-
1
-
-
0025931429
-
Nucleoside triphosphates are required to open the CFTR chloride channel
-
Anderson, M. P., H. A. Berger, D. R. Rich, R. J. Gregory, A. E. Smith, and M. J. Welsh. Nucleoside triphosphates are required to open the CFTR chloride channel. Cell 67: 775-784, 1991.
-
(1991)
Cell
, vol.67
, pp. 775-784
-
-
Anderson, M.P.1
Berger, H.A.2
Rich, D.R.3
Gregory, R.J.4
Smith, A.E.5
Welsh, M.J.6
-
2
-
-
0032489513
-
Direct activation of cystic fibrosis transmembrane conductance regulator channels by 8-cyclopentyl-1,3-dipropylxanthine (CPX) and 1,3-diallyl-8-cyclohexylxanthine (DAX)
-
Arispe, N., J. Ma, K. A. Jacobson, and H. B. Pollard. Direct activation of cystic fibrosis transmembrane conductance regulator channels by 8-cyclopentyl-1,3-dipropylxanthine (CPX) and 1,3-diallyl-8-cyclohexylxanthine (DAX). J. Biol. Chem. 273: 5727-5734, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5727-5734
-
-
Arispe, N.1
Ma, J.2
Jacobson, K.A.3
Pollard, H.B.4
-
3
-
-
0026077676
-
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel
-
Berger, H. A., M. P. Anderson, R. J. Gregory, S. Thompson, P. W. Howard, R. A. Mauer, R. Mulligan, A. E. Smith, and M. J. Welsh. Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. J. Clin. Invest. 88: 1422-1431, 1991.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1422-1431
-
-
Berger, H.A.1
Anderson, M.P.2
Gregory, R.J.3
Thompson, S.4
Howard, P.W.5
Mauer, R.A.6
Mulligan, R.7
Smith, A.E.8
Welsh, M.J.9
-
4
-
-
0025987020
-
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
-
Cheng, S. H., D. P. Rich, J. Marshall, R. J. Gregory, M. J. Welsh, and A. E. Smith. Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell 66: 1027-1036, 1991.
-
(1991)
Cell
, vol.66
, pp. 1027-1036
-
-
Cheng, S.H.1
Rich, D.P.2
Marshall, J.3
Gregory, R.J.4
Welsh, M.J.5
Smith, A.E.6
-
5
-
-
0030943895
-
8-Cyclopentyl-1,3-diproplyxanthine and other xanthines differentially bind to the first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator
-
Cohen, B. E., G. Lee, K. A. Jacobson, Y.-C. Kim, Z. Huang, E. J. Sorscher, and H. B. Pollard. 8-Cyclopentyl-1,3-diproplyxanthine and other xanthines differentially bind to the first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator. Biochemistry 36: 6455-6461, 1997.
-
(1997)
Biochemistry
, vol.36
, pp. 6455-6461
-
-
Cohen, B.E.1
Lee, G.2
Jacobson, K.A.3
Kim, Y.-C.4
Huang, Z.5
Sorscher, E.J.6
Pollard, H.B.7
-
6
-
-
0026620450
-
8-(4-Chlorophenyl)thio-cyclic AMP is a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA)
-
Connolly, B. J., P. B. Willits, B. H. Warrington, and K. J. Murray. 8-(4-Chlorophenyl)thio-cyclic AMP is a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA). Biochem. Pharmacol. 44: 2303-2306, 1992.
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 2303-2306
-
-
Connolly, B.J.1
Willits, P.B.2
Warrington, B.H.3
Murray, K.J.4
-
7
-
-
0025942250
-
Immunocytochemical localization of the cystic fibrosis gene product CFTR
-
Crawford, I., P. C. Maloney, P. L. Zeitlin, W. B. Guggino, S. C. Hyde, H. Turley, K. C. Gatter, A. Harris, and C. F. Higgins. Immunocytochemical localization of the cystic fibrosis gene product CFTR. Proc. Natl. Acad. Sci. USA 88: 9262-9366, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9262-9366
-
-
Crawford, I.1
Maloney, P.C.2
Zeitlin, P.L.3
Guggino, W.B.4
Hyde, S.C.5
Turley, H.6
Gatter, K.C.7
Harris, A.8
Higgins, C.F.9
-
8
-
-
0026781952
-
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
-
Denning, G. M., M. P. Anderson, J. F. Amara, J. Marshall, A. E. Smith, and M. J. Welsh. Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature 358: 761-764, 1992.
