Terminating the stress: Peripheral peptidolysis of proopiomelanocortin- derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme

Endocrinology

Volumn 148, Issue 6, 2007, Pages 2793-2805

  Scholzen, Thomas E ^a   König, Simone ^a   Fastrich, Michaela ^a   Böhm, Markus ^a   Luger, Thomas A ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; ALPHA INTERMEDIN DERIVATIVE; CORTICOTROPIN; CORTICOTROPIN[1-39]; DIPEPTIDYL CARBOXYPEPTIDASE; MELANOCORTIN RECEPTOR; MEMBRANE METALLOENDOPEPTIDASE; METALLOPROTEINASE INHIBITOR; PEPTIDASE; PROOPIOMELANOCORTIN; TETRACOSACTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MEMBRANE; CELL SPECIFICITY; CONTROLLED STUDY; DISEASE MODEL; ELECTROSPRAY MASS SPECTROMETRY; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME DEGRADATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROVASCULARIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN ALLERGY; STRESS;

ADRENOCORTICOTROPIC HORMONE; ALPHA-MSH; AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; ENDOTHELIAL CELLS; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NEPRILYSIN; PEPTIDYL-DIPEPTIDASE A; PRO-OPIOMELANOCORTIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SKIN; STRESS;

EID: 34250818924     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1765     Document Type: Article

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