-
1
-
-
77956903741
-
Tryptophan Synthase
-
Boyer, P. D, Ed, 3rd ed, pp, Academic Press, New York
-
Yanofsky, C., and Crawford, I. P. (1972) Tryptophan Synthase, in The Enzyme (Boyer, P. D., Ed.) 3rd ed., pp 1-31, Academic Press, New York.
-
(1972)
The Enzyme
, pp. 1-31
-
-
Yanofsky, C.1
Crawford, I.P.2
-
2
-
-
0018657645
-
Tryptophan synthase: Structure, function, and subunit interaction
-
Miles, E. W. (1979) Tryptophan synthase: Structure, function, and subunit interaction, Adv. Enzymol. Relat. Areas Mol. Biol. 49, 127-186.
-
(1979)
Adv. Enzymol. Relat. Areas Mol. Biol
, vol.49
, pp. 127-186
-
-
Miles, E.W.1
-
3
-
-
0026086276
-
Structural basis for catalysis by tryptophan synthase
-
Miles, E. W. (1991) Structural basis for catalysis by tryptophan synthase, Adv. Enzymol. Relat. Areas Mol. Biol. 64, 93.
-
(1991)
Adv. Enzymol. Relat. Areas Mol. Biol
, vol.64
, pp. 93
-
-
Miles, E.W.1
-
4
-
-
0029204814
-
Tryptophan synthase. Structure, function, and protein engineering
-
Miles, E. W. (1995) Tryptophan synthase. Structure, function, and protein engineering, Subcell. Biochem. 24, 207-254.
-
(1995)
Subcell. Biochem
, vol.24
, pp. 207-254
-
-
Miles, E.W.1
-
5
-
-
0033617187
-
The molecular basis of substrate channeling
-
Miles, E. W., Rhee, S., and Davies, D. R. (1999) The molecular basis of substrate channeling, J. Biol. Chem. 274, 12193-12196.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 12193-12196
-
-
Miles, E.W.1
Rhee, S.2
Davies, D.R.3
-
6
-
-
0031028212
-
Protein architecture, dynamics and allostery in tryptophan synthase channeling
-
Pan, P., Woehl, E., and Dunn, M. F. (1997) Protein architecture, dynamics and allostery in tryptophan synthase channeling, Trends Biochem. Sci. 22, 22-27.
-
(1997)
Trends Biochem. Sci
, vol.22
, pp. 22-27
-
-
Pan, P.1
Woehl, E.2
Dunn, M.F.3
-
8
-
-
0025006579
-
The tryptophan synthase bienzyme complex transfers indole between the α- and β-sites via a 25-30 Å long tunnel
-
Dunn, M. F., Aguilar, V., Brzovic, P., Drewe, W. F., Jr., Houben, K. F., Leja, C. A., and Roy, M. (1990) The tryptophan synthase bienzyme complex transfers indole between the α- and β-sites via a 25-30 Å long tunnel, Biochemistry 29, 8598-8607.
-
(1990)
Biochemistry
, vol.29
, pp. 8598-8607
-
-
Dunn, M.F.1
Aguilar, V.2
Brzovic, P.3
Drewe Jr., W.F.4
Houben, K.F.5
Leja, C.A.6
Roy, M.7
-
9
-
-
0026764475
-
Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex
-
Brzovic, P. S., Ngo, K., and Dunn, M. F. (1992) Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex, Biochemistry 31, 3831-3839.
-
(1992)
Biochemistry
, vol.31
, pp. 3831-3839
-
-
Brzovic, P.S.1
Ngo, K.2
Dunn, M.F.3
-
10
-
-
0026715868
-
Evidence that mutations in a loop region of the α-subunit inhibit the transition from an open to a closed conformation in the tryptophan synthase bienzyme complex
-
Brzovic, P. S., Sawa, Y., Hyde, C. C., Miles, E. W., and Dunn, M. F. (1992) Evidence that mutations in a loop region of the α-subunit inhibit the transition from an open to a closed conformation in the tryptophan synthase bienzyme complex, J. Biol. Chem. 267, 13028-13038.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 13028-13038
-
-
Brzovic, P.S.1
Sawa, Y.2
Hyde, C.C.3
Miles, E.W.4
Dunn, M.F.5
-
11
-
-
0027440693
-
Characterization of the functional role of a flexible loop in the α-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis
-
Brzovic, P. S., Hyde, C. C., Miles, E. W., and Dunn, M. F. (1993) Characterization of the functional role of a flexible loop in the α-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis, Biochemistry 32, 10404-10413.
