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Volumn 163, Issue 6-7, 2007, Pages 651-655

Experimental models of multiple sclerosis

Author keywords

Autoimmune encephalomyelitis; Axonal injury; Demyelination; Inflammation; Multiple sclerosis

Indexed keywords

AUTOIMMUNITY; AXONAL INJURY; CLINICAL FEATURE; CONFERENCE PAPER; DEMYELINATING DISEASE; DISEASE MODEL; ENCEPHALOMYELITIS; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; NONHUMAN;

EID: 34347333268     PISSN: 00353787     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-3787(07)90474-9     Document Type: Conference Paper
Times cited : (59)

References (40)
  • 1
    • 33646890625 scopus 로고    scopus 로고
    • ABOUL-ENEIN F, WEISER P, HÖ FTBERGER R, LASSMANN H, B RADL M. (2006). Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis. Acta Neuropathol (Berl), 111: 539-547.
    • ABOUL-ENEIN F, WEISER P, HÖ FTBERGER R, LASSMANN H, B RADL M. (2006). Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis. Acta Neuropathol (Berl), 111: 539-547.
  • 2
    • 0037226838 scopus 로고    scopus 로고
    • Preferential loss of myelin associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases
    • ABOUL-ENEIN F, RAUSCHKA H, KORNEL B et al. (2003). Preferential loss of myelin associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. J Neuropath Exp Neurol, 62: 25-33.
    • (2003) J Neuropath Exp Neurol , vol.62 , pp. 25-33
    • ABOUL-ENEIN, F.1    RAUSCHKA, H.2    KORNEL, B.3
  • 3
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • ALOISI F, PUJOL-BORRELL R. (2006). Lymphoid neogenesis in chronic inflammatory diseases. Nat. Rev. Immunol, 6: 205-217.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 205-217
    • ALOISI, F.1    PUJOL-BORRELL, R.2
  • 4
    • 0034618094 scopus 로고    scopus 로고
    • Clonal expansion of CD8+ T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
    • BABBE H, ROERS A, WAISMAN A et al. (2000). Clonal expansion of CD8+ T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J. Exp. Med, 192: 393-404.
    • (2000) J. Exp. Med , vol.192 , pp. 393-404
    • BABBE, H.1    ROERS, A.2    WAISMAN, A.3
  • 5
    • 0019465142 scopus 로고
    • The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
    • BEN-NUN A, WEKERLE H, COHEN IR. (1981). The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol, 11: 195-199.
    • (1981) Eur J Immunol , vol.11 , pp. 195-199
    • BEN-NUN, A.1    WEKERLE, H.2    COHEN, I.R.3
  • 6
    • 0030961807 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis: The antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system
    • BERGER T, WEERTH S, KOJIMA K, LININGTON C, WEKERLE H, LASSMANN H. (1997). Experimental autoimmune encephalomyelitis: the antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system. Lab Invest, 76: 355-364.
    • (1997) Lab Invest , vol.76 , pp. 355-364
    • BERGER, T.1    WEERTH, S.2    KOJIMA, K.3    LININGTON, C.4    WEKERLE, H.5    LASSMANN, H.6
  • 7
    • 0021079164 scopus 로고
    • Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis
    • BOOSS J, ESIRI MM, TOURTELLOTTE WW, MASON DY. (1983). Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis. J Neurol Sci, 62: 219-232.
    • (1983) J Neurol Sci , vol.62 , pp. 219-232
    • BOOSS, J.1    ESIRI, M.M.2    TOURTELLOTTE, W.W.3    MASON, D.Y.4
  • 8
    • 14844293538 scopus 로고    scopus 로고
    • BRINK BP, VEERHUIS R, BREIJ EC, VAN DER VALK P, DIJKSTRA CD, BO L. (2005). The pathology of multiple sclerosis is location dependent: no significant complement activation is detected in purely cortical lesions. J Neuropath Exp Neurol, 64: 147-155.
    • BRINK BP, VEERHUIS R, BREIJ EC, VAN DER VALK P, DIJKSTRA CD, BO L. (2005). The pathology of multiple sclerosis is location dependent: no significant complement activation is detected in purely cortical lesions. J Neuropath Exp Neurol, 64: 147-155.
  • 9
    • 0038297356 scopus 로고    scopus 로고
    • Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes
    • CABARROCAS J, BAUER J, PIAGGIO E, LIBLAU R, LASSMANN H. (2003). Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes. European Journal of Immunology, 33: 1174-1182.
    • (2003) European Journal of Immunology , vol.33 , pp. 1174-1182
    • CABARROCAS, J.1    BAUER, J.2    PIAGGIO, E.3    LIBLAU, R.4    LASSMANN, H.5
  • 10
    • 21944442728 scopus 로고    scopus 로고
    • Inflammation and primary demyelination induced by the intraspinal injections of lipopolysaccharide
    • FELTS PA, WOOLSTON AM, FERNANDO HB et al. (2005). Inflammation and primary demyelination induced by the intraspinal injections of lipopolysaccharide. Brain, 128: 1649-1666.
    • (2005) Brain , vol.128 , pp. 1649-1666
    • FELTS, P.A.1    WOOLSTON, A.M.2    FERNANDO, H.B.3
  • 11
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • FERGUSON B, MATYSZAK MK, ESIRI MM, PERRY VH. (1997). Axonal damage in acute multiple sclerosis lesions. Brain, 120: 393-399.
    • (1997) Brain , vol.120 , pp. 393-399
    • FERGUSON, B.1    MATYSZAK, M.K.2    ESIRI, M.M.3    PERRY, V.H.4
  • 12
    • 0035005143 scopus 로고    scopus 로고
    • Migratory activity and functional changes of green fluorescent effector cells before and during experiemntal autoimmune encephalomyelitis
    • FLUGEL A, BERKOWICZ T, RITTER T et al. (2001). Migratory activity and functional changes of green fluorescent effector cells before and during experiemntal autoimmune encephalomyelitis. Immunity, 14: 547-560.
    • (2001) Immunity , vol.14 , pp. 547-560
    • FLUGEL, A.1    BERKOWICZ, T.2    RITTER, T.3
  • 13
    • 23444434940 scopus 로고    scopus 로고
    • Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy?
    • FRIESE MA, FUGGER L. (2005). Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain, 128: 1747-1763.
    • (2005) Brain , vol.128 , pp. 1747-1763
    • FRIESE, M.A.1    FUGGER, L.2
  • 14
    • 1842367972 scopus 로고    scopus 로고
    • The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis: Identification and characterization of the primary demyelinating lesion
    • GAY FW, DRYE GW, DICK GWA, ESIRI MM. (1997). The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis: Identification and characterization of the primary demyelinating lesion. Brain, 120: 1461-1483.
    • (1997) Brain , vol.120 , pp. 1461-1483
    • GAY, F.W.1    DRYE, G.W.2    DICK, G.W.A.3    ESIRI, M.M.4
  • 15
    • 0036191226 scopus 로고    scopus 로고
    • Association of a null mutation in the CNTF gene with early onset of multiple sclerosis
    • GIESS R, MAURER M, LINKER R et al. (2002). Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. Arch-Neurol, 59: 407-409.
    • (2002) Arch-Neurol , vol.59 , pp. 407-409
    • GIESS, R.1    MAURER, M.2    LINKER, R.3
  • 16
    • 33746729791 scopus 로고    scopus 로고
    • Understanding pathogenesis and therapy of multiple sclerosis vial animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
    • GOLD R, LININGTON C, LASSMANN H. (2006). Understanding pathogenesis and therapy of multiple sclerosis vial animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain, 129: 1953-1971.
    • (2006) Brain , vol.129 , pp. 1953-1971
    • GOLD, R.1    LININGTON, C.2    LASSMANN, H.3
  • 17
    • 33748568160 scopus 로고    scopus 로고
    • Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis
    • HOCHMEISTER S, GRUNDTNER R, BAUER J et al. (2006). Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis. J Neuropath Exp Neurol, 65: 855-865.
    • (2006) J Neuropath Exp Neurol , vol.65 , pp. 855-865
    • HOCHMEISTER, S.1    GRUNDTNER, R.2    BAUER, J.3
  • 18
    • 1042299971 scopus 로고    scopus 로고
    • Expression of Major Histocompatibiltiy Complex Class I Molecules on the different Cell Types in Multiple Sclerosis lesions
    • HÖFTBERGER R, ABOUL-ENEIN F, BRUECK W et al. (2004). Expression of Major Histocompatibiltiy Complex Class I Molecules on the different Cell Types in Multiple Sclerosis lesions. Brain Pathol, 14: 43-50.
