Suppressive effect of a novel water-soluble artemisinin derivative SM905 on T cell activation and proliferation in vitro and in vivo

European Journal of Pharmacology

Volumn 564, Issue 1-3, 2007, Pages 211-218

  Wang, Jun Xia ^a   Tang, Wei ^a   Yang, Zhong Shun ^a   Wan, Jin ^a   Shi, Li Ping ^a   Zhang, Yu ^a   Zhou, Ru ^a   Ni, Jia ^a   Hou, Li Fei ^a   Zhou, Yu ^a   He, Pei Lan ^a   Yang, Yi Fu ^a   Li, Ying ^a   Zuo, Jian Ping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Artemisinin derivative; Immunosuppression; MAP kinase; Ras; SM905; T cell activation and proliferation

Indexed keywords

1 (12BETA DIHYDROARTEMISINOXY) 2 HYDROXY 3 TERT BUTYLAMINOPROPANE MALEATE; ARTEMISIN DERIVATIVE; CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OVALBUMIN; RAS PROTEIN; SM 905; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; FEMALE; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD28; ARTEMISININS; CELL PROLIFERATION; CONCANAVALIN A; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; INTERLEUKIN-2; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVALBUMIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RAS PROTEINS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SPLEEN; T-LYMPHOCYTES;

EID: 34250752352     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.01.092     Document Type: Article

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