Neutral endopeptidase expression and distribution in human skin and wounds

Journal of Investigative Dermatology

Volumn 112, Issue 6, 1999, Pages 873-881

  Olerud, John E ^c,d   Usui, Marcia L ^c   Seckin, Deniz ^c   Chiu, Diane S ^c   Haycox, Claire L ^c   Song, In Sung ^a   Ansel, John C ^a   Bunnett, Nigel W ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

Endothelial cells; Epidermis; Fibroblasts; Hair follicles; Keratinocytes; Nerves; Neutral endopeptidase; Wound healing

Indexed keywords

MEMBRANE METALLOENDOPEPTIDASE; NEUROPEPTIDE; SUBSTANCE P;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EPIDERMIS; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SENSORY NERVE; SKIN INFLAMMATION; WOUND HEALING;

EID: 0742299373     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1999.00596.x     Document Type: Article

References (54)

1. Alonso S, Minty A, Bourlet Y, Buckingham M: Comparison of three actin-coding sequences in the mouse: evolutionary relationship between the actin genes of warm-blooded vertebrates. J Mol Evol 23:11-22, 1986
2. Ansel JC, Kaynard AH, Armstrong CA, Olerud J, Bunnett N, Payan D: Skin-nervous system interactions. J Invest Dermatol 106:198-204, 1996
3. Appelboom T, de Maertelaer V, de Prez E, Hauzeur JP, Deschodt-Lanckman M: Enkephalinase: a physiologic neuroimmunomodulator detected in the synovial fluid. Arthritis Rheum 34:1048-1051, 1991
4. Bohm SK, Grady EF, Bunnett NW: Regulatory mechanisms that modulate signaling by G-protein coupled receptors. Biochem J 322:1-18, 1997
5. Borson DB: Roles of neutral endopeptidase in airways. Am J Physiol 260:212-225, 1991
6. Bou-Gharios G, Osman J, Atherton A, Monoghan P, Vancheeswaran R, Black C, Olsen I: Expression of ectopeptidases in scleroderma. Ann Rheum Dis 54:111-116, 1995
7. Braun MP, Martin PJ, Ledbetter JA, Hansen JA: Granulocytes and cultured human fibroblasts express common acute lymphoblastic leukemia-associated antigens. Blood 61:718-725, 1984
8. Bunnett NW, Wu V, Sternini C, et al: Distribution and abundance of neutral endopeptidase (EC 3.4.24.11) in the alimentary tract of the rat. Am Physiol Soc 0193-1875/93:G497-G508, 1993
9. Carvalho KM, Joudiou C, Boussetta H, Leseney A-M, Cohen P: A peptide-hormone inactivating endopeptidase in Xenopus iaevis skin secretion. Proc Natl Acad Sci USA 89:84-88, 1992
10. Cooper D, Sun TT: Monoclonal antibody analysis of bovine epithelial keratins. Specific pairs as defined by coexpression. J Biol Chem 261:4646-4654, 1986
11. Dale BA, Holbrook KA, Fleckman P, Kimball JR, Brumbaugh S, Sybert VP: Heterogeneity in harlequin ichthyosis, an inborn error of epidermal keratinization: variable morphology and structural protein expression and a defect in lamellar granules. J Invest Dermatal 94:6-18, 1990
12. Feinberg AP, Vogelstein B: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-10, 1983
13. Feinberg AP, Vogelstein B: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Addendum. Anal Biochem 137:266-267, 1984
14. Fleckman P, Hager B, Dale BA: Harlequin ichthyosis keratinocytes in lifted culture differentiate poorly by morphologic and biochemical criteria. J Invest Dermatol 109:36-38, 1997
15. Foreman J, Jordan C: Neurogenic inflammation. Trends Pharmacol Sci 5:116-119, 1984
16. Headington JC: Transverse microscopic anatomy of the human scalp. A basis for a morphometric approach to disorders of the hair follicle. Arch Derm 120:449-456, 1984
17. Hilliges M, Wang L, Johansson O: Ultrastructural evidence for nerve fibers within all vital layers of the human epidermis. J Invest Dermatol 104:134-137, 1995
18. Holzer P: Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinin, calcitonin gene-related peptide and other neuropeptides, Neuroscience 24:739-768, 1988
19. Hosoi J, Murphy GF, Egan CL, Lemer EA, Grabbe S, Asahina A, Granstein RD: Regulation of Langerhans cell function by nerves containing calcitonin gene-related peptide. Nature 363:159-163, 1993
20. Iwamoto I, Ueki IF, Borson DB, Nadel JA: Neutral endopeptidase modulates tachykinin-induced increase in vascular permeability in guinea pig skin. Int Arch Allergy Appl Immunol 88:288-293, 1989
21. Johnson AR, Ashton J, Schulz WW, Erdös EG: Neutral metalloendopeptidase in human lung tissue and cultured cells. Am Rev Respir Dis 132:564-568, 1985
22. Katayama M, Nadel JA, Bunnett NW, DiMaria GU, Haxhiu M, Borson DB: Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase. Peptides 12:563-567, 1991
23. Kummer W, Fischer A: Tissue distribution of neutral endopeptidase 24.11 ("enkephalinase") activity in guinea pig trachea. Neuropeptides 18:181-186, 1991
