Prediction of percutaneons absorption from physicochemical data: A model based on data of in vitro experiments

Annals of Occupational Hygiene

Volumn 42, Issue 4, 1998, Pages 267-276

  Sartorelli, Pietro ^a   Aprea, Cristina ^a   Cenni, Anna ^a   Novelli, Maria Teresa ^a   Orsi, Daniela ^a   Palmi, Silvana ^b   Matteucci, Giacomo ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b ISPESL   (Italy)

^c Biocine Sclavo   (Italy)

Author keywords

Percutaneous absorption; Physicochemical data; Predictive model

Indexed keywords

ACENAPHTHENE DERIVATIVE; ACEPHATE; ACETONE; ANTHRACENE; BENZ[A]ANTHRACENE; BOVINE SERUM ALBUMIN; CHLORPYRIFOS; CHRYSENE; DIMETHOATE; FENITROTHION; FLUORENE; GENTAMICIN; HERBICIDE; INDUSTRIAL CHEMICAL; METHAMIDOPHOS; NAPHTHALENE; OCTANOL; ORGANOPHOSPHATE INSECTICIDE; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; SODIUM CHLORIDE; WATER;

ALGORITHM; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DIFFUSION CHAMBER; IN VITRO STUDY; MATHEMATICAL MODEL; MOLECULAR WEIGHT; MONKEY; MULTIPLE REGRESSION; NONHUMAN; PARTITION COEFFICIENT; PERMEABILITY; PHYSICAL CHEMISTRY; PREDICTION; PRESSURE; PRIORITY JOURNAL; SKIN ABSORPTION; SOLUBILITY; STATISTICAL ANALYSIS; TIME; VAPOR; ANIMAL; CERCOPITHECUS; DANGEROUS GOODS; METABOLISM; OCCUPATIONAL HEALTH; STATISTICAL MODEL; THEORETICAL MODEL;

ABSORPTION; AROMATIC HYDROCARBONS; DIFFUSION IN SOLIDS; HERBICIDES; INSECTICIDES; MATHEMATICAL MODELS; MECHANICAL PERMEABILITY; MOLECULAR WEIGHT; REGRESSION ANALYSIS; SOLUBILITY; VAPOR PRESSURE;

PERCUTANEOUS ABSORPTION;

OCCUPATIONAL RISKS;

ANIMALS; CERCOPITHECUS; HAZARDOUS SUBSTANCES; LINEAR MODELS; MODELS, THEORETICAL; OCCUPATIONAL HEALTH; SKIN ABSORPTION;

EID: 0031594861     PISSN: 00034878     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4878(98)00021-0     Document Type: Article

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