The role of DNA strand breaks in human spermatozoa used for IVF and ICSI

Acta Obstetricia et Gynecologica Scandinavica

Volumn 79, Issue 7, 2000, Pages 559-563

  Høst, Erik ^a   Lindenberg, Svend ^a   Smidt Jensen, Steen ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Apoptosis; DNA strand breaks; Fertilization rate; ICSI; IVF

Indexed keywords

ARTICLE; DNA STRAND BREAKAGE; EMBRYO; EMBRYO CULTURE; EMBRYO TRANSFER; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; OLIGOSPERMIA; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERMATOZOON; UTERINE TUBE OCCLUSION;

ADULT; APOPTOSIS; DNA DAMAGE; FALLOPIAN TUBE DISEASES; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; HUMANS; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; OLIGOSPERMIA; PREGNANCY; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA;

EID: 0033947956     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0412.2000.079007559.x     Document Type: Article

References (14)

1. 1. Krüger TF, Menkveld R, Stander FSH, Lombard CJ, Van der Merve JP, Van Zyl JA et al. Sperm morphologic features as a prognostic factor in in vitro fertilization. Fertil Steril 1986; 46: 1118-23.
2. 2. Krüger TF, Acosin AA, Simmons KF, Swanson RJ, Matta JF, Oehninger S. Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 1988; 49: 112-17.
3. 3. Krüger TF, Coetzee K. The role of sperm morphology in assisted reproduction. Hum Reprod Update 1999; 5: No. 2: 172-8.
4. 4. World Health Organization (1992) WHO Laboratory Manual of the examination of Human Semen and Sperm - Cervical Mucus Interaction, 3rd edn. Cambridge University Press, 1992.
5. 5. Billig H, Chun SY, Eisenhauer K, Hsueh AJ. Gonadal cell apoptosis: hormone-regulated cell demise. Hum Reprod Update 1996; 2: 103-17.
6. 6. Henriksén K, Toppari J, Heiskanen P, Dunkel L, Parvinen M. Apoptosis in the testis. J Frontiers in Endocrinology 1995; 18: 35-41.
7. 7. Vinatier D, Dufour Ph, Subtil D. Apoptosis: A programmed cell death involved in ovarian and uterine physiology. Eur J Obstet Gynecol Reprod Biol 1996; 67: 85-102.
8. 8. De Lamirande E, Gagnon C. Impact of reactive oxygen species on spermatozoa: A balancing act between beneficial and detrimental effect. Hum Reprod 1995; Oct. 10 (Suppl 1): 15-21.
9. 9. Higuchi M, Singh S, Chan H, Aggarwal BB. Protease inhibitors differentially regulate tumor necrosis factor-induced apoptosis, nuclear factor-kappa B activation, cytotoxicity and differentiation. Blood 1995; 86: 2248-56.
10. 10. Sun JG, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 1997; 56: 602-7.
11. 11. Gabrielsen A, Petersen K, Mikkelsen AL, Lindenberg S. Intracytoplasmic sperm injection does not overcome an oocyte defect in previous fertilization failure with conventional in-vitro fertilization and normal spermatozoa. Hum Reprod 1996; 11: 1963-5.
12. 12. Høst E, Lindenberg S, Kahn JA, Christensen F. DNA strand breaks in human sperm cells: A comparison between men with normal and oligozoospermic sperm samples. Acta Obstet Gynecol Scand 1999; 78: 336-9.
13. 13. Van den Abbeel E, Van der Elst J, Van Waesberghe I, Camus M, Devroey P, Khan I et al. Hyperstimulation: the need for cryopreservation of embryos. Hum Reprod 1988; 3: 53-7.
14. 14. Høst E, Lindenberg S, Ernst E, Christensen F. DNA strand breaks in human spermatozoa: a possible factor, to be considered in couples suffering from unexplained infertility. Acta Obstet Gynecol Scand 1999; 78: 622-5.