Activation mechanisms for the cystic fibrosis transmembrane conductance regulator protein involve direct binding of cAMP

Biochemical Journal

Volumn 405, Issue 1, 2007, Pages 181-189

  Pereira, Malcolm M C ^a   Parker, Jody ^a   Stratford, Fiona L L ^a   McPherson, Margaret ^a   Dormer, Robert L ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

cAMP; Cyclic nucleotide; Cystic fibrosis transmembrane conductance regulator; Ligand binding; Mutation; Protein secretion

Indexed keywords

ADENOSINETRIPHOSPHATE; LIGANDS; NUCLEOTIDES; PHOSPHORYLATION; PROTEINS; SYNTHESIS (CHEMICAL);

CYCLIC NUCLEOTIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; LIGAND BINDING; MUTATION; PROTEIN SECRETION;

BIOLOGICAL MEMBRANES;

CYCLIC AMP; CYCLIC NUCLEOTIDE; NUCLEOTIDE; NUCLEOTIDE BINDING PROTEIN; RADIOLIGAND; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRITIUM;

ARTICLE; BINDING AFFINITY; BINDING SITE; CYSTIC FIBROSIS; GENE MUTATION; LIGAND BINDING; MEMBRANE CONDUCTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REGULATORY MECHANISM;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBODIES; CYCLIC AMP; CYCLIC GMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RADIOLIGAND ASSAY; RECOMBINANT FUSION PROTEINS;

EID: 34347207546     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061879     Document Type: Article

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