24. Kummer W, Fischer A, Preissler U, Couraud JY, Heym C: Immunohistochemistry of the guinea-pig trachea using an anti-idiotypic antibody recognizing substance P receptors. Histochemistry 93:541-546, 1990
25. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685, 1970
26. Lembeck F, Holzer P: Substance P as neurogenic mediator of antidromic vasodilatation and neurogenic plasma extravasation. Naunyn-Schmeideberg's Arch Pharmacol 310:175-183, 1979
27. Levy DM, Terenghi G, Gu X-H, Abraham RR, Springall DR, Polak JM: Immunohistochemical measurements of nerves and neuropeptides in diabetic skin: relationship to test of neurological function. Diabetologia 35:889-897, 1992
28. Lorkowski G, Zijderhand-Bleekemolen JE, Von Erdös EG, Figura K, Hasilik A: Neutral endopeptidase-24.11 (enkephalinase). Biochem J 248:345-350, 1987
29. Lu B, Figini M, Emanueli C, et al: The control of microvascular permeability and blood pressure by neutral endopeptidase. Nature Med 3:904-907, 1997
30. Malfroy B, Kuang W-J, Seeburg PH, Mason AJ, Schofield PR: Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase). FEBS Lett 229:1206-1210, 1988
31. Matis WL, Lavker RM, Murphy GF: Substance P induces the expression of an endothelial leukocyte adhesion molecule by microvascular endothelium. J Invest Dermatol 94:492-495, 1990
32. Matsas R, Kenny J, Turner AJ: The metabolism of neuropeptides. Biochem J 223:433-440, 1984
33. Nadel JA: Neutral endopeptidase modulation of neurogenic inflammation in airways. Eur Respir J 3 (Suppl. 12):645S-651S, 1990
34. Nadel JA, Borson DB: Modulation of neurogenic inflammation by neutral endopeptidase. Am. Rev Respir Dis 143:S33-S36, 1991
35. Nilsson J, von Euler AM, Dalsgaard C-J: Stimulation of connective tissue cell growth by substance P and substance K. Nature 315:61-63, 1985
36. Ohkubo K, Okuda M, Kaliner M: Immunological localization of neuropeptide-degrading enzymes in the nasal mucosa. Rhinology 31:130-133, 1994
37. Öhlén A, Thureson-Klein Å, Lindbom L, Persson M, Hedqvist P: Substance P activates leukocytes and platelets in rabbit microvessels. Blood Vessels 26:84-94, 1989
38. 1) receptor expressed in mammalian cells. Biochem J 299:683-693, 1994
39. Olerud JE, Odland GF, Burgess EM, Wyss CR, Fisher LD, Matsen FA 3rd: A model for the study of wounds in normal elderly adults and patients with peripheral vascular disease or diabetes mellitus. J Surg Res 59:349-360, 1995
40. Otsuka M, Yoshioka K: Neurotransmitter functions of mammalian tachykinins, Physiol Rev 73:229-281, 1993
41. Paus R, Heinzelmann T, Schultz KD, Furkert J, Fechner K, Czametzki BM: Hair growth induction by substance P. Lab Invest 1:134-140, 1994
42. Plowman GD, Culouscou JM, Whitney GS, et al: Ligand-specific activation of HER 4/pl 80erbB4, a fourth member of the epidermal growth factor receptor family. Proc Natl Acad Sci USA 90:1746-1750, 1993
43. Quinlan KL, Song IS, Bunnett NW, et al: Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-I expression and function. Am J Physiol 275 (Cell Physiol 44): C1580-C1590, 1998
44. Roques BP, Nobel F, Dauge V, Fournié-Zaluski M-C, Beaumont A: Neutral endopeptidase 24.11: Structure, inhibition, and experimental and clinical pharmacology. Pharmacol Rev 45:87-133, 1993
45. Rubenstein I, Iwamoto I, Ueki I, Borson DB, Nadel JA: Recombinant neutral endopeptidase attenuates substance P-induced plasma extravasation in the guinea pig skin. Int Arch Allergy Appl Immunol 91:232-238, 1990
46. Ruff MR, Wahl SM, Pert CB: Substance P receptor-mediated chemotaxis of human monocytes. Peptides 6 (Suppl. 2):107-111, 1985
47. Sambrook J, Fritsch EF, Mariatis T. Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989
48. Spillantini MG, Siduteri F, Salmon S, Malfroy B: Characterization of endopeptidase 3.4.23.11 ('Enkephalase') activity in human plasma and cerebrospinal fluid. Biochem Pharmacol 39:1353-1356, 1990
49. Swerlick RA, Garcia-Gonzalez E, Kubota Y, Xu YL, Lawley TJ: Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal microvascular endothelial cells. J Invest Dermatol 97:190-196, 1991
50. Tanaka T, Danno K, Ikai K, Imamura S: Effects of substance P and substance K on the growth of cultured keratinocytes. J Invest Dermatol 90:399-401, 1988
51. Terashima H, Okamoto A, Menozzi D, Goetzl EJ, Bunnett NW: Identification of neuropeptide-degrading enzymes in the pancreas. Peptides 13:741-748, 1992
52. Towbin H, Staehalin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354, 1979
53. Waksman G, Hamel E, Fournié-Zaluski MC, Roques BP: Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid in rat brain. Proc Natl Acad Sci USA 83:1523-1527, 1986
54. Ziche M, Morbidelli L, Pacini M, Geppetti P, Alessandri G, Maggi CA: Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. Microvascular Res 40:264-278, 1990