Mutations in the contact region between the α and β subunits of tryptophan synthase alter subunit interaction and intersubunit communication

Biochemistry

Volumn 37, Issue 9, 1998, Pages 2961-2968

  Rowlett, Roger ^a,c   Yang, Li Hong ^a,d   Ahmed, S Ashraf ^a,e   McPhie, Peter ^a   Jhee, Kwang Hwan ^a   Miles, Edith Wilson ^a,b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Center for Language and Brain   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^e UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE; TRYPTOPHAN SYNTHASE;

ALPHA CHAIN; ARTICLE; BETA CHAIN; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; ENZYME ASSAY; ENZYME CONFORMATION; ENZYME SPECIFICITY; LIGAND BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SALMONELLA TYPHIMURIUM;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; KINETICS; LIGANDS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRYPTOPHAN SYNTHASE;

EID: 0032478094     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972286z     Document Type: Article

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