-
(1993)
Biochemistry
, vol.32
, pp. 10404-10413
-
-
Brzovic, P.S.1
Hyde, C.C.2
Miles, E.W.3
Dunn, M.F.4
-
12
-
-
0028988975
-
Allosteric linkages between β-site covalent transformations and α-site activation and deactivation in the tryptophan synthase bienzyme complex
-
Leja, C. A., Woehl, E. U., and Dunn, M. F. (1995) Allosteric linkages between β-site covalent transformations and α-site activation and deactivation in the tryptophan synthase bienzyme complex, Biochemistry 34, 6552-6561.
-
(1995)
Biochemistry
, vol.34
, pp. 6552-6561
-
-
Leja, C.A.1
Woehl, E.U.2
Dunn, M.F.3
-
13
-
-
0025916089
-
Serine modulates substrate channeling in tryptophan synthase-A novel intersubunit triggering mechanism
-
Anderson, K. S., Miles, E. W., and Johnson, K. A. (1991) Serine modulates substrate channeling in tryptophan synthase-A novel intersubunit triggering mechanism, J. Biol. Chem. 266, 8020-8033.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 8020-8033
-
-
Anderson, K.S.1
Miles, E.W.2
Johnson, K.A.3
-
14
-
-
0033151768
-
Mechanisms of monovalent cation action in enzyme catalysis: The first stage of the tryptophan synthase β-reaction
-
Woehl, E., and Dunn, M. F. (1999) Mechanisms of monovalent cation action in enzyme catalysis: The first stage of the tryptophan synthase β-reaction, Biochemistry 38, 7118-7130.
-
(1999)
Biochemistry
, vol.38
, pp. 7118-7130
-
-
Woehl, E.1
Dunn, M.F.2
-
15
-
-
0033152545
-
Mechanisms of monovalent cation action in enzyme catalysis: The tryptophan synthase α-, β-, and αβ-reactions
-
Woehl, E., and Dunn, M. F. (1999) Mechanisms of monovalent cation action in enzyme catalysis: The tryptophan synthase α-, β-, and αβ-reactions, Biochemistry 38, 7131-7141.
-
(1999)
Biochemistry
, vol.38
, pp. 7131-7141
-
-
Woehl, E.1
Dunn, M.F.2
-
16
-
-
0035957229
-
Investigation of allosteric linkages in the regulation of tryptophan synthase: The roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics
-
Weber-Ban, E., Hur, O., Bagwell, C., Banik, U., Yang, L. H., Miles, E. W., and Dunn, M. F. (2001) Investigation of allosteric linkages in the regulation of tryptophan synthase: The roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics, Biochemistry 40, 3497-3511.
-
(2001)
Biochemistry
, vol.40
, pp. 3497-3511
-
-
Weber-Ban, E.1
Hur, O.2
Bagwell, C.3
Banik, U.4
Yang, L.H.5
Miles, E.W.6
Dunn, M.F.7
-
17
-
-
0037031265
-
+-activated tryptophan synthase bienzyme complex
-
+-activated tryptophan synthase bienzyme complex, Biochemistry 41, 9982-9990.
-
(2002)
Biochemistry
, vol.41
, pp. 9982-9990
-
-
Harris, R.M.1
Dunn, M.F.2
-
18
-
-
24044547672
-
On the structural basis of the catalytic mechanism and the regulation of the α subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes
-
Kulik, V., Hartmann, E., Weyand, M., Frey, M., Gierl, A., Niks, D., Dunn, M. F., and Schlichting, I. (2005) On the structural basis of the catalytic mechanism and the regulation of the α subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes, J. Mol. Biol. 352, 608-620.
-
(2005)
J. Mol. Biol
, vol.352
, pp. 608-620
-
-
Kulik, V.1
Hartmann, E.2
Weyand, M.3
Frey, M.4
Gierl, A.5
Niks, D.6
Dunn, M.F.7
Schlichting, I.8
-
20
-
-
29344444790
-
Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex
-
Harris, R. M., Ngo, H., and Dunn, M. F. (2005) Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex, Biochemistry 44, 16886-16895.
