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Volumn 22, Issue 3, 1999, Pages 281-287
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Theoretical analysis of the effect of cutaneous metabolism on skin permeation of parabens based on a two-layer skin diffusion/metabolism model
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Author keywords
Cutaneous metabolism; Diffusion metabolism model; Drug lipophilicity; Enzyme inhibitor; Percutaneous penetration; Skin
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Indexed keywords
4 HYDROXYBENZOIC ACID;
BUTYL PARABEN;
DYFLOS;
ESTERASE INHIBITOR;
PROPYL PARABEN;
ANIMAL TISSUE;
ARTICLE;
CONTROLLED STUDY;
DIFFUSION;
DRUG METABOLISM;
DRUG PENETRATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
IN VITRO STUDY;
LIPOPHILICITY;
MALE;
MATHEMATICAL MODEL;
METABOLIC RATE;
NONHUMAN;
PARTITION COEFFICIENT;
RAT;
SIMULATION;
SKIN ABSORPTION;
SKIN PENETRATION;
STRATUM CORNEUM;
TRANSDERMAL DRUG ADMINISTRATION;
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EID: 0032907905
PISSN: 09186158
EISSN: None
Source Type: Journal
DOI: 10.1248/bpb.22.281 Document Type: Article |
Times cited : (27)
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References (10)
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