Retrovirus-mediated CXCR4-siRNA can inhibit the invasion of prostate carcinoma in vitro

Chinese Journal of Cancer Research

Volumn 19, Issue 2, 2007, Pages 82-88

  Du, Yue Feng ^a   Shi, Ying ^a   Xing, Yi Fei ^a   Xiao, Ya Jun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CXCR4; Invasion; Metastasis; RNA interference

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; RETROVIRUS VECTOR; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION; GENETIC RECOMBINATION; GENETIC TRANSFECTION; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; POLYMERASE CHAIN REACTION; PROSTATE CARCINOMA; PROTEIN EXPRESSION; VIRAL GENE THERAPY;

EID: 34347221518     PISSN: 10009604     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11670-007-0082-9     Document Type: Article

References (17)

1. Zlontnic A, Yoshie O. Chemokines: a new classification system and their role in immunity[J]. Immunity 2000; 12:121-7.
2. Libura J, Drukala J, Majka M, el al. CXCR4-SDF-1 signaling is active inrhabdomyosarcoma cell and regulates locomotion, chemotaxis, and adhesion[J]. Blood 2002; 100: 2597-606.
3. Schrader AJ, Lechner O, Templin M, el al. CXCR4/ CXc112 expression and signaling in kidney cancer[J]. Br J Cancer 2002; 86: 1250-6.
4. Bertolini F, Dell's Agnola C, Mancuso P, et al. CXCR4 neutralization, a novel therapeutic approach for non- Hodgkin's lymphoma[J]. Cancer Res 2002; 62: 3112.
5. Kijiama T, Maulik G, ma PC, et al. Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cells[J]. Cancer Res 2002; 62: 6304-11.
6. Ui-Teik, Naito Y, Takahashi F, et al. Guidelines for the selection of highly effectively siRNA sequence for mammalian and chick RNA interference[J]. Nucleic Acids Res 2004; 32: 936-48.
7. Ohira S, Sasaki M, Harada K, et al. Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor -{alpha} and Stromal-Derived Factor-1 Released in Stroma[J]. Am J Pathol 2006; 168: 1155-68.
8. Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis[J]. Nature 2001; 410: 50.
9. Kortesidis A, Zannettino A, Isenmann S, et al. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells[J]. Blood 2005; 105: 3793-801.
10. Katayama A, Ogino T, Bandoh N, et al. Expression of CXCR4 and its down-regulation by IFN-gamma in head and neck squamous cell carcinoma[J]. Clin Cancer Res 2005; 11: 2937-46
11. Tamamura H, Tsutsumi H, Fujii N. The chemokine receptor CXCR4 as a therapeutic target for several diseases[J]. Mini Rev Med Chem 2006; 6: 989-95.
12. Ratajczak MZ, Zuba-Surma E, Kucia M, et al. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis[J]. Leukemia 2006; 20: 1915-24.
13. Leung RK, Whittaker PA. RNA interference: from gene silencing to gene-specific therapeutics[J]. Pharmacol Ther 2005; 107: 222-39.
14. Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells[J]. Nature 2001; 411: 494-8
15. Bantounas I, Phylactou LA, Uney JB. RNA interference and the use of small interfering RNA to study gene function in mammalian systems[J]. J Mol Endocrinol 2004; 33: 545-57
16. Xu D, McCarty D, Fernandes A, et al. Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno- -associated virus vector[J]. Mol Ther 2005; 11: 523-30
17. Hideki M, Akio M, Jun T, et al. Interaction of ligand-receptor system between stromal-cell-derived factor-1 and CXC chemokine receptor 4 in human prostate cancer: a possible predictor of metastasis[J]. Bio Biophy Res 2004; 320: 656-63.