-
(2005)
Biochemistry
, vol.44
, pp. 16886-16895
-
-
Harris, R.M.1
Ngo, H.2
Dunn, M.F.3
-
21
-
-
0029978425
-
β-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex
-
Pan, P., and Dunn, M. F. (1996) β-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex, Biochemistry 35, 5002-5013.
-
(1996)
Biochemistry
, vol.35
, pp. 5002-5013
-
-
Pan, P.1
Dunn, M.F.2
-
22
-
-
0033613244
-
Crystallographic studies of phosphonate-based α-reaction transition-state analogues complexed to tryptophan synthase
-
Sachpatzidis, A., Dealwis, C., Lubetsky, J. B., Liang, P. H., Anderson, K. S., and Lolis, E. (1999) Crystallographic studies of phosphonate-based α-reaction transition-state analogues complexed to tryptophan synthase, Biochemistry 38, 12665-12674.
-
(1999)
Biochemistry
, vol.38
, pp. 12665-12674
-
-
Sachpatzidis, A.1
Dealwis, C.2
Lubetsky, J.B.3
Liang, P.H.4
Anderson, K.S.5
Lolis, E.6
-
23
-
-
0036882159
-
On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase
-
Kulik, V., Weyand, M., Seidel, R., Niks, D., Arac, D., Dunn, M. F., and Schlichting, I. (2002) On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase, J. Mol. Biol. 324, 677-690.
-
(2002)
J. Mol. Biol
, vol.324
, pp. 677-690
-
-
Kulik, V.1
Weyand, M.2
Seidel, R.3
Niks, D.4
Arac, D.5
Dunn, M.F.6
Schlichting, I.7
-
24
-
-
0037155812
-
Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase
-
Weyand, M., Schlichting, I., Marabotti, A., and Mozzarelli, A. (2002) Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase, J. Biol. Chem. 277, 10647-10652.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 10647-10652
-
-
Weyand, M.1
Schlichting, I.2
Marabotti, A.3
Mozzarelli, A.4
-
25
-
-
0016813648
-
Circular dichroism and fluorescence studies on the binding of ligands to the α subunit of tryptophan synthase
-
Heyn, M. P., and Weischet, W. O. (1975) Circular dichroism and fluorescence studies on the binding of ligands to the α subunit of tryptophan synthase, Biochemistry 14, 2962-2968.
-
(1975)
Biochemistry
, vol.14
, pp. 2962-2968
-
-
Heyn, M.P.1
Weischet, W.O.2
-
26
-
-
0032554651
-
Loop closure and intersubunit communication in tryptophan synthase
-
Schneider, T. R., Gerhardt, E., Lee, M., Liang, P. H., Anderson, K. S., and Schlichting, I. (1998) Loop closure and intersubunit communication in tryptophan synthase, Biochemistry 37, 5394-5406.
-
(1998)
Biochemistry
, vol.37
, pp. 5394-5406
-
-
Schneider, T.R.1
Gerhardt, E.2
Lee, M.3
Liang, P.H.4
Anderson, K.S.5
Schlichting, I.6
-
27
-
-
0035947566
-
Allosteric communication of tryptophan synthase. Functional and regulatory properties of the βS178P mutant
-
Marabotti, A., De, B. D., Tramonti, A., Bettati, S., and Mozzarelli, A. (2001) Allosteric communication of tryptophan synthase. Functional and regulatory properties of the βS178P mutant, J. Biol. Chem. 276, 17747-17753.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 17747-17753
-
-
Marabotti, A.1
De, B.D.2
Tramonti, A.3
Bettati, S.4
Mozzarelli, A.5
-
28
-
-
0015951899
-
Activated intermediate analog: Use of phosphoglycolohydroxamate as a stable analog of a transiently occurring dihydroxyacetone phosphate-derived enolate in enzymatic catalysis
-
Collins, K. D. (1974) Activated intermediate analog: Use of phosphoglycolohydroxamate as a stable analog of a transiently occurring dihydroxyacetone phosphate-derived enolate in enzymatic catalysis, J. Biol. Chem. 249, 136-142.
-
(1974)
J. Biol. Chem
, vol.249
, pp. 136-142
-
-
Collins, K.D.1
-
29
-
-
0025331920
-
Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-Å resolution: Implications for catalysis
-
Lolis, E., and Petsko, G. A. (1990) Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-Å resolution: Implications for catalysis, Biochemistry 29, 6619-6625.
