Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line

Clinical Cancer Research

Volumn 3, Issue 5, 1997, Pages 685-696

  Waanders, Gary A ^a,d   Rimoldi, Donata ^a,b   Liénard, Danielle ^a   Carrel, Stefan ^a   Lejeune, Ferdy ^b   Dietrich, Pierre Yves ^c   Cerottini, Jean Charles ^a   Romero, Pedro ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d DiagnoCure Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TUMOR ANTIGEN;

ANTIGEN SPECIFICITY; ARTICLE; CELL CULTURE; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOTHERAPY; MELANOMA; PRIORITY JOURNAL; SKIN BIOPSY; SUPPRESSOR CELL;

AGED; AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; BASE SEQUENCE; BIOPSY; CELLS, CULTURED; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; HYPERSENSITIVITY, DELAYED; IMMUNOTHERAPY; MALE; MELANOMA; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SKIN; SKIN NEOPLASMS; T-LYMPHOCYTES, CYTOTOXIC; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030998998     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. De Plaen, E., Arden, K., Traversari, C., Gaforio, J. J., Szikora, J. P., De Smet, C., Brasseur, F., van der Bruggen, P., Lethé, B., Lurquin, C., Brasseur, R., Chomez, P., de Backer, O., Cazenave, W., and Boon, T. Structure, chromosomal localization, and expression of 12 genes of the MAGE family. Immunogenetics, 40: 360-369, 1994.
2. Van den Eynde, B., Peeters, O., de Backer, O., Gaugler, B., Lucas, S., and Boon, T. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. J. Exp. Med., 182: 689-698, 1995.
3. Boel, P., Wildmann, C., Sensi, M. L., Brasseur, R., Renauld, J. C., Coulie, P., Boon, T., and van der Bruggen, P. BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. Immunity, 2: 167-175, 1995.
4. Wölfel, T., Van Pel, A., Brichard, V., Schneider, J., Seliger, B., Meyer zum Buschenfelde, K. H., and Boon, T. Two tyrosinase non-apeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur. J. Immunol., 24: 759-764, 1994.
5. Coulie, P. G., Brichard, V., Van Pel, A., Wölfel, T., Schneider, J., Traversari, C., Mattei, S., De Plaen, E., Lurquin, C., Szikora, J. P., Renauld, J. C., and Boon, T. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 180: 35-42, 1994.
6. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Rivoltini, L., Topalian, S. L., Miki, T., and Rosenberg, S. A. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. USA, 91: 3515-3519, 1994.
7. Cox, A. L., Skipper, J., Chen, Y., Henderson, R. A., Darrow, T. L., Shabanowitz, J., Engelhard, V. H., Hunt, D. F., and Slingluff, C. L., Jr. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science (Washington DC), 264: 716-719, 1994.
8. Wang, R. F., Robbins, P. F., Kawakami, Y., Kang, X. Q., and Rosenberg, S. A. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor infiltrating lymphocytes. J. Exp. Med., 181: 799-804, 1995.
9. Boon, T., Cerottini, J. C., Van den Eynde, B., van der Bruggen, P., and Van Pel, A. Tumor antigens recognized by T lymphocytes. Annu. Rev. Immunol., 12: 337-365, 1994.
10. Boon, T., Gajewski, T. F., and Coulie, P. G. From defined human tumor antigens to effective immunization? Immunol. Today, 16: 334-337, 1995.
11. Berd, D., Maguire, H. C., Jr., McCue, P., and Mastrangelo, M. J. Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients. J. Clin. Oncol., 8: 1858-1867, 1990.
12. Herr, W., Wölfel, T., Heike, M. Meyer zum Büschenfelde, K. H., and Knuth, A. Frequency analysis of tumor-reactive cytotoxic T lymphocytes in peripheral blood of a melanoma patient vaccinated with autologous tumor cells. Cancer lmmunol. Immunother., 39: 93-99, 1994.
13. Hoon, D. S. B., Yuzuki, D., Hayashida, M., and Morton, D. L. Melanoma patients immunized with melanoma cell vaccine induce antibody responses to recombinant MAGE-1 antigen. J. Immunol., 154: 730-737, 1995.
14. Lehmann, F., Marchand, M., Hainaut, P., Pouillart, P., Sastre, X., Ikeda, H., Boon, T., and Coulie, P. G. Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection. Eur. J. Immunol., 25: 340-347, 1995.
15. Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D., and Mulligan, R. C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA, 90: 3539-3543, 1993.
16. Bystryn, J. C., Oratz, R., Roses, D., Harris, M., Henn, M., and Lew, R. Relationship between immune response to melanoma vaccine immunization and clinical outcome in stage II malignant melanoma. Cancer (Phila.), 69: 1157-1164, 1992.
