus 로고    scopus 로고
    • Metformin eVects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation
    • Moghetti P., Castello R., Negri C., et al. (2000) Metformin eVects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J. Clin. Endocrinol. Metab. 85:139-146.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 139-146
    • Moghetti, P.1    Castello, R.2    Negri, C.3
  • 37
    • 0037326171 scopus 로고    scopus 로고
    • Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome
    • Moran L. J., Noakes M., Clifton P. M., Tomlinson L., and Norman R. J. (2003) Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 88:812-819.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 812-819
    • Moran, L.J.1    Noakes, M.2    Clifton, P.M.3    Tomlinson, L.4    Norman, R.J.5
  • 38
    • 0033710083 scopus 로고    scopus 로고
    • Endocrine and metabolic eVects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: A randomized study
    • Morin-Papunen L. C., Vauhkonen I., Koivunen R. M., et al. (2000) Endocrine and metabolic eVects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study. J. Clin. Endocrinol. Metab. 85:3161-3168.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 3161-3168
    • Morin-Papunen, L.C.1    Vauhkonen, I.2    Koivunen, R.M.3
  • 40
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler J. E. and Jakubowicz D. J. (1996) Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N. Engl. J. Med. 335:617-623.
    • (1996) N. Engl. J. Med , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 41
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens
    • Nestler J. E. and Jakubowicz D. J. (1997) Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens. J. Clin. Endocrinol. Metab. 82:4075-4079.
    • (1997) J. Clin. Endocrinol. Metab , vol.82 , pp. 4075-4079
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 42
    • 0028837055 scopus 로고
    • Metabolic approaches to the subclassification of polycystic ovary syndrome
    • Norman R. J., Masters S. C., Hague W., et al. (1995) Metabolic approaches to the subclassification of polycystic ovary syndrome. Fertil. Steril. 63:329-335.
    • (1995) Fertil. Steril , vol.63 , pp. 329-335
    • Norman, R.J.1    Masters, S.C.2    Hague, W.3
  • 43
    • 0034815278 scopus 로고    scopus 로고
    • Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome
    • Norman R. J., Masters L., Milner C. R., Wang J. X., and Davies M. J. (2001) Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome. Hum. Reprod. 16:1995-1998.
    • (2001) Hum. Reprod , vol.16 , pp. 1995-1998
    • Norman, R.J.1    Masters, L.2    Milner, C.R.3    Wang, J.X.4    Davies, M.J.5
  • 44
    • 23044513823 scopus 로고    scopus 로고
    • Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome
    • Palomba S., Orio Jr. F., Falbo A., et al. (2005) Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 90:4068-4074.
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , pp. 4068-4074
    • Palomba, S.1    Orio, F.2    Falbo, A.3
  • 45
    • 0037326410 scopus 로고    scopus 로고
    • Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome
    • Paradisi G., Steinberg H., Shepard M., Hook G., and Baron A.D. (2003) Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 88:576-580.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 576-580
    • Paradisi, G.1    Steinberg, H.2    Shepard, M.3    Hook, G.4    Baron, A.D.5
  • 46
    • 17744400090 scopus 로고    scopus 로고
    • EVect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome
    • Pasquali R., Gambineri A., Biscotti D., et al. (2000) EVect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 85:2767-2775.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 2767-2775
    • Pasquali, R.1    Gambineri, A.2    Biscotti, D.3
  • 47
    • 2042548063 scopus 로고    scopus 로고
    • Mortality of women with polycystic ovary syndrome at long term follow-up
    • Pierpoint T., McKeigue P., Isaacs A., Wild S., and Jacobs H. (1998) Mortality of women with polycystic ovary syndrome at long term follow-up. J. Clin. Epidemiol. 51:581-586.
    • (1998) J. Clin. Epidemiol , vol.51 , pp. 581-586
    • Pierpoint, T.1    McKeigue, P.2    Isaacs, A.3    Wild, S.4    Jacobs, H.5
  • 48
    • 0041563930 scopus 로고    scopus 로고
    • Laparoscopic treatment of polycystic ovaries: Is it time to relinquish the procedure?