    • (2004) Brain Pathol , vol.14 , pp. 43-50
    • HÖFTBERGER, R.1    ABOUL-ENEIN, F.2    BRUECK, W.3
  • 19
    • 5144235394 scopus 로고    scopus 로고
    • Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: From pipe dreams to (therapeutic) pipelines
    • HOHLFELD R, WEKERLE H. (2004). Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines. Proc Natl Acad Sci (USA), 101(Suppl 2): 14599-14606
    • (2004) Proc Natl Acad Sci (USA) , vol.101 , Issue.SUPPL. 2 , pp. 14599-14606
    • HOHLFELD, R.1    WEKERLE, H.2
  • 21
    • 0028965522 scopus 로고    scopus 로고
    • KERLERO DE ROSBO N, MENDEL I, BEN NUN A. (1995). Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG) derrived peptide: preliminary analysis of MOG T-cell epitopes. Eur J Immunol, 25: 985-993.
    • KERLERO DE ROSBO N, MENDEL I, BEN NUN A. (1995). Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG) derrived peptide: preliminary analysis of MOG T-cell epitopes. Eur J Immunol, 25: 985-993.
  • 22
    • 27644552194 scopus 로고    scopus 로고
    • Cortical demyelination and diffuse white matter injury in multiple sclerosis
    • KUTZELNIGG A, LUCCHINETTI CF, STADELMANN C et al. (2005). Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain, 128: 2705-2712.
    • (2005) Brain , vol.128 , pp. 2705-2712
    • KUTZELNIGG, A.1    LUCCHINETTI, C.F.2    STADELMANN, C.3
  • 23
    • 0020655874 scopus 로고
    • Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis. Springer Schriftenr
    • LASSMANN H. (1983). Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis. Springer Schriftenr. Neurol, 25: 1-135.
    • (1983) Neurol , vol.25 , pp. 1-135
    • LASSMANN, H.1
  • 24
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
    • LININGTON C, BRADL M, LASSMANN H, BRUNNER C, VASS K. (1988). Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Amer J Pathol, 130: 443-454
    • (1988) Amer J Pathol , vol.130 , pp. 443-454
    • LININGTON, C.1    BRADL, M.2    LASSMANN, H.3    BRUNNER, C.4    VASS, K.5
  • 25
    • 0036281689 scopus 로고    scopus 로고
    • CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation
    • LINKER RA, MAURER M, GAUPP S et al. (2002). CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nat-Med, 8: 620-624.
    • (2002) Nat-Med , vol.8 , pp. 620-624
    • LINKER, R.A.1    MAURER, M.2    GAUPP, S.3
  • 26
    • 0027398906 scopus 로고
    • CNTF protection of oligodendrocytes against natura and tumor necrosis factor-induced death
    • LOUIS JC, MAGAL E, TAKAYAMA S, VARON S. (1993). CNTF protection of oligodendrocytes against natura and tumor necrosis factor-induced death. Science, 259: 689-692.
    • (1993) Science , vol.259 , pp. 689-692
    • LOUIS, J.C.1    MAGAL, E.2    TAKAYAMA, S.3    VARON, S.4
  • 27
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • LUCCHINETTI C, BRÜCK W, PARISI J, SCHEITHAUER, B, RODRIGUEZ M, LASSMANN, H. (2000). Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination. Ann Neurol, 47: 707-717.
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • LUCCHINETTI, C.1    BRÜCK, W.2    PARISI, J.3    SCHEITHAUER, B.4    RODRIGUEZ, M.5    LASSMANN, H.6
  • 28
    • 0000197889 scopus 로고
    • Die sogenannte "akute Multiple Sklerose" Jahrb
    • MARBURG O. (1906). Die sogenannte "akute Multiple Sklerose" Jahrb. Psychiatrie, 27: 211-312.
    • (1906) Psychiatrie , vol.27 , pp. 211-312
    • MARBURG, O.1
  • 29
    • 0034842960 scopus 로고    scopus 로고
    • Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes
    • MEDANA I, MARTINIC MA, WEKERLE H, NEUMANN H. (2001). Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol, 159: 809-815.
    • (2001) Am J Pathol , vol.159 , pp. 809-815
    • MEDANA, I.1    MARTINIC, M.A.2    WEKERLE, H.3    NEUMANN, H.4
  • 30
    • 33747886404 scopus 로고    scopus 로고
    • A new focal EAE model of cortical demyelination: MS-like lesions with rapid resolution of inflammation and extensive remyelination
