The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes

Molecular Pharmacology

Volumn 71, Issue 6, 2007, Pages 1685-1694

  Raoux, Matthieu ^a   Colomban, Cécile ^b   Delmas, Patrick ^a   Crest, Marcel ^a,c  

^a CNRS   (France)

^b Eurofins Medinet Inc   (Germany)

^c AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ANION CHANNEL; CALCIUM; HEPTYLAMINE; HYPOTONIC SOLUTION; IRRITANT AGENT; ISOTONIC SOLUTION; UNCLASSIFIED DRUG; VOLUME REGULATED ANION CHANNEL;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CALCIUM MOBILIZATION; CELL MEMBRANE TRANSPORT; CELL SWELLING; CONCENTRATION RESPONSE; CONTACT DERMATITIS; CONTROLLED STUDY; CYTOSOL; EPIDERMIS CELL; HUMAN; HUMAN CELL; IC 50; ION CONDUCTANCE; ION CURRENT; KERATINOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SKIN IRRITATION; SKIN TOXICITY;

AMINES; ANIONS; ANTIPORTERS; CALCIUM; CELLS, CULTURED; CYTOPLASM; EPIDERMIS; HUMANS; IRRITANTS; KERATINOCYTES;

EID: 34347337697     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.033324     Document Type: Article

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