Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind placebo-controlled trial

Journal of Clinical Endocrinology and Metabolism

Volumn 87, Issue 2, 2002, Pages 569-574

  Fleming, Richard ^a   Hopkinson, Zoe E ^a   Michael Wallace, A ^a   Greer, Ian A ^a   Sattar, Naveed ^a  

^a GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN; PLACEBO;

ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HUMAN; INSULIN RESISTANCE; INSULIN RESPONSE; METABOLIC ACTIVATION; OLIGOMENORRHEA; OVARY FOLLICLE MATURATION; OVARY FUNCTION; OVARY POLYCYSTIC DISEASE; OVULATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS;

FALLOPIA;

EID: 0036170744     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.87.2.8261     Document Type: Article

References (25)

1. Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
2. Polycystic ovary syndrome: The metabolic syndrome comes to gynaecology
3. Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance
4. Dyslipidaerrua is associated with insulin resistance in women with polycystic ovaries
5. Lipids and lipoprotein subfractions in women with PCOS: Relationship to metabolic and endocrine parameters
6. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
7. Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: A multicenter, double blind, placebo-controlled trial
8. Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome
9. Spontaneous follicular and luteal function in infertile women with oligomenorrhoea: Role of luteinizing hormone
10. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism
11. Induction of ovulation with low-dose gonadotropins in polycystic ovary syndrome: An analysis of 109 pregnancies in 225 women
12. Effects of the insulin sensitizing drug metformin on ovarian function, follicular growth and ovulation rate in obese women with oligomenorrhoea
13. Differences in circulating concentrations of total, free and bound leptin relate to gender and body composition in adult humans
14. Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation
15. Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome
16. Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome
17. Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17α hydroxylase activity and serum androgens
18. Effects of metformin on adrenal steroidogenesis in women with polycystic ovary syndrome
19. Effects of laparoscopic ovarian drilling on adrenal steroids in polycystic ovary syndrome patients with and without hyperinsulinaemia
20. Mefformin therapy decreases hyperandrogenism and hyperinsulinaemia in women with polycystic ovary syndrome
21. Troglitazone inhibits progesterone production in porcine granulosa cells
22. Insulin sensitizers and polycystic ovary syndrome; Can a diabetes medication treat infertility?
23. Weight loss in obese infertile women results in improvement in the reproductive outcome for all forms of fertility treatment