Imaging of selective nuclear receptor modulator-induced conformational changes in the nuclear receptor to allow interaction with coactivator and corepressor proteins in living cells

ChemBioChem

Volumn 8, Issue 7, 2007, Pages 737-743

  Awais, Muhammad ^b   Sato, Moritoshi ^a,c   Umezawa, Yoshio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b INSTITUTE FOR MOLECULAR SCIENCE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Coactivators; Conformation change; Corepressors; FRET; Receptors; Selective nuclear receptor modulators

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; CYAN FLUORESCENT PROTEIN; CYPROTERONE ACETATE; DEXAMETHASONE; DIETHYLSTILBESTROL; ESTRADIOL; GENISTEIN; HYBRID PROTEIN; HYDROCORTISONE; MIFEPRISTONE; NONYLPHENOL; PROGESTERONE; PROGESTERONE RECEPTOR; TESTOSTERONE; YELLOW FLUORESCENT PROTEIN; CELL RECEPTOR; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG PROTEIN BINDING; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HORMONE ACTION; IMAGE ANALYSIS; IMMUNOBLOTTING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; HAMSTER; METABOLISM; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CRICETINAE; FLUORESCENCE RESONANCE ENERGY TRANSFER; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS;

EID: 34250860872     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700001     Document Type: Article

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