Why do so many cancer patients fail to respond to interferon therapy?

Journal of Interferon and Cytokine Research

Volumn 16, Issue 4, 1996, Pages 275-281

  Einhorn, Stefan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERFERON; INTERFERON ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON;

ANEMIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; CANCER IMMUNOTHERAPY; CANCER PATIENT; CARCINOID; CHILL; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; DRUG RESISTANCE; FATIGUE; FEVER; HAIRY CELL LEUKEMIA; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; KIDNEY CARCINOMA; LYMPHOMA; MULTIPLE MYELOMA; MYALGIA; NEUTROPENIA; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SUBCUTANEOUS DRUG ADMINISTRATION; THROMBOCYTOPENIA; TREATMENT FAILURE;

EID: 0029964303     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1996.16.275     Document Type: Review

References (4)

1. EINHORN, S., and STRANDER, H. (1993). Interferon treatment of human malignancies - a short review. Med. Oncol. Tumor Pharmacother. 10, 25-29.
2. GUTTERMAN, J. (1994). Cytokine therapeutics: lessons from interferon α. Proc. Natl. Acad. Sci. USA 91, 1198-1205.
3. CANTELL, K., PYHÄLÄ, L., and STRANDER, H. (1974). Circulating human Interferon after intramuscular injection into animals and man. J. Gen. Virol. 22, 453-458.
4. BOCCI, V., CARRARO, F., NALDINI, A., BORRELLI, E., BIAGI, G., GOTTI, G., and GIOMARELLI, P.P. (1990). Interferon levels in human pulmonary tumors are lower than plasma levels. J. Biol. Regul. Homeost. Agents 4, 153-156.