-
(1990)
Biochemistry
, vol.29
, pp. 6619-6625
-
-
Lolis, E.1
Petsko, G.A.2
-
30
-
-
34347327186
-
Allosteric regulation of tryptophan synthase channeling: The internal aldimine probed by trans-3-indole-3′-acrylate binding
-
Casino, P., Niks, D., Ngo, H., Pan, P., Brzovic, P., Blumenstein, L., Barends, T. R., Schlichting, I., and Dunn, M. F. (2007) Allosteric regulation of tryptophan synthase channeling: The internal aldimine probed by trans-3-indole-3′-acrylate binding, Biochemistry 46, 7728-7739.
-
(2007)
Biochemistry
, vol.46
, pp. 7728-7739
-
-
Casino, P.1
Niks, D.2
Ngo, H.3
Pan, P.4
Brzovic, P.5
Blumenstein, L.6
Barends, T.R.7
Schlichting, I.8
Dunn, M.F.9
-
31
-
-
34347366323
-
Allosteric regulation of substrate channeling in tryptophan synthase: Modulation of the L-serine reaction in stage I of the β-reaction by α-site ligands
-
Ngo, H., Kimmich, N., Harris, R., Niks, D., Blumenstein, L., Kulik, V., Barends, T. R., Schlichting, I., and Dunn, M. F. (2007) Allosteric regulation of substrate channeling in tryptophan synthase: Modulation of the L-serine reaction in stage I of the β-reaction by α-site ligands, Biochemistry 46, 7740-7753.
-
(2007)
Biochemistry
, vol.46
, pp. 7740-7753
-
-
Ngo, H.1
Kimmich, N.2
Harris, R.3
Niks, D.4
Blumenstein, L.5
Kulik, V.6
Barends, T.R.7
Schlichting, I.8
Dunn, M.F.9
-
33
-
-
0023072042
-
Tryptophan synthase from Escherichia coli and Salmonella typhimurium
-
Miles, E. W., Bauerle, R., and Ahmed, S. A. (1987) Tryptophan synthase from Escherichia coli and Salmonella typhimurium, Methods Enzymol. 142, 398-414.
-
(1987)
Methods Enzymol
, vol.142
, pp. 398-414
-
-
Miles, E.W.1
Bauerle, R.2
Ahmed, S.A.3
-
34
-
-
0024522515
-
The β-subunit of tryptophan synthase: Clarification of the roles of histidine-86, lysine-87, arginine-148, cysteine-170, and cysteine-230
-
Miles, E. W., Kawasaki, H., Ahmed, S. A., Morita, H., Morita, H., and Nagata, S. (1989) The β-subunit of tryptophan synthase: Clarification of the roles of histidine-86, lysine-87, arginine-148, cysteine-170, and cysteine-230, J. Biol. Chem. 264, 6280-6287.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 6280-6287
-
-
Miles, E.W.1
Kawasaki, H.2
Ahmed, S.A.3
Morita, H.4
Morita, H.5
Nagata, S.6
-
36
-
-
0032478094
-
Mutations in the contact region between the α and β subunits of tryptophan synthase alter subunit interaction and intersubunit communication
-
Rowlett, R., Yang, L. H., Ahmed, S. A., McPhie, P., Jhee, K. H., and Miles, E. W. (1998) Mutations in the contact region between the α and β subunits of tryptophan synthase alter subunit interaction and intersubunit communication, Biochemistry 37, 2961-2968.
-
(1998)
Biochemistry
, vol.37
, pp. 2961-2968
-
-
Rowlett, R.1
Yang, L.H.2
Ahmed, S.A.3
McPhie, P.4
Jhee, K.H.5
Miles, E.W.6
-
37
-
-
33947349367
-
Aliphatic hydroxylammonium salts and hydroxamic acids with halogen substituents
-
Jones, W. L., and Werner, F. L. (1916) Aliphatic hydroxylammonium salts and hydroxamic acids with halogen substituents, J. Am. Chem. Soc. 38, 413-422.
