Synthesis of the interferon-α inducer imiquimod by thermal electrocyclic reactions of 1- and 2-azahexatriene systems

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 4, 1996, Pages 709-714

  Yoshioka, Haruyuki ^a   Matsuya, Yuhji ^a   Choshi, Tominari ^a   Sugino, Eiichi ^a   Hibino, Satoshi ^a  

^a FUKUYAMA UNIVERSITY   (Japan)

Author keywords

azahexatriene system; imidazo 4,5 c quinoline; imiquimod thermal electrocyclic reaction; synthesis

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; IMIDAZOQUINOLINE DERIVATIVE; IMIQUIMOD;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

EID: 0029939132     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.709     Document Type: Article

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