Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex

Biochemistry

Volumn 44, Issue 51, 2005, Pages 16886-16895

  Harris, Rodney M ^a   Ngo, Huu ^b   Dunn, Michael F ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; COMPLEXATION; ENZYME KINETICS; PHOSPHATES; SUBSTRATES;

BIENZYME COMPLEXES; LIGANDS; SUBSTRATE CHANNELING; SYNREGISTIC EFFECTS;

ENZYMES;

BENZENESULFONIC ACID DERIVATIVE; BENZIMIDAZOLE; DEHYDROALANINE; INDOLE DERIVATIVE; LIGAND; N (4 TRIFLUOROMETHOXYBENZENESULFONYL) 2 AMINO 1 ETHYL PHOSPHATE; QUINONE DERIVATIVE; SCHIFF BASE; TRYPTOPHAN SYNTHASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ALPHA CHAIN; ARTICLE; BETA CHAIN; BINDING AFFINITY; DISSOCIATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; PRIORITY JOURNAL;

ALANINE; ALLOSTERIC REGULATION; BACTERIA; BENZIMIDAZOLES; CATALYTIC DOMAIN; GLYCEROPHOSPHATES; INDOLES; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; SPECTROPHOTOMETRY; TRYPTOPHAN; TRYPTOPHAN SYNTHASE;

EID: 29344444790     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0516881     Document Type: Article

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