17. Schultz, N., Oratz, R., Chen, D., Zeleniuch-Jacquotte, A., Abeles, G., and Bystryn, J. C. Effect of DETOX as an adjuvant for melanoma vaccine. Vaccine, 13: 503-508, 1995.
18. Irvine, K. R., McCabe, B. J., Rosenberg, S. A., and Restifo, N. P. Synthetic oligonucleotide expressed by a recombinant vaccinia virus elicits therapeutic CTL. J. Immunol., 154: 4651-4657, 1995.
19. Chen, P. W., Wang, M., Bronte, V., Zhai, Y., Rosenberg, S. A., and Restifo, N. P. Therapeutic antitumor response after immunization with a recombinant adenovirus encoding a model tumor-associated antigen. J. Immunol., 156: 224-231, 1996.
20. Mukherji, B., Chakraborty, N. G., Yamasaki, S., Okino, T., Yamase, H., Sporn, J. R., Kurtzman, S. K., Ergin, M. T., Ozols, J., Meehan, J., and Mauri, F. Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells. Proc. Natl. Acad. Sci. USA, 92: 8078-8082, 1995.
21. Jaeger, E., Bernhard, H., Romero, P., Ringhoffer, M., Arand, M., Karbach, J., Ilsemann, C., Hagedorn, M., and Knuth, A. Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptides in vivo: implications for tumor vaccines with melanoma-associated antigens. Int. J. Cancer, 66: 162-169, 1996.
22. Waanders, G. A., Lees, R. K., Held, W., and MacDonald, H. R. Quantitation of endogenous mouse mammary tumor virus superantigen expression by lymphocyte subsets. Eur. J. Immunol., 25: 2632-2637, 1995.
23. Brasseur, F., Rimoldi, D., Liénard, D., Lethé, B., Carrel, S., Arienti, F., Suter, L., Vanwijck, R., Bourlond, A., Humblet, Y., Vacca, A., Conese, M., Lahaye, T., Degiovanni, G., Deraemaecker, R., Beauduin, M., Sastre, X., Salamon, E., Dréno, B., Jäger, E., Knuth, A., Chevreau, C., Suciu, S., Lachapelle, J. M., Pouillart, P., Parmiani, G., Lejeune, F., Cerottini, J. C., Boon, T., and Marchand, M. Expression of MAGE genes in primary and metastatic cutaneous melanoma. Int. J. Cancer, 63: 375-380, 1995.
24. Carrel, S., Doré, J-F., Ruiter, D. J., Prade, M., Lejeune, F. J., Kleeberg, U. R., Rümke, P., and Bröcker, E. V. The EORTC melanoma group exchange program: evaluation of a multicenter monoclonal antibody study. Int. J. Cancer, 48: 836-847, 1991.
25. Waanders, G. A., Lussow, A. R., and MacDonald, H. R. Skewed T cell receptor Vα repertoire among superantigen reactive murine T cells. Int. Immunol., 5: 55-61, 1993.
26. 35S)dATP. Methods Mol. Biol., 23: 191-197, 1993.
27. Pannetier, C., Even, J., and Kourilsky, P. T cell repertoire diversity and clona) expansions in normal and clinical samples. Immunol. Today, 16: 176-181, 1995.
28. Genevée, C., Diu, A., Nierat, J., Caignard, A., Dietrich, P. Y., Ferradini, L., Roman-Roman, S., Triebel, F., and Hercend, T. An experimentally validated panel of subfamily-specific oligonucleotide primers (Vα1-w29/Vβ1-w24) for the study of human T cell receptor variable gene segment usage by polymerase chain reaction. Eur. J. Immunol., 22: 1261-1269, 1992.
29. Romero, P., Pannetier, C., Herman, J., Jongeneel, C. V., Cerottini, J. C., and Coulie, P. G. Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1. J. Exp. Med., 182: 1019-1028, 1995.
30. - T lymphocytes: antigenic properties. J. Immunol., 150: 1147-1159, 1993.
31. Caignard, A., Guillard, M., Gaudin, C., Escudier, B., Triebel, F., and Dietrich, P. Y. In situ demonstration of renal cell carcinoma-specific T-cell clones. Int. J. Cancer, 66: 564-570, 1996.
32. Brichard, V. G., Warnier, G., Van Pel, A., Morlighem, G., Lucas, S., and Boon, T. Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815. Eur. J. Immunol., 25: 664-671, 1995.
33. Kalish, R. S., and Johnson, K. L. Enrichment and function of urushiol (poison ivy)-specific T lymphocytes in lesions of allergic contact dermatitis to urushiol. J. Immunol., 145: 3706-3713, 1990.
34. Posnett, D. N., Sinha, R., Kabak, S., and Russo, C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammopathy." J. Exp. Med., 179: 609-618, 1994.
35. Van den Eynde, B., Hainaut, P., Hérin, M., Knuth, A., Lemoine, C., Weynants, P., Van der Bruggen, P., Fauchet, R., and Boon, T. Presence on a human melanoma of multiple antigens recognized by autologous CTL. Int. J. Cancer, 44: 634-640, 1989.
36. + T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene. Proc. Natl. Acad. Sci. USA, 91: 9461-9465, 1994.
37. + T lymphocytes against human melanoma: evidence for a shared melanoma antigen presented by HLA-DR15. J. Immunol., 154: 772-779, 1995.
38. + melanoma-infiltrating lymphocytes. Eur. J. Immunol., 25: 2732-2736, 1995.