-
(1916)
J. Am. Chem. Soc
, vol.38
, pp. 413-422
-
-
Jones, W.L.1
Werner, F.L.2
-
38
-
-
0027465014
-
Phosphorothioate and phosphoramide analogs of dihydroxyacetone phosphate
-
Duncan, R., and Drueckhammer, D. G. (1993) Phosphorothioate and phosphoramide analogs of dihydroxyacetone phosphate, Tetrahedron Lett. 34, 1733-1736.
-
(1993)
Tetrahedron Lett
, vol.34
, pp. 1733-1736
-
-
Duncan, R.1
Drueckhammer, D.G.2
-
39
-
-
0027879008
-
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
-
Kabsch, W. (1993) Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants, J. Appl. Crystallogr. 26, 795-800.
-
(1993)
J. Appl. Crystallogr
, vol.26
, pp. 795-800
-
-
Kabsch, W.1
-
40
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination, Acta Crystallogr. D54, 905-921.
-
(1998)
Acta Crystallogr
, vol.D54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
Read, R.J.11
Rice, L.M.12
Simonson, T.13
Warren, G.L.14
-
41
-
-
84889120137
-
Improved methods for building protein models in electron-density maps and the location of errors in these models
-
Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Improved methods for building protein models in electron-density maps and the location of errors in these models, Acta Crystallogr. A47, 110-119.
-
(1991)
Acta Crystallogr
, vol.A47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
42
-
-
0032790081
-
XtalView Xfit: A versatile program for manipulating atomic coordinates and electron density
-
McRee, D. E. (1999) XtalView Xfit: A versatile program for manipulating atomic coordinates and electron density, J. Struct. Biol. 125, 156-165.
-
(1999)
J. Struct. Biol
, vol.125
, pp. 156-165
-
-
McRee, D.E.1
-
43
-
-
0022344850
-
Detection and identification of intermediates in the reaction of L-serine with Escherichia coli tryptophan synthase via rapid-scanning ultraviolet-visible spectroscopy
-
Drewe, W. F., Jr., and Dunn, M. F. (1985) Detection and identification of intermediates in the reaction of L-serine with Escherichia coli tryptophan synthase via rapid-scanning ultraviolet-visible spectroscopy, Biochemistry 24, 3977-3987.
-
(1985)
Biochemistry
, vol.24
, pp. 3977-3987
-
-
Drewe Jr., W.F.1
Dunn, M.F.2
-
44
-
-
0025216256
-
Allosteric effects acting over a distance of 20-25 Å in the Escherichia coli tryptophan synthase bienzyme complex increase ligand affinity and cause redistribution of covalent intermediates
-
Houben, K. F., and Dunn, M. F. (1990) Allosteric effects acting over a distance of 20-25 Å in the Escherichia coli tryptophan synthase bienzyme complex increase ligand affinity and cause redistribution of covalent intermediates, Biochemistry 29, 2421-2429.
-
(1990)
Biochemistry
, vol.29
, pp. 2421-2429
-
-
Houben, K.F.1
Dunn, M.F.2
-
45
-
-
0014559851
-
Active chemical state of D-glyceraldehyde 3-phosphate in its reactions with D-glyceraldehyde 3-phosphate dehydrogenase, aldolase and triose phosphate isomerase
-
Trentham, D. R., McMurray, C. H., and Pogson, C. I. (1969) Active chemical state of D-glyceraldehyde 3-phosphate in its reactions with D-glyceraldehyde 3-phosphate dehydrogenase, aldolase and triose phosphate isomerase, Biochem. J. 114, 19.
-
(1969)
Biochem. J
, vol.114
, pp. 19
-
-
Trentham, D.R.1
McMurray, C.H.2
Pogson, C.I.3
-
46
-
-
0023782859
-
Stereoelectronic control of bond formation in Escherichia coli tryptophan synthase: Substrate specificity and enzymatic synthesis of the novel amino acid dihydroisotryptophan
-
Roy, M., Keblawi, S., and Dunn, M. F. (1988) Stereoelectronic control of bond formation in Escherichia coli tryptophan synthase: Substrate specificity and enzymatic synthesis of the novel amino acid dihydroisotryptophan, Biochemistry 27, 6698-6704.
