Effect of cryoprotectant and freeze-drying process on the stability of W/ O/W emulsions

Drying Technology

Volumn 25, Issue 5, 2007, Pages 809-819

  Choi, M J ^a   Briancon S ^a   Bazile, D ^b   Royere, A ^b   Min, S G ^c   Fessi, H ^a  

^a UNIVERSITÉ LYON 1   (France)

^b MainLab   (France)

^c Konkuk University   (South Korea)

Author keywords

Cryoprotectant; Freeze drying; Freezing rate; Stability; Sublimation temperature; W O W emulsions

Indexed keywords

DRUG DELIVERY; DRYING; FREEZING; GLASS TRANSITION; PARTICLE SIZE ANALYSIS; SUBLIMATION; TEMPERATURE; ULTRAVIOLET SPECTROPHOTOMETERS;

CRYOPROTECTANT; FREEZE-DRYING TECHNOLOGY; FREEZING RATRE; SUBLIMATION TEMPERATURE;

EMULSIONS;

DRUG DELIVERY; DRYING; EMULSIONS; FREEZING; GLASS TRANSITION; PARTICLE SIZE ANALYSIS; SUBLIMATION; TEMPERATURE; ULTRAVIOLET SPECTROPHOTOMETERS;

EID: 34250686610     PISSN: 07373937     EISSN: 15322300     Source Type: Journal    
DOI: 10.1080/07373930701370183     Document Type: Article

References (36)