-
(1992)
Nature
, vol.358
, pp. 761-764
-
-
Denning, G.M.1
Anderson, M.P.2
Amara, J.F.3
Marshall, J.4
Smith, A.E.5
Welsh, M.J.6
-
9
-
-
0026337305
-
Chloride conductance expressed by ΔF508 and other mutant CFTRs in Xenopus oocytes
-
Drumm, M. L., D. J. Wilkinson, L. S. Smit, R. T. Worrell, T. V. Strong, R. A. Frizzell, D. C. Dawson, and F. S. Collins. Chloride conductance expressed by ΔF508 and other mutant CFTRs in Xenopus oocytes. Science 254: 1797-1799, 1991.
-
(1991)
Science
, vol.254
, pp. 1797-1799
-
-
Drumm, M.L.1
Wilkinson, D.J.2
Smit, L.S.3
Worrell, R.T.4
Strong, T.V.5
Frizzell, R.A.6
Dawson, D.C.7
Collins, F.S.8
-
10
-
-
0026611093
-
1-adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells
-
1-adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells. Proc. Natl. Acad. Sci. USA 89: 5562-5566, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5562-5566
-
-
Eidelman, O.1
Guay-Broder, C.2
Van Galen, P.J.M.3
Jacobson, K.A.4
Fox, C.5
Turner, R.J.6
Cabantchik, Z.I.7
Pollard, H.B.8
-
12
-
-
0027938084
-
Regulation of CFTR channel gating
-
Gadsby, D. C., and A. C. Nairn. Regulation of CFTR channel gating. Trends Biochem. Sci. 19: 513-518, 1994.
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 513-518
-
-
Gadsby, D.C.1
Nairn, A.C.2
-
13
-
-
0028247368
-
The substituted benzimidazolone NS004 is an opener of the cystic fibrosis chloride channel
-
Gribkoff, V., G. Champigny, P. Barbry, S. Dworetzky, N. Meanwell, and M. Lazdunski. The substituted benzimidazolone NS004 is an opener of the cystic fibrosis chloride channel. J. Biol. Chem. 269: 10983-10986, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10983-10986
-
-
Gribkoff, V.1
Champigny, G.2
Barbry, P.3
Dworetzky, S.4
Meanwell, N.5
Lazdunski, M.6
-
14
-
-
0029899053
-
ΔF508-CFTR channels: Kinetics, activation by forskolin, and potentiation by xanthines
-
Cell Physiol. 39
-
Haws, C. M., I. B. Nepomuceno, M. E. Krouse, H. Wakelee, T. Law, Y. Xia, H. Nguyen, and J. J. Wine. ΔF508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines. Am. J. Physiol. 270 (Cell Physiol. 39): C1544-C1555, 1996.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Haws, C.M.1
Nepomuceno, I.B.2
Krouse, M.E.3
Wakelee, H.4
Law, T.5
Xia, Y.6
Nguyen, H.7
Wine, J.J.8
-
16
-
-
0030773897
-
Potentiation of ΔF508 channel function by genistein binding to CFTR
-
Cell Physiol. 42
-
Hwang, T.-C., F. Wang, S. Zeltwanger, I. C.-H. Yang, and W. W. Reenstra. Potentiation of ΔF508 channel function by genistein binding to CFTR. Am. J. Physiol. 273 (Cell Physiol. 42): C988-C998, 1997.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Hwang, T.-C.1
Wang, F.2
Zeltwanger, S.3
Yang, I.C.-H.4
Reenstra, W.W.5
-
17
-
-
0028928015
-
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein
-
Cell Physiol. 37
-
Illek, B., H. Fischer, G. F. Santos, J. H. Widdicombe, T. E. Machen, and W. W. Reenstra. cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am. J. Physiol. 268 (Cell Physiol. 37): C886-C893, 1995.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Illek, B.1
Fischer, H.2
Santos, G.F.3
Widdicombe, J.H.4
Machen, T.E.5
Reenstra, W.W.6
-
18
-
-
0029665963
-
Activation of endogenous ΔF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition
-
Kelley, T. J., L. Al-Nakkash, C. U. Cotton, and M. L. Drumm. Activation of endogenous ΔF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition. J. Clin. Invest. 98: 513-520, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 513-520
-
-
Kelley, T.J.1
Al-Nakkash, L.2
Cotton, C.U.3
Drumm, M.L.4
-
19
-
-
0029556721
-
CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cells
-
Kelley, T. J., L. Al-Nakkash, and M. L. Drumm. CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cells. Am. J. Respir. Cell. Mol. Biol. 13: 657-664, 1995.