-
(1988)
Biochemistry
, vol.27
, pp. 6698-6704
-
-
Roy, M.1
Keblawi, S.2
Dunn, M.F.3
-
47
-
-
0032502775
-
2 complex reveals the correct orientation of active site αGlu49
-
2 complex reveals the correct orientation of active site αGlu49, J. Biol. Chem. 273, 8553-8555.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 8553-8555
-
-
Rhee, S.1
Miles, E.W.2
Davies, D.R.3
-
48
-
-
0033554845
-
Crystal structure of wildtype tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate
-
Weyand, M., and Schlichting, I. (1999) Crystal structure of wildtype tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate, Biochemistry 38, 16469-16480.
-
(1999)
Biochemistry
, vol.38
, pp. 16469-16480
-
-
Weyand, M.1
Schlichting, I.2
-
49
-
-
0030800147
-
2 complex with ligands bound to the active sites of the α- and β-subunits reveal ligand-induced conformational changes
-
2 complex with ligands bound to the active sites of the α- and β-subunits reveal ligand-induced conformational changes, Biochemistry 36, 7664-7680.
-
(1997)
Biochemistry
, vol.36
, pp. 7664-7680
-
-
Rhee, S.1
Parris, K.D.2
Hyde, C.C.3
Ahmed, S.A.4
Miles, E.W.5
Davies, D.R.6
-
50
-
-
0035954399
-
βD305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity
-
Ferrari, D., Yang, L. H., Miles, E. W., and Dunn, M. F. (2001) βD305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity, Biochemistry 40, 7421-7432.
-
(2001)
Biochemistry
, vol.40
, pp. 7421-7432
-
-
Ferrari, D.1
Yang, L.H.2
Miles, E.W.3
Dunn, M.F.4
-
52
-
-
0013800421
-
The interaction of a naphthalene dye with apomyoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites
-
Stryer, L. (1965) The interaction of a naphthalene dye with apomyoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites, J. Mol. Biol. 13, 482-495.
-
(1965)
J. Mol. Biol
, vol.13
, pp. 482-495
-
-
Stryer, L.1
-
53
-
-
0020674663
-
The mechanism of binding of L-serine to tryptophan synthase from Escherichia coli
-
Lane, A. N., and Kirschner, K. (1983) The mechanism of binding of L-serine to tryptophan synthase from Escherichia coli, Eur. J. Biochem. 129, 561-570.
-
(1983)
Eur. J. Biochem
, vol.129
, pp. 561-570
-
-
Lane, A.N.1
Kirschner, K.2
-
54
-
-
0037155842
-
Crystal structure of the β Ser178→ Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme
-
Weyand, M., Schlichting, I., Herde, P., Marabotti, A., and Mozzarelli, A. (2002) Crystal structure of the β Ser178→ Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme, J. Biol. Chem. 277, 10653-10660.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 10653-10660
-
-
Weyand, M.1
Schlichting, I.2
Herde, P.3
Marabotti, A.4
Mozzarelli, A.5
-
55
-
-
0038339376
-
Allosteric communication in the tryptophan synthase bienzyme complex: Roles of the β-subunit aspartate 305-arginine 141 salt bridge
-
Ferrari, D., Niks, D., Yang, L. H., Miles, E. W., and Dunn, M. F. (2003) Allosteric communication in the tryptophan synthase bienzyme complex: Roles of the β-subunit aspartate 305-arginine 141 salt bridge, Biochemistry 42, 7807-7818.
-
(2003)
Biochemistry
, vol.42
, pp. 7807-7818
-
-
Ferrari, D.1
Niks, D.2
Yang, L.H.3
Miles, E.W.4
Dunn, M.F.5
-
56
-
-
0025980188
-
Reciprocal communication between the lyase and synthase active-sites of the tryptophan synthase bienzyme complex
-
Kirschner, K., Lane, A. N., and Strasser, A. W. M. (1991) Reciprocal communication between the lyase and synthase active-sites of the tryptophan synthase bienzyme complex, Biochemistry 30, 472-478.
-
(1991)
Biochemistry
, vol.30
, pp. 472-478
-
-
Kirschner, K.1
Lane, A.N.2
Strasser, A.W.M.3
-
57
-
-
0025975619
-
Mechanism of the physiological reaction catalyzed by tryptophan synthase from Escherichia coli
-
Lane, A. N., and Kirschner, K. (1991) Mechanism of the physiological reaction catalyzed by tryptophan synthase from Escherichia coli, Biochemistry 30, 479-484.
-
(1991)
Biochemistry
, vol.30
, pp. 479-484
-
-
Lane, A.N.1
Kirschner, K.2
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