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Volumn 127, Issue 6, 2007, Pages 954-960

Correlation of serum TNF-α levels and histologic liver injury scores in pediatric nonalcoholic fatty liver disease

Author keywords

Inflammation; Insulin resistance; Leptin; NAFLD; NASH; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Receiver operating characteristic curves; TNF ; Tumor necrosis factor

Indexed keywords

ALKALINE PHOSPHATASE; LEPTIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 34250632770     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/6VJ4DWGYDU0XYJ8Q     Document Type: Article
Times cited : (147)

References (37)
  • 1
    • 0030872385 scopus 로고    scopus 로고
    • Liver involvement in obese children: Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population
    • Franzese A, Vajro P, Argenziano A, et al. Liver involvement in obese children: ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population. Dig Dis Sci. 1997;42:1428-1432.
    • (1997) Dig Dis Sci , vol.42 , pp. 1428-1432
    • Franzese, A.1    Vajro, P.2    Argenziano, A.3
  • 2
    • 33747077203 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in children: A prospective clinical-pathological study and effect of lifestyle advice
    • Nobili V, Marcellini M, Devito R, et al. Nonalcoholic fatty liver disease in children: a prospective clinical-pathological study and effect of lifestyle advice. Hepatology. 2006;44:458-465.
    • (2006) Hepatology , vol.44 , pp. 458-465
    • Nobili, V.1    Marcellini, M.2    Devito, R.3
  • 3
    • 0036829982 scopus 로고    scopus 로고
    • Noninvasive monitoring of patients with chronic hepatitis C
    • Fontana RJ, Lok AS. Noninvasive monitoring of patients with chronic hepatitis C. Hepatology. 2002;36(5 suppl 1):S57-S64.
    • (2002) Hepatology , vol.36 , Issue.5 SUPPL. 1
    • Fontana, R.J.1    Lok, A.S.2
  • 4
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med. 2000;343:1467-1476.
    • (2000) N Engl J Med , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 5
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology. 1998;114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 6
    • 16644383355 scopus 로고    scopus 로고
    • Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury
    • Ding WX, Yin XM. Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury. J Cell Mol Med. 2004;8:445-454.
    • (2004) J Cell Mol Med , vol.8 , pp. 445-454
    • Ding, W.X.1    Yin, X.M.2
  • 8
    • 20044387026 scopus 로고    scopus 로고
    • IKK-beta links inflammation to obesity-induced insulin resistance
    • Arkan MC, Hevener AL, Greten FR, et al. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med. 2005;11:191-198.
    • (2005) Nat Med , vol.11 , pp. 191-198
    • Arkan, M.C.1    Hevener, A.L.2    Greten, F.R.3
  • 9
    • 0035183475 scopus 로고    scopus 로고
    • Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
    • Crespo J, Cayon A, Fernandez-Gil P, et al. Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology. 2001;34:1158-1163.
    • (2001) Hepatology , vol.34 , pp. 1158-1163
    • Crespo, J.1    Cayon, A.2    Fernandez-Gil, P.3
  • 10
    • 0036031768 scopus 로고    scopus 로고
    • Leptin enhances the effect of transforming growth factor beta in increasing type I collagen formation
    • Tang M, Potter JJ, Mezey E. Leptin enhances the effect of transforming growth factor beta in increasing type I collagen formation. Biochem Biophys Res Commun. 2002;297:906-911.
    • (2002) Biochem Biophys Res Commun , vol.297 , pp. 906-911
    • Tang, M.1    Potter, J.J.2    Mezey, E.3
  • 11
    • 0038644530 scopus 로고    scopus 로고
    • Leptin induces increased alpha2 (I) collagen gene expression in cultured rat hepatic stellate cells
    • Saxena NK, Saliba G, Floyd JJ, et al. Leptin induces increased alpha2 (I) collagen gene expression in cultured rat hepatic stellate cells. J Cell Biochem. 2003;89:311-320.
    • (2003) J Cell Biochem , vol.89 , pp. 311-320
    • Saxena, N.K.1    Saliba, G.2    Floyd, J.J.3
  • 12
    • 27644509152 scopus 로고    scopus 로고