-
(1995)
Am. J. Respir. Cell. Mol. Biol.
, vol.13
, pp. 657-664
-
-
Kelley, T.J.1
Al-Nakkash, L.2
Drumm, M.L.3
-
20
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
Kerem, B.-S., J. M. Rommens, J. A. Buchanan, D. Markiewicz, T. K. Cox, A. Chakravarti, M. Buchwald, and L.-C. Tsui. Identification of the cystic fibrosis gene: genetic analysis. Science 245: 1073-1085, 1989.
-
(1989)
Science
, vol.245
, pp. 1073-1085
-
-
Kerem, B.-S.1
Rommens, J.M.2
Buchanan, J.A.3
Markiewicz, D.4
Cox, T.K.5
Chakravarti, A.6
Buchwald, M.7
Tsui, L.-C.8
-
21
-
-
0028821773
-
Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland
-
Renal Fluid Electrolyte Physiol. 38
-
Lehrich, R. W., and J. N. Forrest, Jr. Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F594-F600, 1995.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
Lehrich, R.W.1
Forrest Jr., J.N.2
-
22
-
-
0026681083
-
Phosphorylation of the cystic fibrosis transmembrane conductance regulator
-
Picciotto, M. R., J. A. Cohn, G. Bertuzzi, P. Greengard, and A, C. Nairn. Phosphorylation of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 267: 12742-12752, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12742-12752
-
-
Picciotto, M.R.1
Cohn, J.A.2
Bertuzzi, G.3
Greengard, P.4
Nairn, A.C.5
-
23
-
-
0029759111
-
CFTR chloride channel activation by genistein: The role of serine/threonine protein phosphatases
-
Cell Physiol. 40
-
Reenstra, W. W., K. Yurko-Mauro, A. Dam, S. Raman, and S. Shorten. CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases. Am. J. Physiol. 271 (Cell Physiol. 40): C650-C657, 1996.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Reenstra, W.W.1
Yurko-Mauro, K.2
Dam, A.3
Raman, S.4
Shorten, S.5
-
24
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan, J. R., J. M. Rommens, B.-S. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.-L. Chou, M. L. Drumm, M. C. Iannuzzi, F. S. Collins, and L.-C. Tsui. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245: 1066-1073, 1989.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.-S.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.-L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.-C.14
-
25
-
-
0028980536
-
CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP
-
Schweibert, E. M., M. E. Eagan, T. H. Hwang, S. B. Fulmer, S. S. Allen, G. R. Cutting, and W. B. Guggino. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 81: 1063-1073, 1995.
