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Volumn 4, Issue 1, 1998, Pages 103-105

The comet assay: A new method to examine heterogeneity associated with solid tumors

Author keywords

[No Author keywords available]

Indexed keywords

TIRAPAZAMINE;

EID: 0031939561     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0198-103     Document Type: Review
Times cited : (70)

References (18)
  • 1
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation-inducec DMA damages in individual mammalian cells
    • Ostling, O. & Johanson, K.J. Microelectrophoretic study of radiation-inducec DMA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123, 291-298 (1984).
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 291-298
    • Ostling, O.1    Johanson, K.J.2
  • 3
    • 0027319158 scopus 로고
    • The single cell get electrophoresis assay (COMET assay): A European review
    • McKelvey-Martin, V.M., et al. The single cell get electrophoresis assay (COMET assay): A European review. Mutat. Res. 288, 47-63 (1993).
    • (1993) Mutat. Res. , vol.288 , pp. 47-63
    • McKelvey-Martin, V.M.1
  • 4
    • 0028092855 scopus 로고
    • Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage
    • Singh, N.P., Stephens, R.E. & Schneider, E.L. Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage. Int. J. Radiat. Biol. 66, 23-28 (1994).
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 23-28
    • Singh, N.P.1    Stephens, R.E.2    Schneider, E.L.3
  • 5
    • 0024360794 scopus 로고
    • Therapeutic implications of tumor heterogeneity
    • Heppner, G.H. & Miller, B.E. Therapeutic implications of tumor heterogeneity. Seminars Oncology 16, 91-105 (1989).
    • (1989) Seminars Oncology , vol.16 , pp. 91-105
    • Heppner, G.H.1    Miller, B.E.2
  • 6
    • 0026659839 scopus 로고
    • Detecting hypoxic cells in a murine tumor using the comet assay
    • Olive, P.L & Durand, R.E. Detecting hypoxic cells in a murine tumor using the comet assay. J. Natl. Cancer Inst. 85, 707-711 (1992).
    • (1992) J. Natl. Cancer Inst. , vol.85 , pp. 707-711
    • Olive, P.L.1    Durand, R.E.2
  • 7
    • 0027534567 scopus 로고
    • Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers
    • Olive, P.L., Durand, R.E., Le Riche, J., Olivotto, I. & Jackson, S.M. Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers. Cancer Res. 53, 733-736 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 733-736
    • Olive, P.L.1    Durand, R.E.2    Le Riche, J.3    Olivotto, I.4    Jackson, S.M.5
  • 8
    • 0029740039 scopus 로고    scopus 로고
    • Use of the comet assay to identify cells sensitive to tirapazamine in multicell spheroids and tumors in mice
    • Olive, P.L., Vikse, C.M. & Banáth, J.P. Use of the comet assay to identify cells sensitive to tirapazamine in multicell spheroids and tumors in mice. Cancer Res. 56, 4460-4463 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 4460-4463
    • Olive, P.L.1    Vikse, C.M.2    Banáth, J.P.3
  • 9
    • 0031454075 scopus 로고    scopus 로고
    • Multicell spheroid response to drugs predicted with the comet assay
    • Olive, P.L. & Banáth, J.P. Multicell spheroid response to drugs predicted with the comet assay. Cancer Res. 57, 5528-5533 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 5528-5533
    • Olive, P.L.1    Banáth, J.P.2
  • 10
    • 0028884765 scopus 로고
    • Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent
    • Olive, P.L. & Banáth, J.P. Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp. Celt Res. 221, 19-26 (1995).
    • (1995) Exp. Celt Res. , vol.221 , pp. 19-26
    • Olive, P.L.1    Banáth, J.P.2
  • 11
    • 0026786492 scopus 로고
    • Tumor growth fraction measured using the comet assay
    • Olive, P.L. & Banáth, J.P. Tumor growth fraction measured using the comet assay. Cell Prolif. 25, 447-457 (1992).
    • (1992) Cell Prolif. , vol.25 , pp. 447-457
    • Olive, P.L.1    Banáth, J.P.2
  • 12
    • 1842290989 scopus 로고    scopus 로고
    • DNA excision repair profiles of normal and leukemic human lymphocytes: Functional analysis at the single-cell level
    • Buschfort, C., Muller, M.R., Seeber, S., Rajewsky, M.F, & Thomale, J. DNA excision repair profiles of normal and leukemic human lymphocytes: Functional analysis at the single-cell level. Cancer Res. 57, 651-658 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 651-658
    • Buschfort, C.1    Muller, M.R.2    Seeber, S.3    Rajewsky, M.F.4    Thomale, J.5
  • 13
    • 0028123570 scopus 로고
    • Measuring DNA damage in individual cells of heterogenous mixtures: A novel application of an immunological typing technique
    • Strauss, G.H.S., Peters, W.P. & Everson, R.B. Measuring DNA damage in individual cells of heterogenous mixtures: A novel application of an immunological typing technique. Mutat. Res. 304, 211-216 (1994).
    • (1994) Mutat. Res. , vol.304 , pp. 211-216
    • Strauss, G.H.S.1    Peters, W.P.2    Everson, R.B.3
  • 14
    • 0031148618 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization with comets
    • Santos, S.J., Singh, N.P. & Natarajan, A.T. Fluorescence in situ hybridization with comets. Exp. Cell Res. 232, 407-411 (1997).
    • (1997) Exp. Cell Res. , vol.232 , pp. 407-411
    • Santos, S.J.1    Singh, N.P.2    Natarajan, A.T.3
  • 15
    • 0022258449 scopus 로고
    • Cell selection from a murine tumor using the fluorescent probe Hoechst 33342
    • Chaplin, D.J., Durand, R.E. & Olive, P.L. Cell selection from a murine tumor using the fluorescent probe Hoechst 33342. Br. J. Cancer 51, 569-572 (1985).
    • (1985) Br. J. Cancer , vol.51 , pp. 569-572
    • Chaplin, D.J.1    Durand, R.E.2    Olive, P.L.3
  • 16
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay
    • Olive, P.L., Banáth, J.P. & Durand, R.E. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat. Res. 122, 69-72 (1990).
    • (1990) Radiat. Res. , vol.122 , pp. 69-72
    • Olive, P.L.1    Banáth, J.P.2    Durand, R.E.3
  • 18
    • 0027375157 scopus 로고
    • Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA
    • Collins, A.R., Duthie, S.J. & Dobson, V.L. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 14, 1733-1735 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 1733-1735
    • Collins, A.R.1    Duthie, S.J.2    Dobson, V.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.