    • Review article: Adipocytokines and insulin resistance
    • Vettor R, Milan G, Rossato M, et al. Review article: adipocytokines and insulin resistance. Aliment Pharmacol Ther. 2005;22(suppl 2):3-10.
    • (2005) Aliment Pharmacol Ther , vol.22 , Issue.SUPPL. 2 , pp. 3-10
    • Vettor, R.1    Milan, G.2    Rossato, M.3
  • 13
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • for the Nonalcoholic Steatohepatitis Clinical Research Network
    • Kleiner DE, Brunt EM, Van Natta M, et al, for the Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313-1321.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 14
    • 0034611996 scopus 로고    scopus 로고
    • Establishing a standard definition for child overweight and obesity worldwide: International survey
    • Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320:1-6.
    • (2000) BMJ , vol.320 , pp. 1-6
    • Cole, T.J.1    Bellizzi, M.C.2    Flegal, K.M.3
  • 15
    • 0032127797 scopus 로고    scopus 로고
    • Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence: A review study
    • Brotons C, Ribera A, Perich RM, et al. Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence: a review study. Atherosclerosis. 1998;139:1-9.
    • (1998) Atherosclerosis , vol.139 , pp. 1-9
    • Brotons, C.1    Ribera, A.2    Perich, R.M.3
  • 16
    • 3442901072 scopus 로고    scopus 로고
    • National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114:555-576
    • National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114:555-576.
  • 17
    • 1842334456 scopus 로고    scopus 로고
    • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 1997;20:1183-1197.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 18
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 19
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • Matsuda M, De Fronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22:1462-1470.
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    De Fronzo, R.A.2
  • 20
    • 0027457620 scopus 로고
    • Receiver-operating characteristic (ROC) plots: A fundamental evaluation tool in clinical medicine
    • Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993;39:561-577.
    • (1993) Clin Chem , vol.39 , pp. 561-577
    • Zweig, M.H.1    Campbell, G.2
  • 21
    • 0023780330 scopus 로고
    • The robustness of the "binormal" assumptions used in fitting ROC curves
    • Hanley J. The robustness of the "binormal" assumptions used in fitting ROC curves. Med Decis Making. 1988;8:197-203.
    • (1988) Med Decis Making , vol.8 , pp. 197-203
    • Hanley, J.1
  • 23
    • 30044431801 scopus 로고    scopus 로고
    • From fat to inflammation
    • Day CP. From fat to inflammation. Gastroenterology. 2006;130:207-210.
    • (2006) Gastroenterology , vol.130 , pp. 207-210
    • Day, C.P.1
  • 24
    • 5344239586 scopus 로고    scopus 로고
    • Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease
    • Videla LA, Rodrigo R, Araya J, et al. Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease. Free Radic Biol Med. 2004;37:1499-1507.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1499-1507
    • Videla, L.A.1    Rodrigo, R.2    Araya, J.3
  • 25
    • 0035125052 scopus 로고    scopus 로고
    • The role of small bacterial overgrowth, intestinal permeability, endotoxinemia, and tumor necrosis alpha in the pathogenesis of nonalcoholic steatohepatitis
    • Wigg AJ, Roberts-Thompson IC, Dymock RB, et al. The role of small bacterial overgrowth, intestinal permeability, endotoxinemia, and tumor necrosis alpha in the pathogenesis of nonalcoholic steatohepatitis. Gut. 2001;48:206-211.
    • (2001) Gut , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thompson, I.C.2    Dymock, R.B.3
  • 26
    • 7044269614 scopus 로고    scopus 로고
    • Beneficial effects of tumor necrosis factor-alpha inhibition by pentoxifylline on clinical, biochemical, and metabolic parameters of patients with nonalcoholic steatohepatitis