1. Mollet, H. and Grubenmann, A. (2001) Formulation Technology; Emulsion, Suspension, Solid Forms, Emulsions-Properties and Production, Wiley-VCH, New York
2. Clausse, D., Gomez, F., Pezron, I., Komunjer, L. and Dalmazzone, C. (2005) Morphology characterization of emulsion by differential scanning calorimetry. Advances in Colloid and Interface Science, 117, pp. 59-74.
3. Clausse, D., Gomez, F., Dalmazzone, C. and Noik, C.A. (2005) Method for the characterization of emulsions, thermogranulometry: Application to water-in-crude oil emulsion. Journal of Colloid and Interface Science, 287, pp. 694-703.
4. Benichou, A., Aserin, A. and Garti, N. (2002) Double emulsions stabilized by new molecular recognition hybrids of natural polymers. Polymers for Advanced Technologies, 13, pp. 1019-1031.
5. Adachi, S., Imaoka, H., Ashida, H., Maeda, H. and Matsuno, R. (2004) Preparation of microcapsules of W/O/W emulsions containing a polysaccharide in the outer aqueous phase by spray-drying. European Journal of Lipid Science Technology, 106, pp. 225-231.
6. Cournarie, F., Rosilio, V., Chéron, M., Vauthier, C., Lacour, C.B., Grossiord, J.L. and Seiller, M. (2004) Improved formulation of W/O/ W multiple emulsion for insulin encapsulation; Influence of the chemical structure of insulin. Colloid Polymer Science, 282, pp. 562-568.
7. Sipos, P., Csóka, I., Srčič, S., Pintye-Hódi, K. and Eros, I. (2005) Influence of preparation conditions on the properties of eudragit microspheres produced by a double emulsion method. Drug Development Research, 64, pp. 41-54.
8. Raynal, S., Grossiord, J.L., Seiller, M. and Clausse, D. (1993) A topical W/O/W multiple emulsion containing several active substances: Formulation, characterization and study of release. Journal of Controlled Release, 26, pp. 129-140.
9. Van der Horst, B.M., Langelaan, H.C. and Gotsis, A.D. (2000) Rheological studies of water-in-oil-in-water double emulsions. Progress Colloid Polymer Science, 115, pp. 315-319.
10. Muguet, V., Seiller, M., Barratt, G., Clausse, D., Marty, J.P. and Grossiord, J.L. (1999) W/O/W multiple emulsions submitted to a linear shear flow: Correlation between fragmentation and release. Journal of Colloid and Interface Science, 218, pp. 335-337.
11. Jager-Lezer, N., Terrisse, I., Bruneau, F., Tokgoz, S., Ferreira, L. and Clausse, D. (1997) Influence of lipophilic surfactant on the release kinetics of water-soluble molecules entrapped in a W/O/W multiple emulsion. Journal of Controlled Release, 45, pp. 1-13.
12. Kovács, A., Csóka, I., Kónya, M., Csányi, E., Fehér, A. and Eros, I. (2006) Structural analysis of W/O/W multiple emulsions by means of DSC. Journal of Thermal Analysis and Calorimetry, 82, pp. 491-497.
13. Pikal, M.J. (1994) Freeze-drying of proteins. ACS Symposium Series, American Chemical Society.pp. 120-133.
14. De Chasteigner, S., Fessi, H., Cavé, G., Devissaguet, J.P. and Puisieux, F. (1995) Gastro-intestinal tolerance study of a freeze-dried oral dosage form of indomethacin-loaded nanocapsules. S.T.P. Pharma Science, 5:3, pp. 242-246.
15. Wang, B., Zhang, W., Zhang, W., Mujumdar, A.S. and Huang, L. (2005) Progress in drying technology for nanomaterials. Drying Technology, 23:1, pp. 7-32.
16. Tamon, H. and Ishizaka, H. (1999) Preparation of organic mesoporous gel by supercritical/freeze drying. Drying Technology, 17, pp. 1653-1665.
17. Tamon, H., Ishizaka, H., Yamamoto, T. and Suzuki, T. (2001) Freeze-drying for preparation of aerogel-like carbon. Drying Technology, 19:2, pp. 313-324.
18. Choi, M.J., Briançon, S., Andrieu, J., Min, S.G. and Fessi, H. (2004) Effect of freeze-drying process conditions on the stability of nanoparticles. Drying Technology, 22, pp. 335-346.
19. Corveleyn, S. and Remon, J.P. (1998) Formulation of a lyophilized dry emulsion tablet for the delivery of poorly soluble drugs. International Journal of Pharmaceutics, 166, pp. 65-74.
20. Bamba, J., Cavé, G., Bensouda, Y., Tchoreloff, P., Puisieux, F. and Couarraze, G. (1995) Cryoprotection of emulsions in freeze-drying: Freezing process analysis. Drug Development and Industrial Pharmacy, 21, pp. 1749-1760.
21. Toorisaka, E., Hashida, M., Kamiya, N., Ono, H., Kokazu, Y. and Goto, M. (2005) An eutectic-coated dry emulsion formulation for oral insulin delivery. Journal of Controlled Release, 107, pp. 91-96.
22. Christensen, K.L., Pedersen, G.P. and Kristensen, H.G. (2002) Physical stability of redispersible dry emulsions containing amorphous sucrose. European Journal of Pharmaceutics and Biopharmaceutics, 53, pp. 147-153.
23. Giese, J. (1993) Packaging, storage, and delivery of ingredients. Food Technology, 47, pp. 54-58.
24. Charlesworth, W.R. and Marchall, J.R. (1960) Evaporation from droplets containing dissolved solids. AIChE Journal, 6, pp. 9-23.
25. Dumas, J.P., Clausse, D. and Broto, F. (1975) A study of thermograms obtained through differential scanning calorimetry of an emulsion of a supercooled liquid. Thermochimica Acta, 13, pp. 261-275.
26. Potier, L., Raynal, S., Seiller, S., Grossiord, J.L. and Clausse, D. (1992) Study of state transitions within multiple W/O/W emulsions using calorimetry (DSC). Thermochimica Acta, 204, pp. 145-155.
27. 4. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 91, pp. 191-205.
28. Clausse, D., Pezron, I. and Komunjer, L. (1999) Stability of W/O and W/O/ W emulsions as a result of partial solidification. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 152, pp. 23-29.
29. Pikal, M.J. (1990) Freeze-drying of proteins, part I: Process design. BioPharm.3:8, pp. 26-28.
30. Roos, Y. (1993) Melting and glass transitions of low molecular weight carbohydrates. Carbohydrate Research, 238, pp. 39-48.
31. Yamamoto, T., Nishimura, T., Suzuki, T. and Tamon, H. (2001) Effect of drying method on mesoporosity of resorcinol-formaldehyde dry gel and carbon gel. Drying Technology, 19:7, pp. 1319-1333.
32. Reid, D.S. (1984) Cryomicroscopic studies of the freezing of model solutions of cryobiological interest. Cryobiology, 21, pp. 60-67.
33. Chen, T., Bhowmick, S., Sputtek, A., Fowler, A. and Toner, M. (2002) The glass transition temperature of mixtures of trehalose and hydroxyethyl starch. Cryobiology, 44, pp. 301-306.
34. Crowe, J.H., Oliver, A.E., Hoekstra, F.A. and Crowe, L.M. (1997) Stabilization of dry membranes by mixtures of hydroxyethyl starch and glucose: The role of vitrification. Cryobiology, 35, pp. 20-30.
35. Kumagai, H., MacNaughtan, W., Farhat, I.A. and Mitchell, J.R. (2002) The influence of carrageenan on molecular mobility in low moisture amorphous sugars. Carbohydrate Polymer, 48, pp. 341-349.
36. Crowe, J.H., Tablin, F., Wolkers, W.F., Gousset, K., Tsvetkova, N.M. and Ricker, J. (2003) Stabilization of membranes in human platelets freeze-dried with trehalose. Chemistry and Physics of Lipids, 122, pp. 41-52.