    • MERKLER D, ERNSTING T, KERSCHENSTEINER M, BRÜCK W, STADELMANN C. (2006). A new focal EAE model of cortical demyelination: MS-like lesions with rapid resolution of inflammation and extensive remyelination. Brain, 129: 1972-1983
    • (2006) Brain , vol.129 , pp. 1972-1983
    • MERKLER, D.1    ERNSTING, T.2    KERSCHENSTEINER, M.3    BRÜCK, W.4    STADELMANN, C.5
  • 31
    • 0036602982 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases
    • NEUMANN H, MEDANA I, BAUER J, LASSMANN H. (2002). Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. Trend Neurosci, 25: 313-319.
    • (2002) Trend Neurosci , vol.25 , pp. 313-319
    • NEUMANN, H.1    MEDANA, I.2    BAUER, J.3    LASSMANN, H.4
  • 33
    • 0034842126 scopus 로고    scopus 로고
    • Transsected neurites, apoptotic neurons and reduced inflammation in cortical multiple sclerosis lesions
    • PETERSON JW, BO L, MORK S, CHANG A, TRAPP BD. (2001). Transsected neurites, apoptotic neurons and reduced inflammation in cortical multiple sclerosis lesions. Ann. Neurol, 50: 389-400.
    • (2001) Ann. Neurol , vol.50 , pp. 389-400
    • PETERSON, J.W.1    BO, L.2    MORK, S.3    CHANG, A.4    TRAPP, B.D.5
  • 34
    • 27644535269 scopus 로고    scopus 로고
    • Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis
    • POMEROY IM, MATTHEWS PM, FRANK JA, JORDAN EK, ESIRI MM. (2005). Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis. Brain, 128: 2713-2721.
    • (2005) Brain , vol.128 , pp. 2713-2721
    • POMEROY, I.M.1    MATTHEWS, P.M.2    FRANK, J.A.3    JORDAN, E.K.4    ESIRI, M.M.5
  • 35
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • SERAFINI B, ROSICARELLI B, MAGLIOZZI R, STIGLIANO E, ALOISI F. (2004). Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol, 14: 164-174.
    • (2004) Brain Pathol , vol.14 , pp. 164-174
    • SERAFINI, B.1    ROSICARELLI, B.2    MAGLIOZZI, R.3    STIGLIANO, E.4    ALOISI, F.5
  • 36
    • 18744394057 scopus 로고    scopus 로고
    • Tissue preconditioning may explain concentric lesions in Balo's type of multiple sclerosis
    • STADELMANN C, LUDWIN S, TABIRA T et al. (2005). Tissue preconditioning may explain concentric lesions in Balo's type of multiple sclerosis. Brain 128: 979-987
    • (2005) Brain , vol.128 , pp. 979-987
    • STADELMANN, C.1    LUDWIN, S.2    TABIRA, T.3
  • 37
    • 33845371444 scopus 로고    scopus 로고
    • Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatability complex (MHC) haplotype-related
    • STORCH MK, BAUER J, LININGTON C, OLSSON T, WEISSERT R, LASSMANN H. (2006). Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatability complex (MHC) haplotype-related. J Neuropathol Exp Neurol, 65: 1137-1142.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 1137-1142
    • STORCH, M.K.1    BAUER, J.2    LININGTON, C.3    OLSSON, T.4    WEISSERT, R.5    LASSMANN, H.6
  • 38
    • 0031688565 scopus 로고    scopus 로고
    • Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology
    • STORCH MK, STEFFERL A, BREHM U et al. (1998b). Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Brain Pathol, 8: 681-694.
    • (1998) Brain Pathol , vol.8 , pp. 681-694
    • STORCH, M.K.1    STEFFERL, A.2    BREHM, U.3
  • 39
    • 0035877190 scopus 로고    scopus 로고
    • + T cells are encephalitogenic and produce severe disease in C57Bl/6 mice
    • + T cells are encephalitogenic and produce severe disease in C57Bl/6 mice. J Immunol, 166: 7579-7587.
    • (2001) J Immunol , vol.166 , pp. 7579-7587
    • SUN, D.1    WHITAKER, J.N.2    HUANG, Z.3
  • 40
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • TRAPP BD, PETERSON J, RANSOHOFF RM et al. (1998). Axonal transection in the lesions of multiple sclerosis. N-Engl-J-Med, 338: 278-285.
    • (1998) N-Engl-J-Med , vol.338 , pp. 278-285
    • TRAPP, B.D.1    PETERSON, J.2    RANSOHOFF, R.M.3


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