    • Satapathy SK, Garg S, Chauhan R, et al. Beneficial effects of tumor necrosis factor-alpha inhibition by pentoxifylline on clinical, biochemical, and metabolic parameters of patients with nonalcoholic steatohepatitis. Am J Gastroenterol. 2004;99:1946-1952.
    • (2004) Am J Gastroenterol , vol.99 , pp. 1946-1952
    • Satapathy, S.K.1    Garg, S.2    Chauhan, R.3
  • 27
    • 0042265627 scopus 로고    scopus 로고
    • Cytokines and NASH: A pilot study of the effects of lifestyle modification and vitamin E
    • Kugelmas M, Hill DB, Vivian B, et al. Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. Hepatology. 2003;38:413-419.
    • (2003) Hepatology , vol.38 , pp. 413-419
    • Kugelmas, M.1    Hill, D.B.2    Vivian, B.3
  • 28
    • 33646161443 scopus 로고    scopus 로고
    • Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
    • Haukeland JW, Damas JK, Konopski Z, et al. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J Hepatol. 2006;44:1167-1174.
    • (2006) J Hepatol , vol.44 , pp. 1167-1174
    • Haukeland, J.W.1    Damas, J.K.2    Konopski, Z.3
  • 29
    • 30944469306 scopus 로고    scopus 로고
    • Adipokines in NASH: Postprandial lipid metabolism as a link between adiponectin and liver disease
    • Musso G, Gambino R, Durazzo M, et al. Adipokines in NASH: postprandial lipid metabolism as a link between adiponectin and liver disease. Hepatology. 2005;42:1175-1183.
    • (2005) Hepatology , vol.42 , pp. 1175-1183
    • Musso, G.1    Gambino, R.2    Durazzo, M.3
  • 30
    • 22144473743 scopus 로고    scopus 로고
    • Metabolic hormonal oxidative, and inflammatory factors in pediatric obesity-related liver disease
    • Mandato C, Lucariello S, Licenziati MR, et al. Metabolic hormonal oxidative, and inflammatory factors in pediatric obesity-related liver disease. J Pediatr. 2005;147:62-66.
    • (2005) J Pediatr , vol.147 , pp. 62-66
    • Mandato, C.1    Lucariello, S.2    Licenziati, M.R.3
  • 31
    • 0037129380 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease
    • Angulo P. Non-alcoholic fatty liver disease. N Engl J Med. 2002;346:1221-1231.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 32
    • 0036022846 scopus 로고    scopus 로고
    • Leptin is essential for the hepatic fibrogenic response to chronic liver injury
    • Leclercq IA, Farrell GC, Schriemer R, et al. Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol. 2003;37:206-213.
    • (2003) J Hepatol , vol.37 , pp. 206-213
    • Leclercq, I.A.1    Farrell, G.C.2    Schriemer, R.3
  • 33
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest. 1998;101:890-898.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3
  • 34
    • 7044241291 scopus 로고    scopus 로고
    • Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: Role of short-form leptin receptors and osteopontin
    • Sahai A, Malladi P, Pan X, et al. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol. 2004;287:G1035-G1043.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Sahai, A.1    Malladi, P.2    Pan, X.3
  • 35
    • 9644265298 scopus 로고    scopus 로고
    • Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease
    • Angulo P, Alba LM, Petrovic LM, et al. Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease. J Hepatol. 2004;41:943-949.
    • (2004) J Hepatol , vol.41 , pp. 943-949
    • Angulo, P.1    Alba, L.M.2    Petrovic, L.M.3
  • 36
    • 33646479192 scopus 로고    scopus 로고
    • Increased production of IL-1 alpha in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease
    • Poniachik J, Csendes A, Diaz JC, et al. Increased production of IL-1 alpha in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease. Cytokine. 2006;33:252-257.
    • (2006) Cytokine , vol.33 , pp. 252-257
    • Poniachik, J.1    Csendes, A.2    Diaz, J.C.3
  • 37
    • 24144444669 scopus 로고    scopus 로고
    • Histopathology of pediatric nonalcoholic fatty liver disease
    • Schwimmer JB, Behling C, Newbury R, et al. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005;42:641-649.
    • (2005) Hepatology , vol.42 , pp. 641-649
    • Schwimmer, J.B.1    Behling, C.2    Newbury, R.3


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