    • Pirwany I. and Tulandi T. (2003) Laparoscopic treatment of polycystic ovaries: is it time to relinquish the procedure? Fertil. Steril. 80:241-251.
    • (2003) Fertil. Steril , vol.80 , pp. 241-251
    • Pirwany, I.1    Tulandi, T.2
  • 49
    • 0034485313 scopus 로고    scopus 로고
    • Insulin sensitivity and its measurement: Structural commonalities among the methods
    • Radziuk J. (2000) Insulin sensitivity and its measurement: structural commonalities among the methods. J. Clin. Endocrinol. Metab. 85:4426-4433.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 4426-4433
    • Radziuk, J.1
  • 50
    • 0038508940 scopus 로고    scopus 로고
    • Selective eVects of pioglitazone on insulin and androgen abnormalities in normo-and hyperinsulinaemic obese patients with polycystic ovary syndrome
    • Romualdi D., Guido M., Ciampelli M., et al. (2003) Selective eVects of pioglitazone on insulin and androgen abnormalities in normo-and hyperinsulinaemic obese patients with polycystic ovary syndrome. Hum. Reprod. 18:1210-1218.
    • (2003) Hum. Reprod , vol.18 , pp. 1210-1218
    • Romualdi, D.1    Guido, M.2    Ciampelli, M.3
  • 51
    • 0344420380 scopus 로고    scopus 로고
    • Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus
    • Salpeter S., Greyber E., Pasternak G., and Salpeter E. (2003) Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Arch. Intern. Med. 163:2594-2602.
    • (2003) Arch. Intern. Med , vol.163 , pp. 2594-2602
    • Salpeter, S.1    Greyber, E.2    Pasternak, G.3    Salpeter, E.4
  • 52
    • 0029847586 scopus 로고    scopus 로고
    • Ambulatory blood pressure profiles and plasminogen activator inhibitor (PAI-1) activity in lean women with and without the polycystic ovary syndrome
    • Sampson M., Kong C., Patel A., Unwin R., and Jacobs H. S. (1996) Ambulatory blood pressure profiles and plasminogen activator inhibitor (PAI-1) activity in lean women with and without the polycystic ovary syndrome. Clin. Endocrinol. (Oxf.) 45:623-629.
    • (1996) Clin. Endocrinol. (Oxf.) , vol.45 , pp. 623-629
    • Sampson, M.1    Kong, C.2    Patel, A.3    Unwin, R.4    Jacobs, H.S.5
  • 53
    • 12244251426 scopus 로고    scopus 로고
    • EVects of rosiglitazone in obese women with polycystic ovary syndrome and severe insulin resistance
    • Sepilian V. and Nagamani M. (2005) EVects of rosiglitazone in obese women with polycystic ovary syndrome and severe insulin resistance. J. Clin. Endocrinol. Metab. 90:60-65.
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , pp. 60-65
    • Sepilian, V.1    Nagamani, M.2
  • 54
    • 0031901117 scopus 로고    scopus 로고
    • Adverse lipid and coronary heart disease profiles in young women with polycystic ovary syndrome: Results of a case control study
    • Talbot E., Clerici A., and Berga S. (1998) Adverse lipid and coronary heart disease profiles in young women with polycystic ovary syndrome: results of a case control study. J. Clin. Epidemiol. 51:415-422.
    • (1998) J. Clin. Epidemiol , vol.51 , pp. 415-422
    • Talbot, E.1    Clerici, A.2    Berga, S.3
  • 55
    • 0035145624 scopus 로고    scopus 로고
    • Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in pateints with polycystic ovarian syndrome who are resistant to clomiphene citrate alone
    • Vandermolen D. T. R. V., Evans W. S., Stovall D.W., Kauma S.W., and Nestler J. E. (2001) Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in pateints with polycystic ovarian syndrome who are resistant to clomiphene citrate alone. Fertil. Steril. 75:310-315.
