Predicting human skin absorption of chemicals: Development of a novel quantitative structure activity relationship

Toxicology and Industrial Health

Volumn 23, Issue 1, 2007, Pages 39-45

  Luo, Wen ^a   Medrek, Sarah ^b   Misra, Jatin ^c   Nohynek, Gerhard J ^a  

^a L ORÉAL RECHERCHE   (France)

^b Princeton University   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

lipophilicity; molecular weight; QSAR; quantitative structure activity relationship; skin absorption; skin permeability; statistical validation

Indexed keywords

CHEMICAL AGENT;

ARTICLE; COMPUTER PROGRAM; DATA BASE; EXTERNAL VALIDITY; INTERNAL VALIDITY; MOLECULAR SIZE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; RISK ASSESSMENT; SCREENING; SKIN ABSORPTION;

DATABASES, FACTUAL; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PERMEABILITY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REPRODUCIBILITY OF RESULTS; SKIN ABSORPTION;

EID: 34250714908     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233707077430     Document Type: Article

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