-
(1995)
Cell
, vol.81
, pp. 1063-1073
-
-
Schweibert, E.M.1
Eagan, M.E.2
Hwang, T.H.3
Fulmer, S.B.4
Allen, S.S.5
Cutting, G.R.6
Guggino, W.B.7
-
26
-
-
0029202027
-
- secretion in T84 monolayers
-
Gastrointest. Liver Physiol. 32
-
- secretion in T84 monolayers. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G874-G882, 1995.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
Sears, C.L.1
Firoozmand, F.2
Mellander, A.3
Chambers, F.G.4
Eromar, I.G.5
Bot, A.G.M.6
Scholte, B.7
De Jonge, H.R.8
Donowitz, M.9
-
27
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85, 1985.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
28
-
-
0025110836
-
A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells
-
Cell Physiol. 28
-
Venglarik, C. J., R. J. Bridges, and R. A. Frizzell. A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells. Am. J. Physiol. 259 (Cell Physiol. 28): C358-C364, 1990.
-
(1990)
Am. J. Physiol.
, vol.259
-
-
Venglarik, C.J.1
Bridges, R.J.2
Frizzell, R.A.3
-
29
-
-
0031881489
-
Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating: Evidence for two binding sites with opposite effects
-
Wang, F., S. Zeltwanger, I. C.-H. Yang, A. C. Nairn, and T.-C. Hwang. Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating: evidence for two binding sites with opposite effects. J. Gen. Physiol. 111: 477-490, 1998.
-
(1998)
J. Gen. Physiol.
, vol.111
, pp. 477-490
-
-
Wang, F.1
Zeltwanger, S.2
Yang, I.C.-H.3
Nairn, A.C.4
Hwang, T.-C.5
-
30
-
-
0030818110
-
Direct action of genistein on CFTR
-
Weinreich, F., P. G. Wood, J. R. Riordan, and G. Nagel. Direct action of genistein on CFTR. Pflügers Arch. 434: 484-491, 1997.
-
(1997)
Pflügers Arch.
, vol.434
, pp. 484-491
-
-
Weinreich, F.1
Wood, P.G.2
Riordan, J.R.3
Nagel, G.4
-
31
-
-
0027162649
-
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
-
Welsh, M. J., and A. E. Smith. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73: 1251-1254, 1993.
-
(1993)
Cell
, vol.73
, pp. 1251-1254
-
-
Welsh, M.J.1
Smith, A.E.2
-
32
-
-
0003720078
-
-
New York: McGraw-Hill
-
Welsh, M. J., L.-C. Tsui, T. F. Boat, and A. L. Beaudet. The Metabolic and Molecular Basis of Inherited Disease (7th ed.). New York: McGraw-Hill, 1995, p. 3799-3863.
-
(1995)
The Metabolic and Molecular Basis of Inherited Disease (7th Ed.)
, pp. 3799-3863
-
-
Welsh, M.J.1
Tsui, L.-C.2
Boat, T.F.3
Beaudet, A.L.4
-
33
-
-
0021077241
-
Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase
-
Yamamoto, T., S. Yamamoto, J. C. Osborne, V. C. Manganiello, M. Vaughan, and H. Hikada. Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. J. Biol. Chem. 258: 14173-14177, 1983.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 14173-14177
-
-
Yamamoto, T.1
Yamamoto, S.2
Osborne, J.C.3
Manganiello, V.C.4
Vaughan, M.5
Hikada, H.6
-
34
-
-
0031028588
-
Modulation of CFTR chloride channels by calyculin a and genistein
-
Cell Physiol. 41
-
Yang, I. C.-H., T.-H. Cheng, F. Wang, E. M. Price, and T.-C. Hwang. Modulation of CFTR chloride channels by calyculin A and genistein. Am. J. Physiol. 272 (Cell Physiol. 41): C142-C155, 1997.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Yang, I.C.-H.1
Cheng, T.-H.2
Wang, F.3
Price, E.M.4
Hwang, T.-C.5
-
35
-
-
0032161340
-
2aα stimulates CFTR activity by PKA- and PKC-dependent phosphorylation
-
Cell Physiol. 44
-
2aα stimulates CFTR activity by PKA- and PKC-dependent phosphorylation. Am. J. Physiol 275 (Cell Physiol. 44): C653-C660, 1998.
-
(1998)
Am. J. Physiol
, vol.275
-
-
Yurko-Mauro, K.A.1
Reenstra, W.W.2
|