    • (2001) Fertil. Steril , vol.75 , pp. 310-315
    • Vandermolen, D.T.R.V.1    Evans, W.S.2    Stovall, D.W.3    Kauma, S.W.4    Nestler, J.E.5
  • 56
    • 0028315971 scopus 로고
    • Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy
    • Velazquez E., Mendosa S., Hamer T., Sosa F., and Glueck C. (1994) Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy. Metabolism 43:647-654.
    • (1994) Metabolism , vol.43 , pp. 647-654
    • Velazquez, E.1    Mendosa, S.2    Hamer, T.3    Sosa, F.4    Glueck, C.5
  • 57
    • 0028959137 scopus 로고
    • Obesity, lipids, cardiovascular risk, and androgen excess
    • Wild R. A. (1995) Obesity, lipids, cardiovascular risk, and androgen excess. Am. J. Med. 98:27S-32S.
    • (1995) Am. J. Med , vol.98 , pp. 27S-32S
    • Wild, R.A.1
  • 58
    • 0022354308 scopus 로고
    • Lipoprotein lipid concentrations and cardiovascular risk inwomen with polycystic ovarian syndrome
    • Wild R. A., Painter P., Coulson P., Carruth K., and Ranney G. (1985) Lipoprotein lipid concentrations and cardiovascular risk inwomen with polycystic ovarian syndrome. J. Clin. Endocrinol. Metab. 61:946-951.
    • (1985) J. Clin. Endocrinol. Metab , vol.61 , pp. 946-951
    • Wild, R.A.1    Painter, P.2    Coulson, P.3    Carruth, K.4    Ranney, G.5
  • 59
    • 0034078044 scopus 로고    scopus 로고
    • Cardiovascular disease in women with polycystic ovary syndrome at longterm follow-up: A retrospective cohort study
    • Wild S., Pierpoint T., McKeigue P., and Jacobs H. (2000) Cardiovascular disease in women with polycystic ovary syndrome at longterm follow-up: a retrospective cohort study. Clin. Endocrinol. (Oxf.) 52:595-600.
    • (2000) Clin. Endocrinol. (Oxf.) , vol.52 , pp. 595-600
    • Wild, S.1    Pierpoint, T.2    McKeigue, P.3    Jacobs, H.4
  • 60
    • 0036177496 scopus 로고    scopus 로고
    • Co-administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: A prospective randomized trial
    • Yarali H., Yildiz B.O., Demirol A., et al. (2002) Co-administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: a prospective randomized trial. Hum. Reprod. 17:289-294.
    • (2002) Hum. Reprod , vol.17 , pp. 289-294
    • Yarali, H.1    Yildiz, B.O.2    Demirol, A.3
  • 61
    • 5444275864 scopus 로고    scopus 로고
    • Recent advances in the treatment of polycystic ovarian syndrome
    • Yildiz B. (2004) Recent advances in the treatment of polycystic ovarian syndrome. Exp. Opin. Invest. Drugs 13:1295-1305.
    • (2004) Exp. Opin. Invest. Drugs , vol.13 , pp. 1295-1305
    • Yildiz, B.1
  • 62
    • 19244365650 scopus 로고    scopus 로고
    • Drug therapy: Thiazolidinediones
    • Yki-Jarvinen H. (2004) Drug therapy: thiazolidinediones. N. Engl. J. Med. 351:1106-1118.
    • (2004) N. Engl. J. Med , vol.351 , pp. 1106-1118
    • Yki-Jarvinen, H.1
  • 63
    • 0001217801 scopus 로고
    • Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach
    • Dunaif A. and Givens J. F. H. (eds.), Cambridge, MA: Blackwell Scientific
    • Zawadzki J. and Dunaif A. (1992) Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In Dunaif A. and Givens J. F. H. (eds.) Polycystic Ovary Syndrome, pp. 377-384. Cambridge, MA: Blackwell Scientific.
    • (1992) Polycystic Ovary Syndrome , pp. 377-384
    • Zawadzki, J.1    Dunaif, A.2


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