Inhibition of VMAT-2 and DT-diaphorase induce cell death in a substantia nigra-derived cell line - An experimental cell model for dopamine toxicity studies

Chemical Research in Toxicology

Volumn 20, Issue 5, 2007, Pages 776-783

  Fuentes, Patricio ^a   Paris, Irmgard ^a   Nassif, Melissa ^a   Caviedes, Pablo ^a   Segura Aguilar, Juan ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

DICOUMAROL; DOPAMINE; MELANIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); RESERPINE; VESICULAR MONOAMINE TRANSPORTER 2;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL LINE; CHROMATIN CONDENSATION; DRUG EFFECT; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELL DEATH; CELLS, CULTURED; DICUMAROL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; MITOCHONDRIA; NAD(P)H DEHYDROGENASE (QUINONE); NEURONS; RATS; RATS, INBRED F344; RESERPINE; SUBSTANTIA NIGRA; VESICULAR MONOAMINE TRANSPORT PROTEINS;

RATTUS;

EID: 34250702138     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx600325u     Document Type: Article

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